Results 71 to 80 of about 56,978 (263)

Anti-adhesion Property of the Potential Probiotic Strain Lactobacillus fermentum 8711 Against Methicillin-Resistant Staphylococcus aureus (MRSA)

Frontiers in Microbiology, 2018
Methicillin-resistant Staphylococcus aureus (MRSA) is a multidrug-resistant pathogen and one of the leading causes of nosocomial infection worldwide.
Sathyanarayanan Jayashree, Raman Karthikeyan, Sampath Nithyalakshmi, Jothi Ranjani, Paramasamy Gunasekaran, Jeyaprakash Rajendhran   +5 more
doaj   +1 more source

Virtual Twin Approach Using Physiologically Based Pharmacokinetic Modeling to Support Precision Dosing of Valproic Acid in Geriatric Patients

Clinical Pharmacology &Therapeutics, EarlyView.
Personalized dosing is particularly important for drugs with narrow therapeutic indices in geriatric patients, who exhibit substantial physiological variability and limited pharmacokinetic (PK) evidence to guide individualized dose selection. Valproic acid (VPA) is an effective treatment option for bipolar disorder in older adults, yet dosing largely ...
Yoo Jin Jang, Dong‐Gyu Heo, Eunjin Hong   +2 more
wiley   +1 more source

3‐Reactor Chemical Looping System for Point Source CO2 Capture and Subsequent Conversion for Liquid Fuel Production

EcoEnergy, EarlyView.
This study presents a novel 3‐reactor chemical looping system for CO2 capture and subsequent utilization with biomass and natural gas for producing liquid fuels. Using Ca2Fe2O5\Fe2O3 oxygen carriers, it achieves 60% CO2 capture efficiency, ∼80% syngas purity, and autothermal operation, offering a scalable, carbon‐negative route to sustainable fuels ...
Krutarth Pandit, Xiaofeng Jiang, Falguni Akulwar, Danwyn J. Aranha, Rushikesh K. Joshi, Zhuo Cheng, Liang‐Shih Fan   +6 more
wiley   +1 more source

Progress report on new epilepsy treatments: A summary of the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices (EILAT XVIII). II. Treatments in more advanced clinical development

Epilepsia, EarlyView.
Abstract This article summarizes data for 13 investigational treatments for which at least preliminary seizure outcome data in patients with epilepsy were reported at the Eighteenth Eilat Conference on New Antiepileptic Drugs and Devices held in Madrid, Spain, on May 3–6, 2026.
Meir Bialer, Cecilie Johannessen Landmark, Matthias J. Koepp, Emilio Perucca, Piero Perucca, Torbjörn Tomson, H. Steve White, Elaine Wirrell   +7 more
wiley   +1 more source

The gut microbiome and drug‐resistant epilepsy: Microbiome–antiseizure medication interactions and implications for pharmacoresistance

Epilepsia Open, EarlyView.
Abstract Drug‐resistant epilepsy (DRE) affects approximately one‐third of patients with epilepsy and represents a major unmet clinical need. While traditional hypotheses of pharmacoresistance have focused on alterations in drug targets, efflux transporter overexpression, and intrinsic disease severity, the gut microbiome has recently emerged as a ...
Khaled Zammar, Majd A. AbuAlrob, Musab Ali, Simona Lattanzi, Boulenouar Mesraoua   +4 more
wiley   +1 more source

Development of TiO₂–CaCO₃ Based Composites as an Affordable Building Material for the Photocatalytic Abatement of Hazardous NO_x from the Environment

Nanomaterials
This study explores the depollution activity of a photocatalytic cementitious composite comprising various compositions of n-TiO2 and CaCO3. The photocatalytic activity of the CaCO3–TiO2 composite material is assessed for the aqueous photodegradation ...
Madhan Kuppusamy, Sun-Woo Kim, Kwang-Pill Lee, Young Jin Jo, Wha-Jung Kim   +4 more
doaj   +1 more source

The transport mechanism of monocarboxylate transporter on spinosin in Caco-2 cells

Saudi Pharmaceutical Journal, 2016
Objectives: The aim of this study was to determine the uptake mechanism of spinosin (SPI) by the monocarboxylic acid transporters (MCTs) in Caco-2 cells.
Xiang Le Meng, Yan Li Guo, Hai Ying Huang   +2 more
doaj   +1 more source

Potential of Bee Pollen as a Nutraceutical And/Or Functional Ingredient for Metabolic Syndrome Management: In Vitro Antioxidant, Anti‐Inflammatory, and Digestive Enzyme Inhibitory Activities

Food Chemistry International, EarlyView.
Bee pollen samples from China and Spain exhibited in vitro antioxidant, anti‐inflammatory, and digestive enzyme inhibitory activities due to their composition, suggesting their potential as a nutraceutical or functional ingredient to help counteract oxidative stress, chronic inflammation, and metabolic disorders.
Adriana Maite Fernández‐Fernández, Victoria Olt, Jessica Báez, Marcelo Miraballes, Melissa Romero, Cecilia Dauber, Ignacio Vieitez, Estela Santos, Adriana Gámbaro, Alejandra Medrano   +9 more
wiley   +1 more source

Plant‐Derived Extracts Disrupt Biofilm Formation and Quorum Sensing in Yersinia enterocolitica: Insights From GC‐MS and Molecular Docking

Food Chemistry International, EarlyView.
The graphical abstract represents how natural plant products that preferentially target the specific receptors of quorum sensing could be developed to combat biofilms linked to Yersinia enterocolitica using the potent abilities of protein–ligand complexes with high docking scores.
Rajendran Thomas, Songeeta Singha, Devarshi Bharadwaj, Abinash Kumar, Dolly Sharma, Sadhana Ojha, Hirakjyoti Das, Vivek Kumar Gupta   +7 more
wiley   +1 more source

Bacampicillin Uptake Is Shared with Thiamine in Caco-2 Cells

Biological and Pharmaceutical Bulletin, 2007
Bacampicillin was developed as a prodrug to improve the intestinal absorption of its metabolite ampicillin. This study was undertaken to characterize bacampicillin transport in Caco-2 cells. The uptake of bacampicillin in Caco-2 cells was significantly greater than those of ampicillin and pivampicillin.
Oda, Masako, Fujimoto, Kaori, Kobayashi, Michiya, Saitoh, Hiroshi   +3 more
openaire   +3 more sources