Results 71 to 80 of about 97,542,255 (296)

Effects of sinomenine, celecoxib, and sinomenine plus PGE2 on cell proliferation in Caco-2 and MDR-Caco-2 cells.

open access: yes, 2014
Caco-2 and MDR-Caco-2 cells were treated for 48 h with doxorubicin (10−5 to 10 µM) alone or in combination with sinomenine (500 µM), celecoxib (25 µM), or sinomenine (500 µM) plus PGE2 (1 µM). Cell viability was then determined by MTT assay.
Zhi-Jun Duan (573304)   +8 more
core   +1 more source

Carbon metabolism of enterobacterial human pathogens growing in epithelial colorectal adenocarcinoma (Caco-2) cells. [PDF]

open access: yes, 2010
Analysis of the genome sequences of the major human bacterial pathogens has provided a large amount of information concerning their metabolic potential.
Götz Andreas   +12 more
core   +2 more sources

Assembled Hyaluronic Acid Therapeutics for Targeting M1 Macrophages and Regulating Immune Homeostasis for Ulcerative Colitis Treatment

open access: yesAdvanced Science, EarlyView.
An orally administered, drug‐free hyaluronic acid nanoassembly, uhNAs‐OA, accumulates in the inflamed colon and is preferentially internalized by M1‐like macrophages via HA‐CD44 interactions. uhNAs‐OA scavenges excess ROS, suppresses NF‐κB signaling and remodels the colonic immune landscape, resulting in robust therapeutic efficacy in acute, chronic ...
Jianqin Wan   +7 more
wiley   +1 more source

Impact of Glucagon-like Peptide-1 Receptor Agonists on Intestinal Epithelial Cell Barrier

open access: yesEuropean Pharmaceutical Journal
While many types of diabetes medications are currently available, orally administered formulations of glucagon-like peptide-1 (GLP-1) receptor agonists have recently been launched. Therefore, gastrointestinal epithelial cells will be increasingly exposed
Takizawa Y.   +6 more
doaj   +1 more source

Novel method of generation of Ca(HCO3)2 and CaCO3 aerosols and first determination of hygroscopic and cloud condensation nuclei activation properties [PDF]

open access: yesAtmospheric Chemistry and Physics, 2010
Atmospheric mineral aerosols contain CaCO3 as a reactive component. A novel method to produce CaCO3 aerosol was developed by spraying Ca(HCO3)2 solution, which was generated from a CaCO3 suspension and CO2.
A. Trimborn   +10 more
doaj   +1 more source

Transport of Pregabalin in Rat Intestine and Caco-2 Monolayers [PDF]

open access: yesPharmaceutical Research, 1999
The purpose of this study was to determine if the intestinal transport of pregabalin (isobutyl gamma-aminobutyric acid, isobutyl GABA), a new anticonvulsant drug, was mediated by amino acid carriers with affinity for large neutral amino acids (LNAA).Pregabalin transport was studied in rat intestine and Caco-2 monolayers.
Jezyk, Nancy   +5 more
openaire   +3 more sources

Mucus interactions with liposomes encapsulating bioactives: Interfacial tensiometry and cellular uptake on Caco-2 and cocultures of Caco-2/HT29-MTX

open access: yes, 2017
Structuring of delivery matrices in foods aquires careful designing for optimal delivery and subsiquent absorption of the beneficial compounds in the gut.
Guri, Anilda   +4 more
core   +1 more source

Validasi Metode Flooding Dose untuk Mengukur Laju Sintesis Protein pada Sel Caco-2 [PDF]

open access: yes, 2014
Metode flooding dose adalah salah satu teknik yang digunakan untuk mengukur laju sintesis protein.  Metode ini menggunakan asam amino yang diberi label radioaktif bersamaan dengan asam amino yang tidak berlabel radioaktif dalam jumlah yang besar ...
Ulyarti, Ulyarti
core   +1 more source

A Postbiotic‐Inducing Ganoderma applanatum Polysaccharide Repairs the Intestinal Barrier via a Phocaeicola vulgatus ‐ Tridecylic Acid Axis

open access: yesAdvanced Science, EarlyView.
This study identifies GAP2, a bioactive polysaccharide fraction derived from Ganoderma applanatum, as a postbiotic inducer that repairs intestinal barrier damage in a gut microbiota‐dependent manner. GAP2 enriches Phocaeicola vulgatus, which degrades GAP2 and promotes tridecylic acid production, triggering Rho/CDC42 signaling and tight‐junction ...
Chuan Zhang   +10 more
wiley   +1 more source

Caco-2 Cell Culture as a Model for Famotidine Absorption

open access: yesDrug Delivery, 2004
The aim of the study was to determine penetration properties of Famotidine fro the formulations through colon adenocarcinoma (Caco)-2 cell monolayers and to compare in vitro with in vivo test results. It also aimed to determine the effect of particle size on the penetration properties of Famotidine when microsphere formulations were used.
Degim, Z   +3 more
openaire   +3 more sources

Home - About - Disclaimer - Privacy