Results 61 to 70 of about 97,542,255 (296)

Raman spectra of Caco-2 WT and VR

, 2023
Raman spectra and D2O spectra of Caco-2 WT and ...
Jiabao Xu (10530734)
core   +1 more source

Multifunctional Zinc Glycyrrhizinate‐Integrated Gel for Enhanced Probiotic Delivery and Alleviation of Acute and Spontaneous Colitis

Advanced Science, EarlyView.
Multifunctional oral delivery system—L. reuteri@ZGM—act as both a carrier and therapeutic adjuvant, providing ROS scavenging, and mucin‐interactive properties tailored to the IBD microenvironment. This bioactive gel safeguards L. reuteri from gastric degradation, enhances mucosal adhesion, and promotes long‐term retention at inflamed sites, thereby ...
Mengyun Peng, Xiaochun Chen, Wei Li, Shu Tang, Jun Zhou, Xia Wu, Dan Yuan, Zhongyan Shan, Junfeng Shi   +8 more
wiley   +1 more source

Development of New Red-Fleshed Seedless Table Grapes: In Vitro Insights on Glucose Absorption and Insulin Resistance Biomarkers

Foods
There is increasing interest in foods that support both physical and psychological health. Red and black fruits are notable for their high phenolic content and associated biological activities.
Ana Belén Bautista-Ortín, Alejandro Martínez-Moreno, Ana Leticia Pérez-Mendoza, María José Carrasco-Palazón, Lucía Osete-Alcaraz, Laura Soriano-Romaní, Elena Díez-Sánchez, Juan Antonio Nieto, Sonia Soto-Jover, Encarna Gómez-Plaza   +9 more
doaj   +1 more source

Sesquiterpenes α-humulene and β-caryophyllene oxide enhance the efficacy of 5-fluorouracil and oxaliplatin in colon cancer cells

Acta Pharmaceutica, 2019
The present study is designed to find out if sesquiterpenes, α-humulene (HUM), valencene (VAL), β-caryphyllene-oxide (CAO) and trans-nerolidol (NER), are able to improve the antiproliferative effect of classical cytostatic drugs, 5-fluorouracil (FU) and ...
Ambrož Martin, Šmatová Markéta, Šadibolová Michaela, Pospíšilová Eva, Hadravská Pavlína, Kašparová Michaela, Skarková Veronika Hanušová, Králová Věra, Skálová Lenka   +8 more
doaj   +1 more source

Caco-2 Permeability.

, 2015
LDDN-0003499 was assessed for human oral availability and blood brain barrier penetration using a Caco-2 permeability assay.
Marcie A. Glicksman (610360), Gunjan D. Manocha (768264), Kendra L. Puig (334788), Susan A. Austin (768265), Kathleen Seyb (610356), Colin K. Combs (334792)   +5 more
core   +1 more source

Adhesion‐Enhanced Engineered Probiotic for Prolonged Intestinal Retention and Calprotectin‐Responsive IBD Therapy

Advanced Science, EarlyView.
An intelligent engineered probiotic platform is developed for the precision management of inflammatory bowel disease. By integrating surface‐displayed adhesins with an inflammation‐responsive CAT‐SOD‐GPx tripartite fusion system and mucosal repair factors, this programmable system achieves prolonged intestinal retention and multi‐pronged therapy.
Yuxi Wang, Peichao Zhang, Simin Gu, Hongyun Lu, Ningning Jiang, Jiarun Zhao, Enbo Xu, Xiayu Liu, Ying Shi, Qihe Chen   +9 more
wiley   +1 more source

Evaluation of the effect of ethylmethylhydroxypyridine succinate on the activity of the BCRP transporter protein in vitro

Фармакокинетика и Фармакодинамика
Relevance. Breast cancer resistance protein (BCRP) is one of the main clinically significant transporter proteins that play an important role in the pharmacokinetics of drugs.
M. I. Povetko, P. Yu. Mylnikov, A. V. Shchulkin, E. N. Yakusheva   +3 more
doaj   +1 more source

Nanoemulsion for improving solubility and permeability of Vitex agnus-castus extract: formulation and in vitro evaluation using PAMPA and Caco-2 approaches

Drug Delivery, 2017
The purpose of this study was to develop new formulation for an improved oral delivery of Vitex agnus-castus (VAC) extract. After the optimization and validation of analytical method for quali-quantitative characterization of extract, nanoemulsion (NE ...
Vieri Piazzini, Elena Monteforte, Cristina Luceri, Elisabetta Bigagli, Anna Rita Bilia, Maria Camilla Bergonzi   +5 more
doaj   +1 more source

Inhibitory Mechanism of Escherichia coli Adhesion to Caco-2 Monolayers by Polysaccharides from Bangia fusco-purpurea [PDF]

Shipin Kexue
In this study, the effect of Bangia fusco-purpurea polysaccharide (BFP) on Escherichia coli adhesion to Caco-2 monolayers and its potential mechanism was studied using an in vitro human colon adenocarcinoma cell (Caco-2) monolayer model.
DUAN Shushu, ZHENG Mingjing, HONG Tao, ZHU Yanbing, NI Hui, JIANG Zedong
doaj   +1 more source

Apigenin reduces the suppressive effect of exosomes derived from irritable bowel syndrome patients on the autophagy of human colon epithelial cells by promoting ATG14

World Journal of Surgical Oncology, 2023
Background Inflammatory bowel disease (IBS) is a chronic disorder of the gastrointestinal tract. Exosomes have been involved in various pathological processes including IBS. Apigenin has been reported to suppress inflammatory bowel disease (IBS). However,
Rui Fu, Saiyue Liu, Mingjin Zhu, Jiajie Zhu, Mingxian Chen   +4 more
doaj   +1 more source