Results 71 to 80 of about 10,883 (231)

Depression in CADASIL patients [PDF]

Archives of Biological Sciences, 2014
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a hereditary neurological disease accompanied by recurrent ischemic events, characterized by the presence of psychiatric disorders.
Lačković Maja, Damjanović Aleksandar, Ivković Maja, Pantović Maja, Bajčetić Miloš, Rovčanin Branislav, Pavlović Aleksandra, Šternić Nadežda, Jašović-Gašić Miroslava   +8 more
doaj   +1 more source

Impaired vasoreactivity in mildly disabled CADASIL patients [PDF]

, 2011
Background and purpose CADASIL (cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy) is a rare genetic disease caused by NOTCH3 gene mutations.
Campolo, J., De Maria, R., De Stefano, N., Dotti, M.T., Federico, A., Frontali, M., Inzitari, D., Mariotti, C., Pantoni, L., Parodi, O., Pescini, F., Puca, E., Romano, S., Stromillo, M.L., Taroni, F., Tavani, A., Tomasello, C.   +16 more
core   +1 more source

Cognition in CADASIL [PDF]

Stroke, 2009
CADASIL is an early onset small vessel disease and genetic variant of pure subcortical ischemic vascular dementia (SIVD). The condition has been invaluable in defining the profile and neuroimaging correlates of cognitive deficits in pure SIVD. The recent completion of a randomized trial in cognitively impaired CADASIL patients has illustrated the ...
openaire   +2 more sources

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

Brain Pathology, Volume 36, Issue 1, January 2026.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li, Haoying He, Ejuan Zhang, Fengjiao Hu, Zhuo Wang, Jian Xu, Mengliu Zeng, Biwen Peng   +7 more
wiley   +1 more source

Sex differences in frontotemporal atrophy in CADASIL revealed by 7-Tesla MRI

NeuroImage: Clinical, 2023
Brain damage caused by small vessel disease (SVD) differs between males and females. We aimed to examine the pure sex-specific neuroanatomical mechanisms of SVD adjusted for voxel-based expected effects of age and sex on healthy brain volume.
Xiuqin Jia, Chen Ling, Yingying Li, Jinyuan Zhang, Zhixin Li, Xuejia Jia, Danny J.J. Wang, Zihao Zhang, Yun Yuan, Qi Yang   +9 more
doaj   +1 more source

An unusual case of cerebral autosomal-dominant arteriopathy with subcortical infarcts and leukoencephalopathy with occipital lobe involvement

Annals of Indian Academy of Neurology, 2016
Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is an autosomal dominant angiopathy caused by a mutation in the notch 3 gene on chromosome 19.
Bhavesh Trikamji, Mariam Thomas, Gasser Hathout, Shrikant Mishra   +3 more
doaj   +1 more source

Structural MRI [PDF]

, 2011
Predictive genetic testing for a neurogenetic disorder evokes strong emotions, and may lead to distress. The aim of this study is to investigate whether attachment style and emotion regulation strategies are associated with distress in persons who ...
Mike P. Wattjes, Tzourio
core   +5 more sources

Translational models for vascular cognitive impairment: a review including larger species. [PDF]

, 2017
BACKGROUND: Disease models are useful for prospective studies of pathology, identification of molecular and cellular mechanisms, pre-clinical testing of interventions, and validation of clinical biomarkers.
A Bernardo, A Csiszar, A Dal-Pan, A Dreyer, A Fuso, A Joutel, A Joutel, A Kitamura, A Thiel, A Troen, AH Hainsworth, AH Hainsworth, AH Hainsworth, AH Hainsworth, AJ Wells, AM Troen, AM Troen, AM Troen, AM Troen, AP Perez-Sanchez, Aron M. Troen, Atticus H. Hainsworth, B Hallacoglu, B Nitzsche, BJ Cummings, Björn Nitzsche, BS Allen, BT Kang, C Ayata, C Iadecola, C Kilkenny, CA Oomen, Catriona Cunningham, CG Grimberg-Henrici, CH Vite, Chad Farris, CL Gibson, CL Ryan, CM McKittrick, CR Bjarkam, CW Cotman, D Gaffan, D Kaiser, DG McLaren, E Gieling, E Head, E Head, EC Henning, EL Bailey, Elizabeth Head, ET Gieling, ET Gieling, F Dabertrand, F Kuehnel, F Schmidt, FC Rioja-Lang, FE Burrows, FY Jalal, FY Jalal, G Wallays, Gary A. Rosenberg, H Chabriat, H Mahut, HL Gray-Edwards, IM Macrae, J Attems, J Boltze, J Boltze, J Weaver, JA Mattison, JB Madigan, JB Toledo, Jeremy D. Isaacs, JF Arboleda-Velasquez, JF Brittain, JK Chambers, Johannes Boltze, JT O’Brien, JT Skinner, Julie W. Rutten, JW Rutten, K Hattori, K Nishio, K Uchida, K Uchida, K Uchida, K Uchida, L Pantoni, L Rehbein, L Sironi, L Zheng, LC Walker, LS Garosi, M Fisher, M Fisher, M Mietsch, M Monet-Lepretre, M Shibata, Mark B. Moss, Masafumi Ihara, MB Moss, ME Shaul, Melita Salkovic-Petrisic, MJ Schmidt, MM Chakravarty, MM Ruchoux, MP Littman, MR Carmo, MS Conrad, MY Su, NA Terpolilli, ND Prins, NS Jiwa, P McGrath, P Moorhouse, PD Tapp, PD Tapp, PR Holland, R Datta, R Killiany, R Lalonde, Raj N. Kalaria, RN Kalaria, S Brown, S Frey, S Nakamura, S Saikali, S Terlecki, Saskia A. M. J. Lesnik Oberstein, SC Landis, SG Kohama, SH Woolf, SK Liu, Stuart M. Allan, T Freret, T Herrmann, T Ishihara, T Kemper, T Schutt, T Yoshino, TA Baskerville, TL Kemper, TL Moore, TL Sudduth, TL Sudduth, V Bernedo, V Hachinski, V Schmitt, W Hollander, WR Brown, Y Hattori, Y Okamoto, Z Tucsek   +152 more
core   +4 more sources

Virchow-Robin spaces : an anatomic variant or a pathologic sign? [PDF]

, 2009
Virchow-Robin spaces surround blood vessels. Their walls are formed by prolongations of the pia mater and they have no communication with the subarachnoid space. VRS are often seen as well-delineated foci of cerebrospinal fluid signal on MR images.

core  

Vascular neurocognitive disorders and the vascular risk factors [PDF]

, 2018
Dementias are clinical neurodegenerative diseases characterized by permanent and progressive transformation of cognitive functions such as memory, learning capacity, attention, thinking, language, passing judgments, calculation or orientation.
Albu, Carmen V., Albulescu, Dana M., Boldeanu, Mihail V., Bumbea, Ana M., Enescu, Anca S., Enescu, Aurelia, Padureanu, Vlad, Silosi, Cristian A.   +7 more
core   +4 more sources