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Kindler syndrome: A rare case report
Kindler syndrome is a very rare genodermatosis with an autosomal recessive pattern and about 250 cases have been reported worldwide. The mutant gene is Fermitin family homolog 1 gene (KIND1), located on chromosome 20p12.3, which encodes for focal ...
Shweta Satyanarayan Kandikatla+2 more
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Gene regulatory networks and their evolution are important in the study of animal development. In the nematode, Caenorhabditis elegans, the endoderm (gut) is generated from a single embryonic precursor, E.
Morris F. Maduro
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A broad mutational target explains a fast rate of phenotypic evolution
The rapid evolution of a trait in a clade of organisms can be explained by the sustained action of natural selection or by a high mutational variance, that is the propensity to change under spontaneous mutation.
Fabrice Besnard+3 more
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Evolution of susceptibility to ingested double-stranded RNAs in Caenorhabditis nematodes. [PDF]
BACKGROUND: The nematode Caenorhabditis elegans is able to take up external double-stranded RNAs (dsRNAs) and mount an RNA interference response, leading to the inactivation of specific gene expression. The uptake of ingested dsRNAs into intestinal cells
Isabelle Nuez, Marie-Anne Félix
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Background F-box proteins represent a diverse class of adaptor proteins of the ubiquitin-proteasome system (UPS) that play critical roles in the cell cycle, signal transduction, and immune response by removing or modifying cellular regulators.
Ailan Wang, Wei Chen, Shiheng Tao
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Phenotypic covariance of longevity, immunity and stress resistance in the caenorhabditis nematodes. [PDF]
Ageing, immunity and stresstolerance are inherent characteristics of all organisms. In animals, these traits are regulated, at least in part, by forkhead transcription factors in response to upstream signals from the Insulin/Insulin-like growth factor ...
Francis R G Amrit+2 more
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Caenorhabditis nematodes colonize ephemeral resource patches in neotropical forests
Factors shaping the distribution and abundance of species include life‐history traits, population structure, and stochastic colonization–extinction dynamics. Field studies of model species groups help reveal the roles of these factors.
Solomon A. Sloat+14 more
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Surface Acoustic Wave Induced Heat Knockdown of Caenorhabditis Elegans
Model organisms such as Caenorhabditis elegans are commonly used in discovering theunderlying mechanisms of human diseases. The field of microfluidics enables a plethora of tools for better studying these organisms.
Adem Özçelik
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Background The first metazoan genome sequenced, that of Caenorhabditis elegans, has motivated animal genome evolution studies. To date > 50 species from the genus Caenorhabditis have been sequenced, allowing research on genome variation.
Simo Sun+6 more
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Decoding a neural circuit controlling global animal state in C. elegans
Brains organize behavior and physiology to optimize the response to threats or opportunities. We dissect how 21% O2, an indicator of surface exposure, reprograms C.
Patrick Laurent+6 more
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