Results 101 to 110 of about 100,650 (200)
Molecular Nutrition &Food Research, EarlyView.Epicatechin and quercetin enhanced healthspan in the C. elegans BR5270 tauopathy model, associated with the upregulation of autophagy‐related and α‐tubulin synthesis genes, and the downregulation of genes involved in the unfolded protein response. ABSTRACT The prevalence of cognitive disorders such as Alzheimer's disease (AD) is increasing due to the ...
Lidia Garzón‐García +4 more
wiley +1 more source
Targeting gut microbiota as a therapeutic approach for neurodegenerative diseases
Neuroprotection, EarlyView.The abstract depicts the gut‐brain axis, illustrating the bidirectional communication between the gastrointestinal tract and the central nervous system. Probiotics can induce the production of neurotrophins, neurotransmitters, SCFAs, and contribute to increased antioxidant levels, which can benefit brain health. In contrast, antibiotics can disrupt the
Tobiloba S. Olajide +1 more
wiley +1 more source
The role of gut microbiota‐derived metabolites in neuroinflammation
Neuroprotection, EarlyView.Gut microbiota‐derived metabolites accumulate in the brain, activating or inhibiting microglia and astrocytes, which affects neuroinflammatory progression. The gut microbiota converts the diet into a variety of metabolites, including bile acid, trimethylamine N‑oxide (TMAO), and indole.
Lingjie Mu, Yijie Wang
wiley +1 more source
Most \u3cem\u3eCaenorhabditis elegans\u3c/em\u3e MicroRNAs are Individually Not Essential for Development or Viability [PDF]
, 2007 MicroRNAs (miRNAs), a large class of short noncoding RNAs found in many plants and animals, often act to post-transcriptionally inhibit gene expression. We report the generation of deletion mutations in 87 miRNA genes in Caenorhabditis elegans, expanding
Abbott, Allison L. +8 more
core +1 more source
Top‐Down Proteomics: Why and When?
PROTEOMICS, EarlyView.ABSTRACT Manifold biological processes at all levels of transcription and translation can lead to the formation of a high number of different protein species (i.e., proteoforms), which outnumber the sequences encoded in the genome by far. Due to the large number of protein molecules formed in this way, which span an enormous range of different ...
Philipp T. Kaulich, Andreas Tholey
wiley +1 more source
Genetics of Aging in Caenorhabditis elegans
PLoS Genetics, 2007 A dissection of longevity in Caenorhabditis elegans reveals that animal life span is influenced by genes, environment, and stochastic factors. From molecules to physiology, a remarkable degree of evolutionary conservation is seen.
openaire +6 more sources
Interactions of rare earth elements with living organisms and emerging biotechnical applications
PLANTS, PEOPLE, PLANET, EarlyView.Rare earth elements (REEs) are critical resources required to achieve net‐zero carbon emission targets and energy security. However, rising demand for REEs coupled with significant extraction and processing challenges and geopolitical risks restricts access to REE resources.
Samantha A. McGaughey +6 more
wiley +1 more source
The continuing significance of chiral agrochemicals
Pest Management Science, Volume 81, Issue 4, Page 1697-1716, April 2025.In the time frame 2018–2023, around 43% of the 35 chiral agrochemicals introduced to the market (herbicides, fungicides, insecticides, acaricides, and nematicides) contain one or more stereogenic centers in the molecule, and almost 69% of them have been marketed as racemic mixtures of enantiomers or stereoisomers.
Peter Jeschke
wiley +1 more source
Pest Management Science, EarlyView.A new polymeric nanoparticle formulation containing aminophenoxazinone DiS‐NH2 (2,2′‐disulfanediyldianiline) is proposed as a post‐emergence and contact bioherbicide for weed management in durum wheat. Abstract BACKGROUND Weed‐resistance phenomena have increased dramatically in recent years. Bioherbicides can offer a sustainable alternative to chemical
Aurelio Scavo +7 more
wiley +1 more source
The lin-3/let-23 pathway mediates inductive signalling during male spicule development in Caenorhabditis elegans [PDF]
, 1994 During Caenorhabditis elegans male spicule development, four pairs of precursor cells respond to multiple positional cues and establish a pattern of fates that correlates with relative anterior-posterior cell position.
Chamberlin, Helen M., Sternberg, Paul W.
core