Results 171 to 180 of about 148,951 (345)

Multiple forms of histone H2B from the nematode Caenorhabditis elegans [PDF]

, 1986
Jacques R. Vanfleteren, S M Van Bun, L. Delcambe, Jozef J. Van Beeumen   +3 more
openalex   +1 more source

ElixirSeeker: A Machine Learning Framework Utilizing Fusion Molecular Fingerprints for the Discovery of Lifespan‐Extending Compounds

Aging Cell, EarlyView.
ElixirSeeker is a machine learning architecture based on a phenotype‐driven drug discovery approach to screen lifespan‐extending compounds. By integrating molecular fingerprints, ElixirSeeker could maximize feature capture of lifespan‐extending compounds.
Yan Pan, Hongxia Cai, Fang Ye, Wentao Xu, Zhihang Huang, Jingyuan Zhu, Yiwen Gong, Yutong Li, Anastasia Ngozi Ezemaduka, Shan Gao, Shunqi Liu, Guojun Li, Hao Li, Jing Yang, Junyu Ning, Bo Xian   +15 more
wiley   +1 more source

Age-specific nuclear proteins in the nematode worm Caenorhabditis elegans [PDF]

, 1987
Lydie Meheus, Jozef J. Van Beeumen, A. Coomans, Jacques R. Vanfleteren   +3 more
openalex   +1 more source

Rapamycin, Not Metformin, Mirrors Dietary Restriction‐Driven Lifespan Extension in Vertebrates: A Meta‐Analysis

Aging Cell, EarlyView.
The authors provide evidence that, together with Dietary Restriction, Rapamcyin and not Metformin, provides a significant lifespan extension in vertebrates. ABSTRACT Dietary restriction (DR) robustly increases lifespan across taxa. However, in humans, long‐term DR is difficult to maintain, leading to the search for compounds that regulate metabolism ...
Edward R. Ivimey‐Cook, Zahida Sultanova, Alexei A. Maklakov   +2 more
wiley   +1 more source

Data set of differentially expressed microRNAs in sanguinarine-treated Caenorhabditis elegans and its F3 progeny

Data in Brief, 2018
This article presents small RNA sequencing data of Caenorhabditis elegans consist of P0 control worms (untreated), P0 worms treated with a plant alkaloid, sanguinarine, and its F3 offspring.
Yit-Lai Chow, Fumihiko Sato
doaj  

Monoclonal antibodies which distinguish certain classes of neuronal and supporting cells in the nervous tissue of the nematode Caenorhabditis elegans

, 1985
Harumasa Okamoto, J. Nichol Thomson
openalex   +1 more source

MK-801 is a potent nematocidal agent. Characterization of MK-801 binding sites in Caenorhabditis elegans [PDF]

, 1989
James M. Schaeffer, Alan R. Bergstrom, M. J. Turner   +2 more
openalex   +1 more source

The physiological and pathological effects of sphingolipid metabolism and signaling in the central nervous system

Brain Pathology, EarlyView.
Sphingolipids are vital components of cell membranes. Metabolic disruptions of sphingolipids, including ceramide and sphingosine‐1‐phosphate, are linked to neurological disorders. This article summarizes the classification, structure, and metabolic processes of sphingolipids, and the physiological and pathological effects of sphingolipid metabolism and
Tian Li, Haoying He, Ejuan Zhang, Fengjiao Hu, Zhuo Wang, Jian Xu, Mengliu Zeng, Biwen Peng   +7 more
wiley   +1 more source

GENE INTERACTIONS AFFECTING MUSCLE ORGANIZATION IN CAENORHABDITIS ELEGANS [PDF]

, 1985
Susan J. Brown, Donald L Riddle
openalex   +1 more source

A second trans-spliced RNA leader sequence in the nematode Caenorhabditis elegans.

, 1989
Xuming Huang, David Hirsh
openalex   +1 more source