Results 221 to 230 of about 121,076 (308)
Hypoxia results in fragmented mitochondria. Whether this fragmentation promotes or prevents cell death is unresolved. Caenorhabditis elegans mutants defective in mitochondrial fission and fusion coupled with a hypoxia resistant Raptor mutant demonstrated that hypoxia‐induced mitochondrial fragmentation occurs without an intact fission machinery and ...
Julien Goldstick +4 more
wiley +1 more source
Caffeine extends lifespan by enhancing lysosomal lipolysis in Caenorhabditis elegans. [PDF]
Min H +5 more
europepmc +1 more source
This work introduces the concept of pseudoglucosinolates (psGSLs) and reports the synthesis and evaluation of nitroreductase‐responsive psGSLs. These compounds represent a complementary prodrug strategy to natural glucosinolates (GSLs) for the controlled release of isothiocyanates (ITCs), enabling bio‐responsive protein labeling, as demonstrated in ...
Claire C. Jimidar +13 more
wiley +1 more source
Not Just a Fish Killer: Multi-Organ Toxicity and Mechanisms of 6PPD-Quinone. [PDF]
Dong P +7 more
europepmc +1 more source
Caenorhabditis elegans and Drosophila melanogaster as Model Organisms in Biofactor Research
This review presents Caenorhabditis elegans and Drosophila melanogaster as powerful and ethically sound invertebrate model organisms that can be used to investigate nutritional science questions relating to biofactors. Such nutritional phenotyping studies can bridge the gap between in vitro studies and in vivo research in mammals.
Kai Lüersen +2 more
wiley +1 more source
The bacteria of a fig community. [PDF]
Woodruff GC, Moser KA, Wang J.
europepmc +1 more source
The Landscape of BRCA1‐Associated Post‐Translational Modifications
ABSTRACT The BRCA1‐BARD1 complex is a vital protein that promotes homologous recombination, acting through its E3 ubiquitin ligase activity. Although ubiquitination remains its only confirmed enzymatic function, emerging evidence suggests that the complex influences a broad range of post‐translational modifications (PTMs), including methylation ...
Nethma Hewa Waduge +2 more
wiley +1 more source
Keeping neurons in shape with fats: an educational primer for use with "Phospholipid biogenesis maintains neuronal integrity during aging and axon regeneration". [PDF]
Lee RJ, Vaughen JP.
europepmc +1 more source
ABSTRACT Lead is a toxic heavy metal with significant health risks, as maternal lead exposure during pregnancy disrupts fetal neural development through placental transfer, leading to persistent neurological, developmental, and long‐term health consequences in the progeny.
P. Harshitha +3 more
wiley +1 more source

