Results 281 to 290 of about 215,865 (348)

Neuroprotective Potential of the Flavonoids Quercetin and Epicatechin in a C. elegans Tauopathy Model

open access: yesMolecular Nutrition &Food Research, Volume 69, Issue 15, August 2025.
Epicatechin and quercetin enhanced healthspan in the C. elegans BR5270 tauopathy model, associated with the upregulation of autophagy‐related and α‐tubulin synthesis genes, and the downregulation of genes involved in the unfolded protein response. ABSTRACT The prevalence of cognitive disorders such as Alzheimer's disease (AD) is increasing due to the ...
Lidia Garzón‐García   +4 more
wiley   +1 more source

Modeling, virtual screening, and enzymatic docking of trehalose 6‐phosphate phosphatase and evaluation of the insecticidal effect of phthalimide, N‐(p‐tolylsulfonyl) on Aedes aegypti (Diptera: Culicidae)

open access: yesPest Management Science, Volume 81, Issue 8, Page 4777-4787, August 2025.
Schematic diagram of the experimental procedures used to perform the bioinformatic steps and insecticidal assays using trehalose 6‐phosphate phosphatase of Aedes aegypti and the molecule phthalimide, N‐(p‐tolylsulfonyl). Abstract BACKGROUND Aedes aegypti Linnaeus is a medically important vector because of its role in transmitting several arboviruses ...
Raquel Jemima Viana Lima   +3 more
wiley   +1 more source

The ubc-2 gene of Caenorhabditis elegans encodes a ubiquitin-conjugating enzyme involved in selective protein degradation.

open access: green, 1993
Mei Zhen   +4 more
openalex   +1 more source

Revisiting steroidal glycoalkaloids as hatching stimulants for Globodera rostochiensis and Globodera pallida

open access: yesPest Management Science, Volume 81, Issue 8, Page 4848-4862, August 2025.
Structural differences in steroidal glycoalkaloids (SGAs) differentially stimulate hatching in Globodera rostochiensis and Globodera pallida, triggering distinct gene expression responses. These findings offer insights into species‐specific hatching mechanisms, advancing the development of more targeted strategies for managing potato cyst nematode ...
Andrea Caroline Ruthes   +2 more
wiley   +1 more source

Mid-IR Imaging Can Detect Waste Heat Production in the Nematode Caenorhabditis elegans. [PDF]

open access: yesJ Biophotonics
Merritt RA   +4 more
europepmc   +1 more source

Plasmalogen as a Bioactive Lipid Drug: From Preclinical Research Challenges to Opportunities in Nanomedicine

open access: yesFASEB BioAdvances, Volume 7, Issue 8, August 2025.
Plasmalogens are specialized lipids affecting the membrane structure, dynamics, and key cell signaling pathways. They protect cells from oxidative damage. Plasmalogen deficiency is associated with severe diseases. Lipid nanoparticles and nanomedicine offer unexplored therapeutic potential for restoring plasmalogen levels under pathological conditions ...
Yu Wu   +3 more
wiley   +1 more source

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