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Optogenetics in Caenorhabditis elegans
2015With a compact neural circuit consisting of entirely mapped 302 neurons, Caenorhabditis elegans plays an important role in the development and application of optogenetics. Optogenetics in C. elegans offers the opportunity that drastically changes experimental designs with increasing accessibility for neural activity and various cellular processes ...
Yuki, Tsukada, Ikue, Mori
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Transgenesis in Caenorhabditis elegans
2009Two efficient strategies have been developed and are widely used for the genetic transformation of the nematode Caenorhabditis elegans, DNA microinjection, and DNA-coated microparticle bombardment. Both methodologies facilitate the delivery of exogenous DNA into the developing oocytes of adult hermaphrodite animals, which then generate transgenic worms
Matthias, Rieckher +3 more
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Biolistic Transformation of Caenorhabditis elegans
2012The ability to generate transgenic animals to study gene expression and function is a powerful and important part of the Caenorhabditis elegans genetic toolbox. Transgenic animals can be created by introducing exogenous DNA into the worm germline either by microinjection or by microparticle bombardment (biolistic transformation).
Isik, M., Berezikov, E.
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Caenorhabditis elegans Olfaction
2017To survive, animals must properly sense their surrounding environment. The types of sensation that allow for detecting these changes can be categorized as tactile, thermal, aural, or olfactory. Olfaction is one of the most primitive senses, involving the detection of environmental chemical cues. Organisms must sense and discriminate between abiotic and
Douglas K. Reilly, Jagan Srinivasan
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Whole-animal connectomes of both Caenorhabditis elegans sexes
Nature, 2019Steven J Cook +2 more
exaly
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
Nature, 2003Coleen T Murphy +2 more
exaly