Results 21 to 30 of about 193,403 (293)

Caenorhabditis elegans as a Useful Model for Studying Aging Mutations

open access: yesFrontiers in Endocrinology, 2020
The Caenorhabditis elegans genome possesses homologs of about two-thirds of all human disease genes. Based on its physiological aging characteristics and superiority, the use of C.
Siwen Zhang   +4 more
semanticscholar   +1 more source

Identifying the Caenorhabditis elegans vulval transcriptome

open access: yesG3: Genes, Genomes, Genetics, 2022
Development of the Caenorhabditis eleganslag-1C ...
Qi Zhang   +3 more
doaj   +1 more source

Modeling neurodegeneration in Caenorhabditis elegans

open access: yesDisease Models & Mechanisms, 2020
The global burden of neurodegenerative diseases underscores the urgent need for innovative strategies to define new drug targets and disease-modifying factors.
Kim A. Caldwell   +2 more
semanticscholar   +1 more source

Intermediary metabolism [PDF]

open access: yes, 2009
Caenorhabditis elegans has orthologs for most of the key enzymes involved in eukaryotic intermediary metabolism, suggesting that the major metabolic pathways are probably present in this species.
Braeckman, Bart   +2 more
core   +2 more sources

Evolution of susceptibility to ingested double-stranded RNAs in Caenorhabditis nematodes. [PDF]

open access: yesPLoS ONE, 2012
BACKGROUND: The nematode Caenorhabditis elegans is able to take up external double-stranded RNAs (dsRNAs) and mount an RNA interference response, leading to the inactivation of specific gene expression. The uptake of ingested dsRNAs into intestinal cells
Isabelle Nuez, Marie-Anne Félix
doaj   +1 more source

The microbial zoo in the C. elegans intestine: Bacteria, fungi and viruses [PDF]

open access: yes, 2016
Press freedom has become one of the major challenges facing Journalism practice in the world. This paper explores the factors hindering press freedom in Nigeria using some relevant examples.
Jiang, Hongbing, Wang, David
core   +3 more sources

Lifespan extension in Caenorhabditis elegans insulin/IGF-1 signalling mutants is supported by non-vertebrate physiological traits [PDF]

open access: yes, 2017
The insulin/IGF-1 signalling (IIS) pathway connects nutrient levels to metabolism, growth and lifespan in eukaryotes ranging from yeasts to humans, including nematodes such as the genetic model organism Caenorhabditis elegans. The link between ageing and
Braeckman, Bart, Dhondt, Ineke
core   +2 more sources

Evolution of a polymodal sensory response network [PDF]

open access: yes, 2008
Background: Avoidance of noxious stimuli is essential for the survival of an animal in its natural habitat. Some avoidance responses require polymodal sensory neurons, which sense a range of diverse stimuli, whereas other stimuli require a unimodal ...
Durak, Omer   +2 more
core   +4 more sources

Caenorhabditis elegans as a model for obesity research

open access: yesCurrent Research in Food Science, 2021
Caenorhabditis elegans, a free-living nematode, is an animal model that has been extensively employed in a variety of research fields, including in the study of obesity. Its favorable features include its compact size, short life cycle, large brood size,
Yiren Yue   +3 more
doaj  

The worm in the world and the world in the worm

open access: yesBMC Biology, 2012
Caenorhabditis elegans is a preeminent model organism, but the natural ecology of this nematode has been elusive. A four-year survey of French orchards published in BMC Biology reveals thriving populations of C.
Blaxter Mark, Denver Dee R
doaj   +1 more source

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