Proteomics in Caenorhabditis elegans [PDF]
Proteomic approaches are increasingly being used to complement genetic and RNA interference-based studies of gene function in Caenorhabditis elegans. Several strategies to isolate protein complexes from whole worms and individual differentiated cell types have been described.
Arshad Desai, Anjon Audhya
openaire +3 more sources
Evolution of susceptibility to ingested double-stranded RNAs in Caenorhabditis nematodes. [PDF]
BACKGROUND: The nematode Caenorhabditis elegans is able to take up external double-stranded RNAs (dsRNAs) and mount an RNA interference response, leading to the inactivation of specific gene expression. The uptake of ingested dsRNAs into intestinal cells
Isabelle Nuez, Marie-Anne Félix
doaj +1 more source
Evolution of a polymodal sensory response network [PDF]
Background: Avoidance of noxious stimuli is essential for the survival of an animal in its natural habitat. Some avoidance responses require polymodal sensory neurons, which sense a range of diverse stimuli, whereas other stimuli require a unimodal ...
Durak, Omer+2 more
core +4 more sources
Identifying the Caenorhabditis elegans vulval transcriptome
Development of the Caenorhabditis eleganslag-1C ...
Qi Zhang+3 more
doaj +1 more source
LC-MS proteomics analysis of the iInsulin/IGF-1-deficient Caenorhabditis elegans daf-2(e1370) mutant reveals extensive restructuring of intermediary metabolism [PDF]
The insulin/IGF-1 receptor is a major known determinant of dauer formation, stress resistance, longevity, and metabolism in Caenorhabditis elegans. In the past, whole-genome transcript profiling was used extensively to study differential gene expression ...
Braeckman, Bart+7 more
core +2 more sources
Modeling neurodegeneration in Caenorhabditis elegans
The global burden of neurodegenerative diseases underscores the urgent need for innovative strategies to define new drug targets and disease-modifying factors.
Kim A. Caldwell+2 more
semanticscholar +1 more source
CAENORHABDITIS ELEGANS AND ANGIOGENESIS
Abstract: Angiogenesis is sprouting of new capillaries from already existing ones. It is a dynamic process that can be seen in every phase of human life. It is among the dynamic mechanisms of both physiological and pathological processes. Vascular endothelial growth factor is one of the many molecules that play a role in angiogenesis.
KILIÇÇALAN, İbrahim+2 more
openaire +3 more sources
HaematophagicCaenorhabditis elegans [PDF]
AbstractCaenorhabditis elegansis a free-living nematode that resides in soil and typically feeds on bacteria. We postulate that haematophagicC. eleganscould provide a model to evaluate vaccine responses to intestinal proteins from hematophagous nematode parasites, such asNecator americanus.
Veeren M Chauhan, David I Pritchard
openaire +3 more sources
The tailless Ortholog nhr-67 Regulates Patterning of Gene Expression and Morphogenesis in the C. elegans Vulva [PDF]
Regulation of spatio-temporal gene expression in diverse cell and tissue types is a critical aspect of development. Progression through Caenorhabditis elegans vulval development leads to the generation of seven distinct vulval cell types (vulA, vulB1 ...
Fernandes, Jolene S., Sternberg, Paul W.
core +6 more sources
Predicting Phenotypic Diversity and the Underlying Quantitative Molecular Transitions [PDF]
During development, signaling networks control the formation of multicellular patterns. To what extent quantitative fluctuations in these complex networks may affect multicellular phenotype remains unclear.
A Abzhanov+40 more
core +3 more sources