Results 31 to 40 of about 111,262 (297)

In silico Evaluation of mirror repeats within ced-9 Gene of Caenorhabditis elegans

Biomedical and Biotechnology Research Journal, 2023
Background: Repetitive elements constitute a significant proportion of metazoan genomes. These elements form different types of unusual structures, such as left-handed Z-DNA, triple-stranded H-DNA, G-quadruplex, and cruciform, and are related to various ...
Mamta Dhankhar, Deepti Yadav, Vikash Bhardwaj   +2 more
doaj   +1 more source

Proteomics in Caenorhabditis elegans [PDF]

Briefings in Functional Genomics and Proteomics, 2008
Proteomic approaches are increasingly being used to complement genetic and RNA interference-based studies of gene function in Caenorhabditis elegans. Several strategies to isolate protein complexes from whole worms and individual differentiated cell types have been described.
Anjon, Audhya, Arshad, Desai
openaire   +2 more sources

Recent progresses on anti-aging compounds and their targets in Caenorhabditis elegans

Translational Medicine of Aging, 2019
Searching for drugs that extend healthy lifespan and the subsequent analysis of their mechanisms of action is a crucial aspect for aging research. However, identifying both longevity-enhancing drugs and their corresponding targets is challenging.
Eun Ji E. Kim, Seung-Jae V. Lee
doaj   +1 more source

Straightening Caenorhabditis elegans images [PDF]

Bioinformatics, 2007
Abstract Motivation:  Caenorhabditis elegans, a roundworm found in soil, is a widely studied model organism with about 1000 cells in the adult. Producing high-resolution fluorescence images of C.elegans to reveal biological insights is becoming routine, motivating the development of advanced computational tools for analyzing the ...
Peng, Hanchuan, Long, Fuhui, Liu, Xiao, Kim, Stuart K., Myers, Eugene W.   +4 more
openaire   +2 more sources

Biology and genome of a newly discovered sibling species of Caenorhabditis elegans

Nature Communications, 2018
Caenorhabditis nematodes are important model organisms. Here, the authors report the biology and genome of Caenorhabditis inopinata, a first sibling species of C. elegans, and develop genetic and molecular techniques for C. inopinata.
Natsumi Kanzaki, Isheng J. Tsai, Ryusei Tanaka, Vicky L. Hunt, Dang Liu, Kenji Tsuyama, Yasunobu Maeda, Satoshi Namai, Ryohei Kumagai, Alan Tracey, Nancy Holroyd, Stephen R. Doyle, Gavin C. Woodruff, Kazunori Murase, Hiromi Kitazume, Cynthia Chai, Allison Akagi, Oishika Panda, Huei-Mien Ke, Frank C. Schroeder, John Wang, Matthew Berriman, Paul W. Sternberg, Asako Sugimoto, Taisei Kikuchi   +24 more
doaj   +1 more source

The Caenorhabditis elegans DPF‐3 and human DPP4 have tripeptidyl peptidase activity

FEBS Letters, EarlyView.
The dipeptidyl peptidase IV (DPPIV) family comprises serine proteases classically defined by their ability to remove dipeptides from the N‐termini of substrates, a feature that gave the family its name. Here, we report the discovery of a previously unrecognized tripeptidyl peptidase activity in DPPIV family members from two different species.
Aditya Trivedi, Rajani Kanth Gudipati
wiley   +1 more source

Nematophagous fungus Arthrobotrys oligospora mimics olfactory cues of sex and food to lure its nematode prey

eLife, 2017
To study the molecular basis for predator-prey coevolution, we investigated how Caenorhabditis elegans responds to the predatory fungus Arthrobotrys oligospora. C. elegans and other nematodes were attracted to volatile compounds produced by A. oligospora.
Yen-Ping Hsueh, Matthew R Gronquist, Erich M Schwarz, Ravi David Nath, Ching-Han Lee, Shalha Gharib, Frank C Schroeder, Paul W Sternberg   +7 more
doaj   +1 more source

Dielectrophoresis of Caenorhabditis elegans [PDF]

Lab on a Chip, 2011
We demonstrate for the first time the dielectrophoretic trapping and manipulation of a whole animal, the nematode Caenorhabditis elegans. We studied the effect of the electric field on the nematode as a function of field intensity and frequency. We identified a range of electric field intensities and frequencies that trap worms without apparent adverse
Han-Sheng, Chuang, David M, Raizen, Annesia, Lamb, Nooreen, Dabbish, Haim H, Bau   +4 more
openaire   +2 more sources

Molecular bases of circadian magnesium rhythms across eukaryotes

FEBS Letters, EarlyView.
Circadian rhythms in intracellular [Mg2+] exist across eukaryotic kingdoms. Central roles for Mg2+ in metabolism suggest that Mg2+ rhythms could regulate daily cellular energy and metabolism. In this Perspective paper, we propose that ancestral prokaryotic transport proteins could be responsible for mediating Mg2+ rhythms and posit a feedback model ...
Helen K. Feord, Gerben van Ooijen
wiley   +1 more source

Immunometabolism in Caenorhabditis elegans

PLOS Pathogens, 2020
Here, we discuss 5 concepts that have emerged in studies of metabolic and immune interactions in C. elegans. The major emerging theme is that the immune response and the ability to survive pathogen infection is heavily influenced by pathogen-induced changes in host metabolism.
Sarah M. Anderson, Read Pukkila-Worley
openaire   +5 more sources