Results 61 to 70 of about 279,189 (378)

Essential lipid autacoids rewire mitochondrial energy efficiency in metabolic dysfunction‐associated fatty liver disease

open access: yesHepatology, EarlyView., 2022
Increased liver content of DHA‐derived small lipid autacoids (i.e resolvin D1 and maresin 1) associates with enhanced mitochondrial oxidative phosphorylation, fatty acid β‐oxidation and bioenergetic metabolic flux. These features provide hepatic protection from steatotic, pro‐inflammatory and fibrogenic insults.
Cristina López‐Vicario   +12 more
wiley   +1 more source

The compact genome of Caenorhabditis niphades n. sp., isolated from a wood-boring weevil, Niphades variegatus

open access: yesBMC Genomics, 2022
Background The first metazoan genome sequenced, that of Caenorhabditis elegans, has motivated animal genome evolution studies. To date > 50 species from the genus Caenorhabditis have been sequenced, allowing research on genome variation.
Simo Sun   +6 more
doaj   +1 more source

WormCat: An Online Tool for Annotation and Visualization of Caenorhabditis elegans Genome-Scale Data

open access: yesGenetics, 2019
The emergence of large gene expression datasets has revealed the need for improved tools to identify enriched gene categories and visualize enrichment patterns.
A. Holdorf   +6 more
semanticscholar   +1 more source

Robust Genome Editing with Short Single-Stranded and Long, Partially Single-Stranded DNA Donors in Caenorhabditis elegans

open access: yesGenetics, 2018
A robust genome editing pipeline is critical to the vitality of a modern genetic laboratory. Previous studies have shown that Cas9 ribonucleoprotein (RNP)-based editing can be highly effective in Caenorhabditis elegans, particularly...
G. A. Dokshin   +3 more
semanticscholar   +1 more source

The natural history of Caenorhabditis elegans [PDF]

open access: yesCurrent Biology, 2010
SummaryIn the laboratory, the nematode Caenorhabditis elegans lives on the surface of nutrient agar in Petri dishes, feeding on a lawn of the uracil auxotroph strain OP50, an Escherichia coli mutant strain. This sentence sums up the fundamentals of C. elegans ecology, as most of us know it. While over 15,000 articles on diverse biological aspects of C.
Félix, Marie-Anne, Braendle, Christian
openaire   +3 more sources

In silico Evaluation of mirror repeats within ced-9 Gene of Caenorhabditis elegans

open access: yesBiomedical and Biotechnology Research Journal, 2023
Background: Repetitive elements constitute a significant proportion of metazoan genomes. These elements form different types of unusual structures, such as left-handed Z-DNA, triple-stranded H-DNA, G-quadruplex, and cruciform, and are related to various ...
Mamta Dhankhar   +2 more
doaj   +1 more source

Virulence behavior of uropathogenic Escherichia coli strains in the host model Caenorhabditis elegans [PDF]

open access: yes, 2018
Urinary tract infections (UTIs) are among the most common bacterial infections in humans. Although a number of bacteria can cause UTIs, most cases are due to infection by uropathogenic Escherichia coli (UPEC).
Amos   +60 more
core   +1 more source

TOR Signaling in Caenorhabditis elegans Development, Metabolism, and Aging

open access: yesGenetics, 2019
The Target of Rapamycin (TOR or mTOR) is a serine/threonine kinase that regulates growth, development, and behaviors by modulating protein synthesis, autophagy, and multiple other cellular processes in response to changes in nutrients and other cues ...
T. Blackwell   +5 more
semanticscholar   +1 more source

Study on urine biomarkers of radiation-induced injury guided by Caenorhabditis elegans as a model organism

open access: yesRadiation Medicine and Protection, 2021
Objective: Under the guidance of model organism Caenorhabditis elegans with fine olfactory system, small molecular metabolites sensitive to high dose radiation were screened as biomarkers of acute radiation-induced injury, and their metabolic pathways ...
Xin Wu   +4 more
doaj  

Recompleting the Caenorhabditis elegans genome

open access: yesGenome Research, 2019
Caenorhabditis elegans was the first multicellular eukaryotic genome sequenced to apparent completion. Although this assembly employed a standard C. elegans strain (N2), it used sequence data from several laboratories, with DNA propagated in bacteria and
J. Yoshimura   +11 more
semanticscholar   +1 more source

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