Anthelminthic Activity of <i>Piper nigrum</i>, <i>Albizia ferruginea</i>, and <i>Guarea cedrata</i> Against <i>Caenorhabditis elegans</i> and <i>Heligmosomoides polygyrus</i>: In Vitro and In Silico Molecular Docking Approach. [PDF]
Christelle Nadia NA +8 more
europepmc +1 more source
This study employs an integrative in silico approach combining network pharmacology, molecular docking, and molecular dynamics simulations to explore the molecular association between trigonelline and ovarian aging, identifying five hub proteins (MMP9, JAK2, PARP1, HDAC1, and CYP3A4) and three major mechanistic axes related to extracellular matrix ...
Woon Shin Yong +4 more
wiley +1 more source
Characterizing the role of RSD-6 in the biogenesis of virus-derived small interfering RNAs and the modulation of viral pathogenesis. [PDF]
Dahal K, Xia M, Lu J, Yan T, Lu R.
europepmc +1 more source
Ginsenoside Rg1 (Rg1) from Panax ginseng shows multifunctional health effects. Although oral bioavailability is low and blood–brain barrier (BBB) penetration is limited, delivery systems such as liposomes and nanoparticles may improve exposure. Rg1 reduces inflammation/oxidative stress by inhibiting nuclear factor‐κB (NF‐κB) signaling and reactive ...
Hernán Cortés +13 more
wiley +1 more source
ABSTRACT Metallothioneins (MTLs) are small, cysteine‐rich proteins known for their ability to bind metal ions and exhibit flexible, disordered structures. The structural and functional characteristics of metallothionein I (MTL‐1) from Caenorhabditis elegans were investigated, focusing on its behavior in both metal free (MTL‐1 Apo) and metal‐bond states
Nilvea Ramalho de Oliveira +4 more
wiley +1 more source
The Antioxidant and Antiaging Properties of Maillard Reaction Products Derived From Dipeptide Lys-Leu in <i>Caenorhabditis elegans</i>. [PDF]
Jia Y +4 more
europepmc +1 more source
Abstract The associations of polybrominated diphenyl ethers (PBDEs) with biological aging are unclear. This study explores the possible relationship between PBDEs and accelerated aging. Cross‐sectional data from 6,091 subjects of the National Health and Nutrition Examination Survey (NHANES) 2005–2010 and 2015–2016 are analyzed.
Yan Chen +3 more
wiley +1 more source
A Review of the Literature on the Endocrine Disruptor Activity Testing of Bisphenols in <i>Caenorhabditis elegans</i>. [PDF]
Hockicková P +3 more
europepmc +1 more source
ABSTRACT The rapid growth of genome sequencing has outpaced the development of efficient annotation tools, especially for species lacking transcriptome data. To address this challenge, we present QuickProt, a fast, accurate and user‐friendly homology‐based protein annotation tool.
Guisen Chen +8 more
wiley +1 more source
Cross-species evaluation of TANGO2 homologs, including HRG-9 and HRG-10 in <i>Caenorhabditis elegans,</i> challenges a proposed role in heme trafficking. [PDF]
Sandkuhler SE +11 more
europepmc +1 more source

