Results 221 to 230 of about 1,676,429 (284)

The ER–Golgi Lipid Exchanger PsORP1 Is Essential for Phytophthora sojae Development and Is Blocked by Oxathiapiprolin via Its OSBP‐Related Domain (ORD)

Molecular Plant Pathology, Volume 27, Issue 9, September 2026.
PsORP1 anchors ER–Golgi MCSs to mediate PS/PI4P counter‐transport, and oxathiapiprolin targets the ORD to inhibit this lipid exchange. ABSTRACT Oxysterol‐binding protein (OSBP)‐related proteins (ORPs) are indispensable eukaryotic lipid transporters and promising targets for pharmaceutical and agrochemical exploitation.
Xiaofei Liu, Chengcheng Li, Guangda Shao, Qin Peng, Haixia Wang, Jianqiang Miao, Xili Liu   +6 more
wiley   +1 more source

Phosphatase PTP-4 downregulates ATLN-1-mediated host defense against <i>Pseudomonas aeruginosa</i> infection in <i>Caenorhabditis elegans</i>. [PDF]

Front Pharmacol
Xie J, Shi G, Wang M, Zhong Y, Yuan Y, Sun L, Ge B, Xu A.   +7 more
europepmc   +1 more source

The Histone Demethylase JMJD2‐Dependent Regulation of rDNA Transcription and Integrity of Nucleolus Is Required for Fungal Development and Pathogenicity in the Rice Blast Fungus

Molecular Plant Pathology, Volume 27, Issue 9, September 2026.
Alternative splicing of MoJMJD2 generates nucleolar and nuclear isoforms that coordinate development and pathogenicity in Magnaporthe oryzae. In the nucleolus, MoJMJD2T0 promotes rDNA transcription by reducing H3K9me1 at rDNA loci, whereas in the nucleus, MoJMJD2T1 likely maintains nucleolar integrity and indirectly regulates melanin synthesis, cell ...
Song Hee Lee, Taehyeon Kim, Joo Hyun Lee, Jiyeun Park, Ki‐Tae Kim, Hokyoung Son, Junhyun Jeon   +6 more
wiley   +1 more source

ER-to-Golgi transport machinery promotes the excessive cargo-triggered unfolded protein response in C. elegans. [PDF]

PLoS Genet
Guan L, Zhang T, Zhan Z, Wang Y, Huang X, Ding M.   +5 more
europepmc   +1 more source

Systemic and Local Regulation of Root Growth by Vascular Trehalose 6‐Phosphate is Correlated With Re‐allocation of Primary Metabolites Between Shoots and Roots

Plant, Cell &Environment, Volume 49, Issue 9, Page 6361-6379, September 2026.
ABSTRACT Trehalose 6‐phoshpate (Tre6P) is a key signalling molecule that reflects carbon status and integrates it with developmental decision making. Tre6P has been demonstrated to regulate various developmental processes, including vegetative growth, shoot branching, flowering, and root branching.
Moritz Göbel, Jacqueline Foster, Philipp Westhoff, Noemi Skorzinski, Hannah L. Lepper, Maria F. Njo, Markus Schmid, Tom Beeckman, Miloš Tanurdžić, Anna Amtmann, Franziska Fichtner   +10 more
wiley   +1 more source

DDI-4 induces a temperature-sensitive exocytotic remodeling during C. elegans spermiogenesis via nsun-2-dependent sphingosine signaling. [PDF]

PLoS Genet
Shimada Y, Shiraki R, Ogawa C, Kanazawa-Takino N, Karuo Y, Kawai K, Hashimoto M, Yoshida A, Honda A, Adachi J, Kim JD, Fukamizu A, Omote M, Nishimura H.   +13 more
europepmc   +1 more source

A Quarter Century of EHD Protein Research: From Endosomal Recycling to Ciliopathies

Traffic, Volume 27, Issue 3, September 2026.
Human EHD protein subcellular localization. ABSTRACT Eps15 homology domain‐containing proteins comprise a conserved family of membrane‐remodeling ATPases that regulate endocytic trafficking, membrane fission, receptor recycling, primary ciliogenesis and membrane dynamics across eukaryotes. Since the initial identification of EHD1 and its Caenorhabditis
Devin Frisby, Gunjan Misri, Naava Naslavsky, Steve Caplan   +3 more
wiley   +1 more source

An in vivo parallelized reporter assay to uncover tissue-specific splicing regulatory sequences in a multicellular animal. [PDF]

Nucleic Acids Res
Bhatnagar S, Ho J, Sadek NH, Singh I, Zoberman M, Koterniak B, Liu Y, Fusca DD, Cutter AD, Moses AM, Calarco JA.   +10 more
europepmc   +1 more source

Medicinal and Crop Protection Chemistry: Breaking Barriers, Building Synergies

ChemMedChem, Volume 21, Issue 16, 27 August 2026.
A unified view of medicinal and crop protection chemistry reveals shared scientific progress, common challenges, and new opportunities for cross‐disciplinary collaboration. Bridging expertise across both fields could accelerate innovation and actively encourage more sustainable solutions.
Giulia Cazzaniga, Giusy L. Fratello, Alexander T. Apostle, Roberto Orru, David M. Barber, Silvia Gazzola   +5 more
wiley   +1 more source

STARD3 mediates non-vesicular cholesterol transport in Caenorhabditis elegans. [PDF]

J Lipid Res
Battista B, Sambrailo A, Biglione FA, Lombardo VA, Mansilla MC, Albanesi D, Lisa MN, de Mendoza D, Binolfi A.   +8 more
europepmc   +1 more source