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Protein database of Caenorhabditis elegans
Journal of Chromatography B, 2003Whole genome sequencing of the free-living nematode Caenorhabditis elegans is a prominent achievement in genomics and uncovers the existence of enormous known and unknown gene products. Characterization and linking of all gene products are the next challenging theme of biology. Genome-wide researches are already progressing on C. elegans and the fruits
Hiroyuki, Kaji, Toshiaki, Isobe
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Identification of Protein Substrates for Transglutaminase in Caenorhabditis elegans
Biochemical and Biophysical Research Communications, 2001Transglutaminase-dependent cross-linking of proteins leads to protein polymerisation that confers stability as well as resistance to mechanical disruption and chemical attack. Various transglutaminases have been implicated in a wide range of biological phenomena occurring in both extracellular and intracellular compartments, but further clarification ...
A, Mádi +4 more
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Lamin-Binding Proteins in Caenorhabditis elegans
2016The nuclear lamina, composed of lamins and numerous lamin-associated proteins, is required for mechanical stability, mechanosensing, chromatin organization, developmental gene regulation, mRNA transcription, DNA replication, nuclear assembly, and nuclear positioning.
Dobrzynska, Agnieszka +2 more
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Protein Metabolism and Lifespan in Caenorhabditis elegans
2010Lifespan of the versatile model system Caenorhabditis elegans can be extended by a decrease of insulin/IGF-1 signaling, TOR signaling, mitochondrial function, protein synthesis and dietary intake. The exact molecular mechanisms by which these modulations confer increased life expectancy are yet to be determined but increased stress resistance and ...
Geert, Depuydt +2 more
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Claudin Family Proteins in Caenorhabditis elegans
2011In the last decade, the claudin family of integral membrane proteins has been identified as the major protein component of the tight junctions in all vertebrates. The claudin superfamily proteins also function to regulate channel activity, intercellular signaling, and cell morphology.
Jeffrey S, Simske, Jeff, Hardin
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Yolk proteins of Caenorhabditis elegans
Developmental Biology, 1983A group of proteins judged on several criteria to be yolk proteins have been isolated from a homogenate of the nematode Caenorhabditis elegans. Comparison of partial proteolysis fragments indicates that the two bands of a 170,000-dalton doublet (yp170) are closely related; bands observed at 115,000 daltons (yp115) and 88,000 daltons (yp88) appear to be
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Chaperone-Interacting TPR Proteins in Caenorhabditis elegans
Journal of Molecular Biology, 2013The ATP-hydrolyzing molecular chaperones Hsc70/Hsp70 and Hsp90 bind a diverse set of tetratricopeptide repeat (TPR)-containing cofactors via their C-terminal peptide motifs IEEVD and MEEVD. These cochaperones contribute to substrate turnover and confer specific activities to the chaperones.
Veronika, Haslbeck +5 more
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The Heterotrimeric G Protein Genes of Caenorhabditis elegans
2000Caenorhabditis elegans is the first animal, and the first multicellular organism, for which the complete genomic sequence has been determined (The C. elegans Sequencing Consortium 1998). One of the new possibilities in post-sequence genetics is the immediate analysis of complete gene families.
G, Jansen +5 more
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A two-dimensional protein map of Caenorhabditis elegans
ELECTROPHORESIS, 2001A protein map of Caenorhabditis elegans was constructed by using two-dimensional gel electrophoresis followed by peptide mass fingerprinting. A whole worm extract of a mixed population was separated on immobilized pH gradient strips 4-7 L, 3-10 NL, 6-11 L and 12% sodium dodecyl sulfate-polyacrylamide gel eletrophoresis (SDS-PAGE) gels.
S P, Schrimpf +3 more
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Molecular Genetics and Genomics, 2005
Part of the challenge of the post-genomic world is to identify functional elements within the wide array of information generated by genome sequencing. Although cross-species comparisons and investigation of rates of sequence divergence are an efficient approach, the relationship between sequence divergence and functional conservation is not clear ...
Richard, Jovelin, Patrick C, Phillips
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Part of the challenge of the post-genomic world is to identify functional elements within the wide array of information generated by genome sequencing. Although cross-species comparisons and investigation of rates of sequence divergence are an efficient approach, the relationship between sequence divergence and functional conservation is not clear ...
Richard, Jovelin, Patrick C, Phillips
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