Results 251 to 260 of about 132,722 (276)

The Heterotrimeric G Protein Genes of Caenorhabditis elegans

2000
Caenorhabditis elegans is the first animal, and the first multicellular organism, for which the complete genomic sequence has been determined (The C. elegans Sequencing Consortium 1998). One of the new possibilities in post-sequence genetics is the immediate analysis of complete gene families.
G, Jansen, K L, Thijssen, P, Werner, M, van der Horst, E, Hazendonk, R H, Plasterk   +5 more
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A two-dimensional protein map of Caenorhabditis elegans

ELECTROPHORESIS, 2001
A protein map of Caenorhabditis elegans was constructed by using two-dimensional gel electrophoresis followed by peptide mass fingerprinting. A whole worm extract of a mixed population was separated on immobilized pH gradient strips 4-7 L, 3-10 NL, 6-11 L and 12% sodium dodecyl sulfate-polyacrylamide gel eletrophoresis (SDS-PAGE) gels.
S P, Schrimpf, H, Langen, A V, Gomes, C, Wahlestedt   +3 more
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Tat-mediated protein delivery in living Caenorhabditis elegans

Biochemical and Biophysical Research Communications, 2007
The Tat protein from HIV-1 fused with heterologous proteins traverses biological membranes in a transcellular process called: protein transduction. This has already been successfully exploited in various biological models, but never in the nematode worm Caenorhabditis elegans. TAT-eGFP or GST-eGFP proteins were fed to C.
Frédéric, Delom, Delphine, Fessart, Marie-Elaine, Caruso, Eric, Chevet   +3 more
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Tissue-specific synthesis of yolk proteins in Caenorhabditis elegans

Developmental Biology, 1983
The primary site of yolk protein synthesis in the nematode, Caenorhabditis elegans, has been determined. In animals containing no gonadal cells (obtained by laser ablation of the gonadal precursor cells early in development), yolk proteins are present in abundance. This demonstrates that yolk proteins are made outside the gonad.
J, Kimble, W J, Sharrock
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Protein glycosylation lessons from Caenorhabditis elegans

Current Opinion in Structural Biology, 2004
From observations on human diseases and mutant mice, it has become clear that glycosylation plays a major role in metazoan development. Caenorhabditis elegans provides powerful tools to study this problem that are not available in men or mice. The worm has many genes homologous to mammalian genes involved in glycosylation.
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Delaying aging in Caenorhabditis elegans with protein aggregation inhibitors

Biochemical and Biophysical Research Communications, 2017
Recent evidence suggests that during aging there is widespread accumulation of aggregated insoluble proteins, even in the absence of pathological conditions. Pharmacological manipulation of protein aggregation might be helpful to unveil the involvement of protein aggregates during aging, as well as to develop novel strategies to delay aging.
Karina Cuanalo-Contreras, Kyung-Won Park, Abhisek Mukherjee, Lourdes Millán-Pérez Peña, Claudio Soto   +4 more
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Protein oxidation during aging of the nematode Caenorhabditis elegans

Free Radical Biology and Medicine, 2002
The nematode Caenorhabditis elegans has proven a robust genetic model for studies of aging, including the roles of oxidative stress and protein damage. In this review, we focus on the genetics of select long-lived (e.g., age-1, daf-2, daf-16) and short-lived (e.g., mev-1) mutants that have proven useful in revealing the relationships that exist among ...
Naoaki, Ishii, Sataro, Goto, Philip S, Hartman   +2 more
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The location of the major protein in Caenorhabditis elegans sperm and spermatocytes

Developmental Biology, 1982
Abstract Using an affinity-purified antibody to the major sperm protein (MSP) in Caenorhabditis elegans sperm we have shown by immunofluorescence that the MSP is localized in the fibrous bodies of spermatocytes and early spermatids, in the cytoplasm of late spermatids, and in the pseudopods of spermatozoa.
S, Ward, M, Klass
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Patterns of proteins synthesized during development of Caenorhabditis elegans

Developmental Biology, 1979
Abstract Two-dimensional gel electrophoresis has been used to analyze proteins synthesized during postembryonic development of the nematode Caenorhabditis elegans . This organism is favorable for these studies because it has a limited number of cells, it is genetically well-defined, and its development is currently under investigation in several ...
K, Johnson, D, Hirsh
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Cadherin superfamily proteins in Caenorhabditis elegans and Drosophila melanogaster

Journal of Molecular Biology, 2001
The ability to form selective cell-cell adhesions is an essential property of metazoan cells. Members of the cadherin superfamily are important regulators of this process in both vertebrates and invertebrates. With the advent of genome sequencing projects, determination of the full repertoire of cadherins available to an organism is possible and here ...
E, Hill, I D, Broadbent, C, Chothia, J, Pettitt   +3 more
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