Results 181 to 190 of about 6,761 (193)
Crystal structures of human BTG2 and mouse TIS21 involved in suppression of CAF1 deadenylase activity [PDF]
Nucleic Acids Research, 2008 BTG2 is the prototypical member of the TOB family and is known to be involved in cell growth, differentiation and DNA repair. As a transcriptional co-regulator, BTG2 interacts with CCR4-associated factor 1 (CAF1) and POP2 (CALIF), which are key components of the general CCR4/NOT multi-subunit transcription complex, and which are reported to play ...
Xiuna Yang, Masahiro Morita, Hui Wang
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Caf1 regulates Ash1 histone methyltransferase activity via sensing unmodified histone H3
2023AbstractHistone modifications are one of key mechanisms to regulate gene expression. Ash1 is a histone H3K36 methyltransferase and involved in gene activation. Ash1 forms a large complex with Mrg15 and Caf1/p55/Nurf55/RbAp48 (AMC complex). Ash1 subunit alone has very low activity due to the auto-inhibition and the binding of Mrg15 releases the auto ...
Eojin Yoon, Ji-Joon Song
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Novel interaction between CCR4 and CAF1 in rice CCR4–NOT deadenylase complex
Plant Molecular Biology, 2016Rice is an important crop in the world. However, little is known about rice mRNA deadenylation, which is an important regulation step of gene expression at the post-transcriptional level. The CCR4-NOT1 complex contains two key components, CCR4 and CAF1, which are the main cytoplasmic deadenylases in eukaryotic cells.
Wei-Lun, Chou +3 more
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Biochemistry, 2001
A comparative study of the structural and functional properties of recombinant Yersinia pestis Caf1 and human IL-1beta was performed. According to Fourier transform infrared spectroscopy (FTIR) and circular dichroism (CD) data, IL-1beta and Caf1 are typical beta-structural proteins.
Abramov, Vyacheslav +12 more
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A comparative study of the structural and functional properties of recombinant Yersinia pestis Caf1 and human IL-1beta was performed. According to Fourier transform infrared spectroscopy (FTIR) and circular dichroism (CD) data, IL-1beta and Caf1 are typical beta-structural proteins.
Abramov, Vyacheslav +12 more
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Mouse CAF1, a mouse homologue of the yeast POP2 gene, complements the yeast pop2 null mutation
Yeast, 1999The yeast POP2 protein (Pop2p) is a component of a global transcription regulatory complex and is required for gene expression of many genes in Saccharomyces cerevisiae. We constructed POP2 deletion plasmids encoding various Pop2p regions under the native POP2 promoter and found that the minimum functional region was located in two-thirds of the ...
Y, Shimizu-Yoshida +5 more
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[Stabilization energy of the compact Caf1(13-149) subunit from Yersinia pestis].
Biofizika, 2011It has been shown by a variety of methods (circular dichroism, viscosimetry, intrinsic fluorescence, and fluorescence of labels) that, as in the case of small globular proteins the folding-unfolding transition in the Caf1(13-149) subunit under the action of two denaturants (urea and 1,3-dimethylurea) occurs between two major states (unfolded and ...
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Architecture of the Nuclease Module of the Yeast Ccr4-Not Complex: the Not1-Caf1-Ccr4 Interaction
Molecular Cell, 2012Jerome Basquin +2 more
exaly
The cooperative structure of the interleukin-like capsular protein CAF1 of Yersinia pestis
Immunology Letters, 1997A.M. Vasiliev +6 more
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