Results 91 to 100 of about 7,901 (216)
Caspase Inhibitor Diminishes Caffeic Acid-induced Apoptosis in Osteosarcoma Cells [PDF]
, 2017 BACKGROUND: Caffeic acid has been shown to induce apoptosis in MG63 osteosarcoma cells. Along with the apoptotic induction, caffeic acid was shown to activate caspase-8, -9 and -3.
Hudono, K. F. (Karina) +3 more
core +4 more sources
Food Frontiers, Volume 6, Issue 6, Page 2575-2590, November 2025.Metabolic syndrome is characterized by abdominal obesity, hyperglycemia, dyslipidemia, and hypertension. Bioactive compounds extracted from herbs, tea, and coffee using microbial cell factories, particularly resveratrol and caffeic acid, have demonstrated remarkable potential in the management of metabolic syndrome, offering innovative solutions for ...
Tao Li +7 more
wiley +1 more source
ChemistryOpen, Volume 14, Issue 11, November 2025.A library of easily synthesizable CAPE analogs was screened in silico against the dengue virus envelope protein. Compound LQM778 showed stable binding and promising inhibitory potential. This study highlights LQM778 as a candidate for future in vitro validation and structural optimization toward accessible antiviral agents against dengue.
Luis Alfonso Cárdenas‐Granados +9 more
wiley +1 more source
Redox BiologyCaffeic acid phenethyl ester (CAPE) is a hydrophobic phytochemical typically found in propolis that acts as an antioxidant, anti-inflammatory and cardiovascular protector, among several other properties.
Miltha Hidalgo +10 more
doaj +1 more source
Natural Product Communications, 2019 It has been demonstrated that both cucurbitacin I (Cu I) and caffeic acid phenethyl ester (CAPE) have anticancer activities. The current study aimed to examine the proliferation, migration, and colony formation actions of Cu I and CAPE on MCF-7 and MDA ...
Fuat Karakuş +3 more
doaj +1 more source
RelA Inhibits Embryonic Myogenesis by Coordinately Regulating a Novel Distal Enhancer of Myogenin
Advanced Science, Volume 12, Issue 38, October 13, 2025.Maternal obesity (MO) accounts for more than 40% of pregnancies in the United States, induces inflammation, and impairs embryonic myogenesis, known to program muscle dysfunction in offspring. Inflammation enhances the binding of RelA to a novel distal enhancer located 4 kb upstream of myogenin promoter to inhibit embryonic myogenesis, which is ...
Md Nazmul Hossain +9 more
wiley +1 more source
Pharmacology Research & Perspectives, 2019 5‐lipoxygenase (5‐LO) catalyzes the biosynthesis of leukotrienes, potent lipid mediators involved in inflammatory diseases, and both 5‐LO and the leukotrienes are validated therapeutic targets.
Maroua Mbarik +7 more
doaj +1 more source
Division of Natural Products Chemistry [PDF]
, 2004 この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されまし
Banskota A.H. +2 more
core +1 more source
The anticancer properties of dietary polyphenols and its relation with apoptosis [PDF]
, 1955 Aberrantly regulated apoptosis is involved in the pathogenesis of several diseases and defective apoptosis leads to uncontrolled cell proliferation and tumorigenesis.
Fresco, P +3 more
core +2 more sources
Arthritis &Rheumatology, Volume 77, Issue 10, Page 1373-1386, October 2025.Objective JAK inhibition (JAKi) is effective in seronegative spondyloarthropathy (SpA) spectrum disorders, but Tyk2 inhibition failed in SpA spectrum ulcerative colitis, and tofacitinib showed minimal benefit in Crohn disease, which highlights the complex role for JAK/STAT signaling in different inflammatory processes.
Sami Giryes +14 more
wiley +1 more source