Results 71 to 80 of about 7,555 (199)

Caffeic acid phenethyl ester inhibits liver fibrosis in rats

World Journal of Gastroenterology, 2015
To investigate the hepatoprotective effects and antioxidant activity of caffeic acid phenethyl ester (CAPE) in rats with liver fibrosis.A total of 75 male Sprague-Dawley rats were randomly assigned to seven experimental groups: a normal group (n = 10), a vehicle group (n = 10), a model group (n = 15), a vitamin E group (n = 10), and three CAPE groups ...
Mei, Li, Xiu-Fang, Wang, Juan-Juan, Shi, Ya-Ping, Li, Ning, Yang, Song, Zhai, Shuang-Suo, Dang   +6 more
openaire   +2 more sources

Cardiovascular Effects of Caffeic Acid and Its Derivatives: A Comprehensive Review

Frontiers in Physiology, 2020
Caffeic acid (CA) and its phenethyl ester (CAPE) are naturally occurring hydroxycinnamic acids with an interesting array of biological activities; e.g., antioxidant, anti-inflammatory, antimicrobial and cytostatic.
Henrique Silva, Henrique Silva, Nuno Miguel F. Lopes   +2 more
doaj   +1 more source

Two Flavones as Markers for the Distinction of Natural Acacia Honey Based on the UHPLC‐QE‐MS Method and Research on Their Potential Immunomodulatory Activity

Food Science &Nutrition, Volume 14, Issue 6, June 2026.
This study systematically compared the quality characteristics and immunomodulatory activities of natural and commercial honey. A comprehensive strategy combining physicochemical determination, SPE‐UPLC‐Q‐Exactive Orbitrap MS‐based metabolomics, and machine learning‐assisted chemometrics was established to screen differential biomarkers. Hesperetin and
Bingkang Wang, Min Hua, Yuecheng Liu, Meng Li, Ning Zhang, Yi Wu, Qi Gao, Hongfu Sun, Yanpeng Dai, Meng Zhou, Qian Zhou   +10 more
wiley   +1 more source

Microglial Activation Under Hypoxic Conditions in Early Alzheimer's Disease: Can Natural SIRT1 Activators Be Therapeutic Allies in the Inflammation–Energy Axis?

Phytotherapy Research, Volume 40, Issue 6, Page 3354-3368, June 2026.
ABSTRACT Alzheimer's disease (AD) is a progressive neurodegenerative condition characterized by a preclinical stage that typically lasts for decades. Early on during this time, microglia react to pathological changes and become protective and even transiently delay neurodegeneration.
Sara Merlo, Cristiana Lucia Rita Lipari, Aurora Patti, Maria Angela Sortino   +3 more
wiley   +1 more source

In vitro and in vivo neuroprotective effect of caffeic acid phenethyl ester

Journal of Intercultural Ethnopharmacology, 2015
[No abstract available]
Akyol, Sumeyya, Erdemli, Haci Kemal, Armutcu, Ferah, Akyol, Omer   +3 more
openaire   +2 more sources

Antioxidant effect of caffeic acid phenethyl ester in experimentally induced periodontitis

Clinical Oral Investigations, 2021
The aim of the present study was to evaluate the antioxidant effect of systemically administered caffeic acid phenethyl ester (CAPE) in periodontitis.Forty rats were randomly divided into four groups: control, lipopolysaccharide-induced experimental periodontitis (LPS), CAPE 5: LPS+5 μmol/kg/day CAPE, and CAPE 10: LPS+10 μmol/kg/day CAPE.
Feyza Otan Özden, Müge Lütfioğlu, Esra Demir, Birşen Bilgici   +3 more
openaire   +4 more sources

Deep Eutectic Solvents as Sustainable Media for Efficient Recovery of Phenolics From Black (Lycium ruthenicum Murr.) and Red (Lycium barbarum Lam.) Goji Berries: Optimization and Functional Evaluation

Journal of Food Science, Volume 91, Issue 6, June 2026.
ABSTRACT Deep eutectic solvents (DESs) have been frequently preferred over the past decade as alternatives to conventional solvents for the extraction of bioactive compounds from natural products. Meanwhile, black and red goji berries are widely consumed as functional foods due to their many functional properties reported in the literature.
Yusuf Can Gerçek, Naciye Kutlu, Saffet Çelik, Sinan Bayram, Berke Çevik, Fatma Nur Baştürk, Bahar Özmener, Nesrin Ecem Bayram   +7 more
wiley   +1 more source

Water-Mediated Synthesis of (E)-3-(1-Methyl-1H-benzo[d]imidazol-5-yl)-N-phenethylacrylamide, a Caffeic Acid Phenethyl Amide Analogue

Molbank
Caffeic acid phenethyl ester (CAPE) is a phenolic natural product with diverse biological activities, notably anticancer properties. However, its ester group is metabolically unstable.
Muppidi Subbarao, Sean M. Kerwin
doaj   +1 more source

Photophysics of Biological and Biomimetic Sunscreen Molecules

ChemPhotoChem, Volume 10, Issue 5, May 2026.
Recent photochemical and photophysical research into natural and nature‐inspired UV filter molecules is reviewed, with a focus on the application of these systems in next‐generation sunscreens. The results of time‐resolved UV spectroscopy experiments and theoretical studies are discussed.
Michael Hymas, Vasilios G. Stavros
wiley   +1 more source

Propolis and Beeswax in Cosmetics: A Market Survey and Literature Review on Their Relationship and Role in Allergic Contact Dermatitis

Contact Dermatitis, Volume 94, Issue 5, Page 494-503, May 2026.
Propolis is rarely used in conventional cosmetics within the EU, and such products are therefore unlikely to be significant sources of exposure for patients with positive patch test reactions to propolis. There is no evidence that small amounts of propolis in white beeswax (cera alba) in cosmetics can trigger allergic contact dermatitis in individuals ...
Anton C. de Groot, Norbertus A. Ipenburg, Thomas Rustemeyer   +2 more
wiley   +1 more source