Results 61 to 70 of about 3,475 (164)

Fermentation‐Assisted Valorization: A Sustainable Strategy for Turning Fruit By‐Products Into Value‐Added Food Supplements

Food Frontiers, Volume 7, Issue 1, January 2026.
ABSTRACT A substantial proportion of fresh fruit undergoes processing, resulting in underutilized fruit by‑products (FBPs) that are rich in dietary fiber and bioactive compounds. Recent FBP valorization trends demonstrate that fermentation significantly enhances microbiological, nutritional, and sensory attributes, yielding value‑added food supplements.
Abouzar Ghasemi, Salwa Karboune, Denis Groleau, Ismail Fliss   +3 more
wiley   +1 more source

Natural Products Targeting the EGFR/HER2 Axis in Tumorigenesis: Interpretation of Molecular Mechanisms and Recent Insights Into Synergistic Strategies for Cancer Therapy

Food Frontiers, Volume 7, Issue 1, January 2026.
Schematic overview illustrating the anticancer mechanisms of selected natural products (resveratrol, quercetin, berberine) targeting EGFR and HER2 signaling pathways in tumor cells. These compounds inhibit receptor activation and downstream oncogenic cascades, including PI3K/Akt/mTOR, MAPK/ERK, and STAT3 pathways.
Iman Ramli, Anna Maria Posadino, Roberta Giordo, Antonio Barberis, Ylenia Spissu, Redouane Lemoui, William N. Setzer, Javad Sharifi‐Rad, Gianfranco Pintus   +8 more
wiley   +1 more source

Construction and optimization of Caffeic acid phenethyl ester biosynthesis pathway

Xi'an Gongcheng Daxue xuebao
Caffeic acid phenethyl ester (CAPE) has various pharmacological activities; however, its natural sources are limited, and chemical synthesis poses environmental hazards.Its microbial synthesis using synthetic biotechnology will be more in line with green
ZHANG Genlin, LI Yuanyuan, QIU Di, ZHAO JinYu   +3 more
doaj   +1 more source

Probiotic Supplementation With Bifidobacterium longum Subsp. Longum BL21 Improves Glycemic Control and Modulates Gut Microbiota in Type 2 Diabetes: A Randomized Controlled Trial

Food Science &Nutrition, Volume 14, Issue 1, January 2026.
Supplementation with BL21 led to a significant reduction in HbA1c levels (p = 0.026) compared with placebo. Non‐significant trends toward reduction were also observed for FBG and insulin resistance. The intervention was well tolerated, with a safety profile comparable to placebo.
Chengsheng Zhu, Yinhua Liu, Yanyan Chen, Zhiying Wang, Ya Gao, Fei Xu, Junyi Huang   +6 more
wiley   +1 more source

Caffeic Acid Phenethyl Ester (CAPE) in Romanian Propolis

Bulletin of University of Agricultural Sciences and Veterinary Medicine Cluj-Napoca. Animal Science and Biotechnologies, 2014
Introduction. Propolis is an important bee product, rich in biologically active compounds (MAƒrghitaș et al ., 2013). It is collected by the bees  from buds and exudates of different trees and plants and it has been used since ancient times as a natural remedy or in embalming process.
Liviu Alexandru MARGHITAS, Daniel Severus DEZMIREAN, Flavius DRAGLA, Otilia BOBIS   +3 more
openaire   +2 more sources

Beer Production With Umbu (Spondias tuberosa) Using Conventional and Nonconventional Yeast

Journal of Food Science, Volume 91, Issue 1, January 2026.
ABSTRACT This study evaluated the fermentation performance and bioactive properties of beers produced by Pichia kluyveri L131 and commercial Saccharomyces pastorianus, individually and in coculture, in wort enriched with umbu pulp. Fermentation profiles were assessed over 12 days, focusing on yeast population dynamics, carbohydrate consumption, and ...
Diego Pádua de Almeida, Hygor Lendell Silva de Souza, Ana Luiza Dozol, Mariana Moysés Delorme, Vanessa Naciuk Castelo‐Branco, Adriene Ribeiro Lima, Alexandre Soares dos Santos, Nadia Nara Batista, Rosane Freitas Schwan, Gustavo Molina, Cintia Lacerda Ramos   +10 more
wiley   +1 more source

Enhanced H. pylori Treatment Using a β‐Cyclodextrin–Propolis Complex: A Randomized Clinical Trial

BioMed Research International, Volume 2026, Issue 1, 2026.
Background Helicobacter pylori infection poses a significant global health burden, with rising antibiotic resistance and treatment‐related side effects highlighting the need for adjunctive therapies. Propolis, a natural resin with known antimicrobial and anti‐inflammatory properties, suffers from poor solubility and bioavailability.
Aisa Mehri, Shabnam Pourmoslemi, Alireza Khalilian, Mahdi Safari, Erfan Ayubi, Himangshu Himangshu   +5 more
wiley   +1 more source

Impact of Caffeic Acid Phenethyl Ester on Spinal Cord Inflammation in Mice Model of Multiple Sclerosis

Journal of Tropical Life Science
Since the majority of the current therapies lack effectiveness and efficiency in treating Multiple Sclerosis, in addition to their high cost, monitoring during usage, and the serious side effects associated with using this therapy, which in some cases ...
Amin Alnawajha, Agustina Endharti, Sanarto Santoso, Dewi Santosaningsih   +3 more
doaj   +1 more source

From Hive to Health: Anti‐Influenza Properties of Bee Products

International Journal of Microbiology, Volume 2026, Issue 1, 2026.
Bee products have been long adapted as a natural remedy since centuries ago and studied for their bioactive properties including antimicrobial, anti‐inflammatory, antioxidant, and anticancer effects. Viral infections, including influenza, remain a significant global public health complication signifying the urgency for the development of alternative ...
Wei Wei Loo, Hien Tet Lai, Ji Wei Tan, Elena Sorrentino   +3 more
wiley   +1 more source

Caffeic Acid Acts as a Potent Senomorphic and Alleviates Inflammation and Lung Fibrosis by Covalently Targeting Annexin A5 Protein in Mice

Exploration, Volume 5, Issue 6, December 2025.
1. Caffeic acid (CA) is a novel senomorphic. 2. Annexin A5 is the direct protein target of CA in senescent cells. 3. The covalent binding of CA to Annexin A5 protein triggers its degradation, PKCθ deactivation, and the inhibition of the NF‐κB inflammatory pathway. 4. CA effectively alleviates inflammation and lung fibrosis in mouse model.
Yinhua Zhu, Ying Zhang, Qianyu Zhang, Ping Song, Junzhe Zhang, Ang Ma, Chen Wang, Peng Gao, Tong Yang, Lirun Zhou, Qiaoli Shi, Yin Kwan Wong, Yongting Luo, Huan Tang, Jigang Wang   +14 more
wiley   +1 more source