Results 231 to 238 of about 8,207 (238)

Suppression of cell transformation and induction of apoptosis by caffeic acid phenethyl ester

Molecular Carcinogenesis, 2001
AbstractCaffeic acid phenethyl ester (CAPE), which is derived from the propolis of honeybee hives, has been shown to block tumor promotion and to have toxic effects on several cancer cells. The mechanism of the anti–tumor promotion activity of CAPE is unclear, however.
Akira Kaji, Zigang Dong, Masaaki Nomura, Wei-Ya Ma, Ken-ichi Miyamoto   +4 more
openaire   +3 more sources

The effect of caffeic acid phenethyl ester on the prevention of experimentally induced myringosclerosis

International Journal of Pediatric Otorhinolaryngology, 2007
Myringosclerosis is a common sequela of ventilation tube insertion for the treatment of the otitis media with effusion. Several antioxidants have been identified to prevent myringosclerosis. The objective of this study was to investigate the effect of caffeic acid phenethyl ester (CAPE) on the prevention of experimentally induced myringosclerosis ...
Jae Jun Song, Seok Won Park, Seong Keun Kwon, Chang Gun Cho   +3 more
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Effects of Caffeic Acid Phenethyl Ester on Endotoxin-Induced Uveitis in Rats

Current Eye Research, 2005
Caffeic acid phenethyl ester (CAPE) has antimicrobial, anti-inflammatory, antioxidant, immunomodulatory, and carcinostatic properties. In this study, the efficacy of CAPE in endotoxin-induced uveitis (EIU) in rats is investigated.EIU was induced by a footpad injection of lipopolysaccharide (LPS). In the treatment group, 10 micromol/kg CAPE was injected
Ayça Yilmaz, Özay Öz, Halil Vatansever, Özlem Yildirim, Leyla Cinel, Ugur Atik, Lülüfer Tamer, Arzu Kanik, Ulas Degirmenci   +8 more
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Antioxidant activity of propolis: role of caffeic acid phenethyl ester and galangin

Fitoterapia, 2002
Propolis, a natural product produced by the honeybee, has been used for thousands of years in folk medicine for several purposes. The extract contains amino acids, phenolic acids, phenolic acid esters, flavonoids, cinnamic acid, terpenes and caffeic acid.
RUSSO, Alessandra, R. LONGO, A. VANELLA
openaire   +4 more sources

Radio-Modulatory Potential of Caffeic Acid Phenethyl Ester: A Therapeutic Perspective

Anti-Cancer Agents in Medicinal Chemistry, 2018
Background: Use of natural agents is an upcoming area of research in cancer biology. Caffeic acid phenethyl ester (CAPE) has received great attention because of its therapeutic potential in various conditions including cancer. It is an active/abundant component of propolis, a honey bee hive product produced by bees using their enzyme-rich digestive ...
Km Anjaly, Ashu Bhan Tiku
openaire   +3 more sources

Caffeic Acid Phenethyl Ester Ameliorated Ototoxicity Induced by Cisplatin in Rats

Journal of Chemotherapy, 2004
Caffeic acid phenethyl ester (CAPE), an active component of propolis, exhibits antioxidant properties. This experimental study was designed to determine the effect of CAPE on ototoxicity induced with cisplatin. Twenty-four adult Wistar albino rats were divided into four groups: cisplatin (n=6), saline (n=6), CAPE (n=6), and cisplatin plus CAPE (n=6 ...
Orhan Ozturan, Elif Ozerol, Mukaddes Gulec, Mahmut Tayyar Kalcioglu, Ahmet Kizilay, Omer Akyol, Meryem Iraz   +6 more
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Enzymatic synthesis of caffeic acid phenethyl ester analogues in ionic liquid

Journal of Biotechnology, 2010
An efficient procedure for transesterification of methyl caffeate was developed to produce caffeic acid phenethyl ester analogues with Candida antarctica lipase B using an ionic liquid, 1-butyl-3-methylimidazolium bis(trifluoromethylsulfonyl)imide, as a solvent.
Tokio Fujita, Yoshitaka Hirota, Atsushi Kurata, Mina Furusawa, Kazuya Iwai, Shiori Irie, Yuki Kitamura, Shintaro Takemoto, Yoshiaki Akai, Noriaki Kishimoto   +9 more
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Antitumor effect of propolis : a comparison with caffeic acid and caffeic acid phenethyl ester

1999
The antitumor effect of a water soluble derivative of propolis (WSDP) caffeic acid (CA) and caffeic acid phenethyl ester (CAPE), components of natural propolis, were investigated. The oral administration of these compounds (50 mg/kg or 150 mg/kg) given before or after tumor cell inoculation supressed tumor growth of a weakly immunogeneic mammary ...
Brbot-Šaranović, Ana, Horvat Knežević, Anica, Kocijan, Ivna, Oršolić, Nada, Bendelja, Krešo, Rabatić, Sabina, Bašić, Ivan   +6 more
openaire   +1 more source