Results 241 to 250 of about 12,490 (282)

Microencapsulation of caffeic acid phenethyl ester and caffeic acid phenethyl amide by inclusion in hydroxypropyl-β-cyclodextrin

Food Chemistry, 2018
Caffeic acid phenethyl ester (CAPE) is a bioactive polyphenolic compound obtained from propolis extract. Although it has a broad therapeutic potential, the bioavailability of CAPE is limited, due to reduced solubility and poor plasmatic stability. Efforts to reduce these pharmacokinetic drawbacks resulted in the synthesis of caffeic acid phenethyl ...
E. Manuela P.J. Garrido, Ana S. Cerqueira, Daniel Chavarria, Tiago Silva, Fernanda Borges, Jorge M.P.J. Garrido   +5 more
openaire   +2 more sources

Effects of Caffeic Acid Phenethyl Ester on Pancreatitis in Rats

Journal of Surgical Research, 2008
This study investigated the effect of caffeic acid phenethyl ester (CAPE) on acute necrotizing pancreatitis (ANP) induced by glycodeoxycholic acid in rats. CAPE, an active component of honeybee propolis, has previously been determined to have antioxidant, anti-inflammatory, antiviral, and anticancer activities.Forty-eight rats were divided into four ...
ERDOĞAN, SELİM, TOPALOĞLU, SERDAR, Ercin, Cengiz, KAKLIKKAYA, NEŞE, Alhan, Etem, ATEŞ, BURHAN, Vanizor, Birgul Kural, TÜRKYILMAZ, SERDAR   +7 more
openaire   +3 more sources

Caffeic acid phenethyl ester induces radiosensitization via inhibition of DNA damage repair in androgen‐independent prostate cancer cells

Environmental Toxicology, 2022
In the present study, we evaluated the radiomodulatory potential of caffeic acid phenethyl ester (CAPE), an active component of traditional herbal medicine propolis.
Km Anjaly, A. B. Tiku
semanticscholar   +1 more source

Caffeic Acid Phenethyl Ester (CAPE)

Shock, 2014
Excessive free radical production by immune cells has been linked to cell death and tissue injury during sepsis. Peroxynitrite is a short-lived oxidant and a potent inducer of cell death that has been identified in several pathological conditions. Caffeic acid phenethyl ester (CAPE) is an active component of honeybee products and exhibits antioxidant ...
Mustafa, Kassim, Marzida, Mansor, Tengku Ain, Kamalden, Ina Ismiarti, Shariffuddin, Mohd Shahnaz, Hasan, Gracie, Ong, Shamala Devi, Sekaran, Anwar, Suhaimi, Nazeh, Al-Abd, Kamaruddin Mohd, Yusoff   +9 more
openaire   +2 more sources

Co-delivery of quercetin and caffeic-acid phenethyl ester by polymeric nanoparticles for improved antitumor efficacy in colon cancer cells

Journal of Microencapsulation, 2021
Aim This study aimed to synthesise quercetin- caffeic-acid phenethyl ester (CAPE)-co-loaded poly(lactic-co-glycolic-acid) (PLGA) nanoparticles (QuCaNP) and investigate their anti-cancer activity on human colorectal carcinoma HT-29 cells.
Reyhan Dilsu Colpan, A. Erdemir
semanticscholar   +1 more source

Caffeic acid and its derivative caffeic acid phenethyl ester as potential therapeutic compounds for cardiovascular diseases: A systematic review

Archiv der Pharmazie
Cardiovascular diseases (CVDs) contribute to major public health issues. Some studies have found that caffeic acid (CA) and caffeic acid phenethyl ester (CAPE) may effectively prevent or treat CVDs.
Arya Nasimi Shad, Iman Akhlaghipour, Atefeh Babazadeh Baghan, V. Askari, Vafa Baradaran Rahimi   +4 more
semanticscholar   +1 more source

The effect of caffeic acid phenethyl ester (CAPE) on tympanosclerosis

International Journal of Pediatric Otorhinolaryngology, 2017
To investigate the effects of caffeic acid phenethyl ester (CAPE) on tympanosclerosis.Thirty-two male Sprague Dawley rats were separated into 4 groups as CAPE (n = 10), alcohol (n = 10), control (n = 8) and normal (n = 4) groups. All tympanic membranes except normal group were myringotomised and type 3 Streptococcus pneumoniae strains was injected into
İbrahim, Ağrı, Arzu, Erdal Ağrı, Mehmet Eser, Sancaktar, Asude, Ünal, Erkan, Can, Mustafa, Bakırtaş, Fatih, Yılmaz, Mehmet Derya, Demirağ, Recep, Ünal   +8 more
openaire   +2 more sources

Caffeic acid phenethyl ester ameliorates cadmium-induced kidney mitochondrial injury

Chemico-Biological Interactions, 2012
This study examined whether caffeic acid phenethyl ester (CAPE) can protect kidney mitochondria against cadmium toxicity. Kidney mitochondria isolated from Wistar rat were exposed to cadmium and/or CAPE at various concentrations. Mitochondrial function, ultrastructure and oxidative stress status were determined.
Anongporn, Kobroob, Nipon, Chattipakorn, Orawan, Wongmekiat   +2 more
openaire   +2 more sources

Caffeic acid phenethyl ester ameliorates colistin‐induced nephrotoxicity in rats via modulation of FOXO1/Nrf2/Sirt1 axis

Clinical and Experimental Pharmacology and Physiology
Colistin (Cst) is one of the antimicrobial peptides and is reserved for use against multi‐drug‐resistant Gram‐negative bacteria. However, the clinical value of Cst is limited by its nephrotoxic adverse effects.
M. Nasrullah, Thikryat Neamtalllah, Mohannad Alshibani, Alaa A Bagalagel, A. Noor, Hussain T Bakhsh, Ashraf B. Abdel-Naim   +6 more
semanticscholar   +1 more source

Therapeutic Potential of Caffeic Acid Phenethyl Ester (CAPE) in Diabetes

Current Medicinal Chemistry, 2019
Diabetes mellitus is a complex metabolic disease characterized by high blood sugar levels. Different pathogenic processes are involved in the etiology of the disease. Indeed, chronic diabetes hyperglycemia is often associated with severe long-term complications including cardiovascular symptoms, retinopathy, nephropathy, and neuropathy.
PITTALA', Valeria, SALERNO, Loredana, ROMEO, Giuseppe, ACQUAVIVA R, DI GIACOMO, Claudia, SORRENTI, Valeria   +5 more
openaire   +2 more sources