Results 91 to 100 of about 265,014 (287)

Immunocytochemical localization of chromatin regions UV-microirradiated in S phase or anaphase : Evidence for a territorial organization of chromosomes during cell cycle of cultured Chinese hamster cells [PDF]

, 1983
Chinese hamster cells (M3-1 line) in S phase were laser-UV-microirradiated (λ, 257 nm) at a small site of the nucleus. Cells were fixed either immediately thereafter or in subsequent stages of the cell cycle, including prophase and metaphase.
Avivi, Bennett, Berns, Boveri, Boveri, Comings, Cornelis, Cornelis, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Cremer, Earnshaw, Gray, Hager, Hancock, Hancock, Hens, Laemmli, Rabl, Regan, Sakharov, Sedat, Sperling, Stack, Trosko, Vogel, Zorn   +33 more
core   +1 more source

Cannabinoids and drug–drug pharmacokinetic interactions: Deciphering the risks

British Journal of Clinical Pharmacology, EarlyView.
The relationship between cannabinoids and mental health has become a major focus of scientific inquiry and public discourse. Cannabinoids are diverse chemical compounds from the Cannabis species that have been explored for their therapeutic applications in treating chronic pain, psychiatric and neurological conditions, such as depression, schizophrenia,
Paraskevi Papakyriakopoulou, Georgia Valsami, Georgios Ismailos   +2 more
wiley   +1 more source

cAMP-Inhibits Cytoplasmic Phospholipase A(2) and Protects Neurons against Amyloid-beta-Induced Synapse Damage [PDF]

, 2015
A key event in Alzheimer’s disease (AD) is the production of amyloid-β (Aβ) peptides and the loss of synapses. In cultured neurons Aβ triggered synapse damage as measured by the loss of synaptic proteins. α-synuclein (αSN), aggregates of which accumulate
Bate, C, Williams, A
core   +2 more sources

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +3 more
wiley   +1 more source

Caffeine intake and awareness of its adverse effects: Insights from the medical students at the University of Tabuk.

PLoS ONE
Background/objectivesMedical students may consume more caffeine-containing beverages to cope with their stressors, resulting in negative effects on physical or mental well-being.
Omnia S El Seifi, Faten Ezzelarab Younis, Nouf Ali Alsaiari, Rama Mathel Alanazi, Atheer Khalaf Alanazi, Lama Mana Alamri, Mona Salem Albalawi, Shahad Hammad Alatawi, Eman M Mortada   +8 more
doaj   +1 more source

Growth Pattern and Degradation Activity of Caffeine-degrading Bacteria Consortium

Jurnal Ilmu Dasar
Caffeine-degrading bacteria can be used as agents to degrade caffeine, thereby reducing the concentration of caffeine in organic waste. The decomposition process is carried out by a single bacterium or a consortium of bacteria.
Nadhea Ayu Suksma, Esti Utarti, Sattya Arimurti   +2 more
doaj   +1 more source

Caffeine Consumption and Mortality in Diabetes: An Analysis of NHANES 1999–2010

Frontiers in Endocrinology, 2018
Aim: An inverse relationship between coffee consumption and mortality has been reported in the general population. However, the effect of coffee consumption in diabetes remains unclear.
João Sérgio Neves, João Sérgio Neves, Lia Leitão, Rita Magriço, Miguel Bigotte Vieira, Catarina Viegas Dias, Ana Oliveira, Davide Carvalho, Davide Carvalho, Brian Claggett   +9 more
doaj   +1 more source

The effect of caffeine mouth rinse on self-paced cycling performance [PDF]

, 2014
The aim of the study was to determine whether caffeine mouth rinse would improve 30 min self-paced cycling trial. Twelve healthy active males (age 20.5±0.7 years, mass 87.4±18.3 kg) volunteered for the study.
Barry, G., Bolton, J, Bottoms, Lindsay, Hurst, Howard Thomas, Lynch, F, Scriven, A, Shone, Z., Sinclair, Jonathan Kenneth, Vercoe, L.   +8 more
core   +1 more source

Toward personalized healthcare: Advances in two‐dimensional nanomaterial‐based flexible electrochemical sensors for physiological monitoring

BMEMat, EarlyView.
This review provides an overview of the properties, composites and application of two‐dimensional (2D) nanomaterials for wearable electrochemical biosensors. Also, the challenges and future prospects of utilizing 2D nanomaterials in wearable electrochemical biosensor applications are discussed.
Kou Zhang, Lu Han, He‐Qing Cai, Xin‐Yu Xue, Yi‐Fei Song, Wu‐Lin Xin, Ying‐Ze Wang, Peng Liu, Juan Liu   +8 more
wiley   +1 more source

Design, formulation and evaluation of caffeine chewing gum

Advanced Biomedical Research, 2013
Background: Caffeine which exists in drinks such as coffee as well as in drug dosage forms in the global market is among the materials that increase alertness and decrease fatigue.
Abolfazl Aslani, Fatemeh Jalilian
doaj   +1 more source