Results 71 to 80 of about 143,456 (314)

Comparative Study of Two Turkish Coffee Brands Sold in Saudi Market [PDF]

ERU Research Journal
Objective: Globally, coffee is considered one of the most widely consumed morning beverages due to its intense taste and stimulating effects, which are mostly ascribed to its caffeine concentration.
Sherouk Hussein Sweilam, Maymonah Alotaibi, Rawan Alanazi, Ahmed Foudah   +3 more
doaj   +1 more source

Clinical Function Assignment of NAT2 Alleles by the Clinical Pharmacogenetics Implementation Consortium Pharmacogene Curation Expert Panel

Clinical Pharmacology &Therapeutics, EarlyView.
NAT2 encodes arylamine N‐acetyltransferase 2, a key enzyme in the phase II metabolism of arylamines and arylhydrazines. NAT2 is highly polymorphic, resulting in variable distributions of rapid and poor metabolizers across global populations. Here, we detail the process undertaken by the Clinical Pharmacogenetics Implementation Consortium (CPIC) NAT2 ...
Bailey M. Tibben, David W. Hein, Michelle Whirl‐Carrillo, Andrea Gaedigk, Michael T. Eadon, Rodney F. Minchin, Sotiria Boukouvala, Adalberto Rezende Santos, Roseann S. Donnelly, José A. G. Agúndez, Kelly E. Caudle   +10 more
wiley   +1 more source

Caffeine intake and awareness of its adverse effects: Insights from the medical students at the University of Tabuk.

PLoS ONE
Background/objectivesMedical students may consume more caffeine-containing beverages to cope with their stressors, resulting in negative effects on physical or mental well-being.
Omnia S El Seifi, Faten Ezzelarab Younis, Nouf Ali Alsaiari, Rama Mathel Alanazi, Atheer Khalaf Alanazi, Lama Mana Alamri, Mona Salem Albalawi, Shahad Hammad Alatawi, Eman M Mortada   +8 more
doaj   +1 more source

Principal Components Analysis of Spot Urine Caffeine and Caffeine Metabolites Identifies Promising Exposure Biomarkers of Caffeine and Theobromine Intake in a Cross-Sectional Survey of the United States Population (National Health and Nutrition Examination Survey 2009–2014)

Current Developments in Nutrition
Background: Spot urine concentrations of caffeine and certain caffeine metabolites correlate well with 24-h caffeine intake and have potential use as caffeine exposure biomarkers.
Ching-I Pao, Michael E Rybak, Maya R Sternberg   +2 more
doaj   +1 more source

Non‐Invasive Estimation of Systemic Drug Exposure Using Exhaled Breath Metabolomics in Humans: A Translational Proof‐of‐Concept Study

Clinical Pharmacology &Therapeutics, EarlyView.
Accurate assessment of systemic drug exposure in humans remains challenging, as conventional approaches rely on intermittent blood sampling and laboratory‐based assays that are invasive and provide limited temporal resolution. Exhaled breath contains volatile and semi‐volatile compounds arising from drug metabolism and downstream biological processes ...
Kai Fricke, Diego M. Baur, Kapil Dev Singh, Felix Schmidt, Kathrin Müsch, Noriane A. Sievi, Marco Di Donato, Anton Schmick, Jonas Herth, Silvia Ulrich, Pablo Sinues, Marian Galovic, Malcolm Kohler   +12 more
wiley   +1 more source

Cortical Thickness and Appetite Hormones in Adolescent Obesity and Binge Eating Disorder: A Comparative Study

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective This study examined cortical thickness and appetite‐regulating hormones—neuropeptide Y (NPY) and ghrelin—to better understand the neurobiological mechanisms underlying binge eating disorder (BED) and obesity in adolescence. We compared adolescents with BED and obesity, adolescents with obesity without BED, and healthy controls (HCs),
Serkan Turan, İbrahim Mert Erbaş, Fatma Ceren Sarıoğlu, Berrin Çavuşoğlu, Ezgi Molla, Ali Rıza Şişman, Sevay Alsen Güney, Handan Güleryüz, Ayhan Abacı, Yeşim Öztürk, Aynur Pekcanlar Akay   +10 more
wiley   +1 more source

Short- and long-term neurobehavioural impairments in mice offspring following chronic perinatal caffeine exposure and withdrawal

BMC Neuroscience
This study explored neurodevelopmental and adult neurobehavioural outcomes in mouse offspring following chronic perinatal caffeine exposure and subsequent withdrawal.
Funmilayo Eniola Olopade, Oluwabusayo Racheal Folarin, Taidinda Tashara Gilbert, James Olukayode Olopade   +3 more
doaj   +1 more source

Psilocybin as a Transdiagnostic Treatment for Eating Disorders and Comorbid Psychopathology: Implications for Clinical Nosology and Research Directions

International Journal of Eating Disorders, EarlyView.
ABSTRACT Objective Eating disorders (EDs) are characterized by high rates of psychiatric comorbidity and suboptimal treatment outcomes. There remain critical gaps in research, including the exploration of effective transdiagnostic interventions. This forum article examines the potential of psilocybin treatment (PT) as a transdiagnostic intervention for
Elena Koning, Jérémie Richard, Aaron Keshen   +2 more
wiley   +1 more source

Caffeine intake by patients with autosomal dominant polycystic kidney disease

Brazilian Journal of Medical and Biological Research, 2012
Because caffeine may induce cyst and kidney enlargement in autosomal dominant polycystic kidney disease (ADPKD), we evaluated caffeine intake and renal volume using renal ultrasound in ADPKD patients.
L.C. Vendramini, J.L. Nishiura, A.C. Baxmann, I.P. Heilberg   +3 more
doaj   +2 more sources

Effects of Caffeine on Cardiovascular Toxicity in Adult Wistar Rats

Journal of Applied Sciences and Environmental Management
Caffeine has been used for thousands of years. When taken in excess, caffeine can have negative effects on the body's overall health, including the cardiovascular system.
B. P. Onyeije, S. O. Innih
doaj