Results 51 to 60 of about 143,456 (314)
BMC Cancer, 2019 Background While multiagent chemotherapy has dramatically improved the prognosis of sarcoma, the novel chemotherapeutics have hardly developed over the past 30 years.
Kensaku Abe +4 more
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Application of the Caffeine in Antiviral Medications through Polynomials and Topological Descriptors [PDF]
, 2023 Zeeshan Afzal, Faisal Yasin
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Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)
British Journal of Clinical Pharmacology, EarlyView.Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul +7 more
wiley +1 more source
British Journal of Clinical Pharmacology, EarlyView.Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden +3 more
wiley +1 more source
Effects of caffeine on sleep quality and daytime functioning
Risk Management and Healthcare Policy, 2018 Frances O’Callaghan,1 Olav Muurlink,2,3 Natasha Reid4 1School of Applied Psychology, Griffith Health, Griffith University, Southport, QLD, Australia; 2School of Business and Law, Central Queensland University, Brisbane, QLD, Australia; 3Griffith ...
O'Callaghan F, Muurlink O, Reid N
doaj
Effect Of Caffeine On Exercise Performance: Current Review
Türk Spor ve Egzersiz Dergisi, 2021 Caffeine is an ergogenic supplement that has been attracting attention in the sports community for many years. It has been proven in many studies that coffee consumption has a positive effect on exercise performance.
Yusuf Buzdağlı +3 more
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Development of a nalmefene formulation suitable for a community‐use auto‐injector
British Journal of Clinical Pharmacology, EarlyView.Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano +6 more
wiley +1 more source
Scientific Opinion on the safety of caffeine
EFSA Journal, 2015 Following a request from the European Commission, the EFSA Panel on Dietetic Products, Nutrition and Allergies was asked to deliver a scientific opinion on the safety of caffeine, providing advice on caffeine intakes, from all dietary sources that do not
EFSA Panel on Dietetic Products, Nutrition and Allergies (NDA)
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BMEMat, EarlyView.Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang +9 more
wiley +1 more source