Results 61 to 70 of about 168,979 (308)

The Taste of Caffeine [PDF]

Journal of Caffeine Research, 2017
Many people avidly consume foods and drinks containing caffeine, despite its bitter taste. Here, we review what is known about caffeine as a bitter taste stimulus. Topics include caffeine's action on the canonical bitter taste receptor pathway and caffeine's action on noncanonical receptor-dependent and -independent pathways in taste cells.
Rachel L, Poole, Michael G, Tordoff
openaire   +2 more sources

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

British Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden, Miriam G. Mooij, Matthijs de Hoog, Saskia N. de Wildt   +3 more
wiley   +1 more source

US parent perspectives on teen caffeine intake: An opportunity for health care provider guidance

Preventive Medicine Reports
Purpose: To explore parental knowledge and behaviors regarding their adolescent's intake of caffeine to provide context as to what guidance from health care providers could be helpful for families. Methods: Data were collected in February 2024 as part of
Sarah J. Clark, Acham Gebremariam, Sara Schultz, Lindsey Ewing, Susan J. Woolford   +4 more
doaj   +1 more source

Caffeine-mixed alcohol exposure in adolescence increases natural reward consumption and preference.

, 2016
Adolescent exposure to caffeine-mixed alcohol (15 mg/kg caffeine, 1.5 g/kg alcohol, A+C) or water (H2O) altered natural reward consumption and preference in adulthood (n = 6–8 per group).
Meridith T. Robins (3159948), Richard M. van Rijn (390178), Julie Lu (3159951)   +2 more
core   +1 more source

Clinical relevance of pharmacogenomic information for improving prescribing practices in acutely admitted older medical patients

British Journal of Clinical Pharmacology, EarlyView.
Aims Safe prescribing and effective medication review during acute hospitalization depends on accurate information about liver and kidney function because these organs are responsible for the elimination of most medications. While estimates for kidney function are widely used, comparable markers of hepatic drug‐metabolizing capacity are not routinely ...
Louise Westberg Strejby Christensen, Anne Kirstine Boas, Emilie Clausen, Nicoline Elers Koch, Anne Byriel Walls, Lotte Stig Nørgaard, Michael Asger Andersen, Anissa Aharaz, Rikke Lundsgaard Nielsen, Olivia Bornæs, Juliette Tavenier, Baker Nawfal Jawad, Helle Gybel Juul‐Larsen, Esben Iversen, Ove Andersen, Lona Louring Christrup, Kim Peder Dalhoff, Morten Baltzer Houlind   +17 more
wiley   +1 more source

The global extent of polypharmacy in neonatal intensive care: A systematic review

British Journal of Clinical Pharmacology, EarlyView.
Aims Pharmaceutical treatment in the neonatal intensive care unit (NICU) is challenging, with neonates often receiving multiple drugs during hospitalization. Given their physiological immaturity, polypharmacy raises concerns about potential adverse effects, drug–drug interactions and the risk of supratherapeutic or subtherapeutic treatment.
Mia Finserås Bretun, Ditte Resendal Gotfredsen, Aase Merethe Raddum, Charlotte Vermehren, Jón Þór Trærup Andersen, Ulrik Lausten‐Thomsen, Christina Gade   +6 more
wiley   +1 more source

Assessing the reinforcing effects of caffeine : the self-administrtion of caffeine by rats [PDF]

, 2009
Caffeine is the most widely consumed psychoactive drug, with the prevalence of use approaching 80% of the world's population. In stark contrast to most stimulants, caffeine is considered an innocuous agent with advantageous behavioral effects ...
NC DOCKS at The University of North Carolina Wilmington, Babalonis, Shanna   +1 more
core  

Effect of a mixture of caffeine and nicotinamide on the solubility of vitamin (B2) in aqueous solution [PDF]

, 2006
The effect of caffeine (CAF) and nicotinamide (NMD) on the solubility of a vitamin B2 derivative (FMN) has been evaluated for mixtures containing either a single hydrotrope (CAF or NMD) or the two hydrotropes simultaneously.
Davies, David B., Hernandez Santiago, A.A., Evstigneev, V.P., Evstigneev, M.P.   +3 more
core   +1 more source

Mitochondria‐endoplasmic reticulum organelle glue as maturation promoter for origination/dimensional dual‐cross cardiomyocytes

BMEMat, EarlyView.
Mitochondria‐endoplasmic reticulum contact sites (MERCS) are areas where the mitochondria and endoplasmic reticulum closely interact. In this study, we utilize synthetic organelle glues to artificially engineer MERCS for regulating cardiomyocyte development, through which the immature and chemo‐plasticity issues of undifferentiated cells are addressed.
Wei Tang, Hao Sun, Chenqi Duan, Jiajia Chang, Yuxing Wang, Ming Zhao, Huiyue Zhao, Shan Lu, Yang Yang, Da Huo   +9 more
wiley   +1 more source

Effects of Caffeine Consumption by Women and Men on the Outcome of In Vitro Fertilization.

, 2011
OBJECTIVE: The objective of this study was to estimate the association between caffeine consumption and in vitro fertilization (IVF) outcomes. METHODS: A total of 2474 couples were prospectively enrolled prior to undergoing their first cycle of IVF ...
Cramer, DW, Hornstein, MD, Ryan, LM, Daniel W. Cramer, Stacey A. Missmer, Mark D. Hornstein, Missmer, SA, Jamie H. Choi, Choi, JH, Louise M. Ryan   +9 more
core   +1 more source