Results 61 to 70 of about 164,322 (311)

The impact of daily caffeine intake on nighttime sleep in young adult men

open access: yesScientific Reports, 2021
Acute caffeine intake can delay sleep initiation and reduce sleep intensity, particularly when consumed in the evening. However, it is not clear whether these sleep disturbances disappear when caffeine is continuously consumed during daytime, which is ...
Janine Weibel   +9 more
doaj   +1 more source

Caffeine Enhances Osteoclast Differentiation from Bone Marrow Hematopoietic Cells and Reduces Bone Mineral Density in Growing Rats

open access: yes, 2012
Caffeine-containing beverage consumption has been associated with low bone mass and increased fracture risk in some, but not most, observational studies. The effects of caffeine on bone metabolism are still controversial.
LIU, SHING-HWA;CHEN, CHIN-LIANG;YANG, RONG-SEN;YEN, YUAN-PENG;TSAI, CHING-MIN   +1 more
core   +1 more source

Grandparent Prenatal Tobacco, Alcohol, Coffee, and Tea Consumption and Autism in the Third Generation

open access: yesAutism Research, EarlyView.
ABSTRACT Exogenous prenatal exposures may affect neurodevelopment across multiple generations. We investigated grandmother and grandfather smoking, alcohol, coffee, and tea consumption during pregnancy in relation to their grandchildren's risk of autism spectrum disorder (ASD).
Michelle Pearl   +6 more
wiley   +1 more source

Neuroprotective effect of caffeine in Alzheimer’s disease

open access: yes, 2023
AIM: This systematic review article aimed to clarify the effect of caffeine on AD and cognition by summarizing all the relevant research done on this topic METHOD: In the present review, we searched the Web of Science core collection and PubMed for ...
Faull, Richard   +3 more
core  

Pentoxifylline dose finding trial in preterm neonates with suspected late onset sepsis (PTX‐trial)

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim The aim of this study (PTX‐trial) is to determine the optimal dose of pentoxifylline (PTX) in preterm neonates (gestational age < 30 weeks) with (suspected) late onset sepsis (LONS). Methods The PTX‐trial is a prospective multicentre open‐label sequential dose‐optimization study with an adapted continual reassessment method.
Serife Kurul   +7 more
wiley   +1 more source

Salivary evaluation of young habitual caffeine consumers: biochemical and taste characteristics

open access: yesBrazilian Dental Science
Objective: Caffeine may be related to systemic effects, but information on sex differences and its influence on salivary characteristics is scarce. This study assessed the relationship between caffeine consumption, saliva and gustatory characteristics ...
Kelly Guedes de Oliveira Scudine   +6 more
doaj   +1 more source

Beyond the label: Rethinking off‐label drug use in paediatrics. Towards a scientifically grounded and safer future for paediatric pharmacotherapy

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Abstract Despite regulatory progress being made in the past two decades, off‐label drug use in paediatrics remains pervasive, with prevalence estimated between 3% and 97% of prescriptions across different clinical settings. Off‐label use—defined as prescribing outside the conditions described in the Summary of Product Characteristics (SmPC)—is often ...
Tjitske M. van der Zanden   +3 more
wiley   +1 more source

Development of a nalmefene formulation suitable for a community‐use auto‐injector

open access: yesBritish Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano   +6 more
wiley   +1 more source

US parent perspectives on teen caffeine intake: An opportunity for health care provider guidance

open access: yesPreventive Medicine Reports
Purpose: To explore parental knowledge and behaviors regarding their adolescent's intake of caffeine to provide context as to what guidance from health care providers could be helpful for families. Methods: Data were collected in February 2024 as part of
Sarah J. Clark   +4 more
doaj   +1 more source

Effect Of Caffeine On Exercise Performance: Current Review

open access: yesTürk Spor ve Egzersiz Dergisi, 2021
Caffeine is an ergogenic supplement that has been attracting attention in the sports community for many years. It has been proven in many studies that coffee consumption has a positive effect on exercise performance.
Yusuf Buzdağlı   +3 more
doaj  

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