Results 41 to 50 of about 164,322 (311)

Microfluidic Droplet Plate Preserving Single Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes Morphology and Function

open access: yesAdvanced Materials Technologies, EarlyView.
We introduce a novel method combining microfluidics, optogenetics, and human induced pluripotent stem cell (iPSC) technology to encapsulate single iPSC‐derived cardiomyocytes (iPSC‐CMs) in an optimal environment for functional characterization. This method enables direct genotype‐phenotype correlation for genetic studies and high‐throughput screening ...
Xiao‐Ting Wang   +7 more
wiley   +1 more source

Effect of a mixture of caffeine and nicotinamide on the solubility of vitamin (B2) in aqueous solution [PDF]

open access: yes, 2006
The effect of caffeine (CAF) and nicotinamide (NMD) on the solubility of a vitamin B2 derivative (FMN) has been evaluated for mixtures containing either a single hydrotrope (CAF or NMD) or the two hydrotropes simultaneously.
Davies, David B.   +3 more
core   +1 more source

Determining the Impact of Caffeine Concentrations on Betta splendens [PDF]

open access: yes, 2022
Caffeine, a naturally occurring chemical stimulant called trimethylxanthine, is commonly consumed by humans through various products and is becoming more widespread, and consequently, caffeine has appeared in aquatic environments around the world ...
Ryan, Cheng, Andrew, Lee, John , Heslar
core   +1 more source

Light‐Driven Quadrupedal Walking Biohybrid Robot With Antagonistic Muscle‐Rings and Inclined Joints

open access: yesAdvanced Robotics Research, EarlyView.
This work presents a light‐driven quadrupedal walking biohybrid robot powered by antagonistic muscle‐rings that achieve alternating walking gait. Optical training improved reproducibility of cultured muscle tissues, while caffeine treatment enhanced contractile force.
Shotaro Saito   +5 more
wiley   +1 more source

Caffeine From a Pharmaceutical Point of View

open access: yes, 2023
Caffeine is one of the most widely consumed psychoactive substances in the world due to its stimulating effects on central nervous system. Caffeine mainly exerts its effects through a non-selective antagonism of adenosine receptors in different systems ...
Lin, Fang-Chia
core  

Paternal Sperm Gnas‐ICR Epigenetic Programming Contributes to PPP‐Like Phenotypes in Female Offspring

open access: yesAdvanced Science, EarlyView.
A paternal glucocorticoid–sperm Gnas‐ICR axis is linked to ovarian endocrine programming in female offspring. Paternal preconception caffeine exposure elevates corticosterone, promotes sperm Gnas‐ICR hypermethylation, and is associated with ovarian Gnas upregulation, cAMP/PKA/CREB–StAR activation, enhanced estradiol synthesis, and PPP‐like phenotypes ...
Jing Huang   +4 more
wiley   +1 more source

Biodegradation of caffeine by whole cells of tea-derived fungi Aspergillus sydowii, Aspergillus niger and optimization for caffeine degradation

open access: yesBMC Microbiology, 2018
Background Pu-erh tea is a traditional Chinese tea and produced by natural solid-state fermentation. Several studies show that the natural microbiota influence caffeine level in pu-erh tea.
Binxing Zhou   +3 more
doaj   +1 more source

Possible Effects of the Presence of Common Household Chemicals in the Environment: The Growth of an Aquatic Bacterial Species on High Concentrations of Caffeine [PDF]

open access: yes, 2012
Caffeine is a prevalent chemical in the environment, often being found in aquatic ecosystems. Past studies have shown that some bacterial species can metabolize caffeine, but little research has been done to study the effect of different caffeine ...
Nikitin, Alexey G.   +3 more
core  

Nucleoside‐Modified mRNA Encoding Alpha‐Galactosidase A Ameliorates Fabry Disease Phenotypes in Human IPSC‐Derived Cardiomyocytes

open access: yesAdvanced Science, EarlyView.
Human iPSC‐derived Fabry cardiomyocytes exhibited broad transcriptional dysregulation, apoptosis, mitochondrial dysfunction, impaired reactive oxygen species handling, altered contractility, and abnormal calcium transient decay, potentially mediated by phospholamban hyperphosphorylation.
Malte Juchem   +24 more
wiley   +1 more source

The caffeine dilemma: unraveling the intricate relationship between caffeine use disorder, caffeine withdrawal symptoms and mental well-being in adults

open access: yesPublic Health Nutrition
Objective: This study aimed to explore the relationship between caffeine use disorder (CUD), caffeine withdrawal symptoms and the prevalence of depression, anxiety and stress (DASS) in adults.
Mahmut Bodur   +4 more
doaj   +1 more source

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