Results 31 to 40 of about 168,979 (308)

Extending Small‐Molecule Aptamer Discovery Principles to Protein Targets: Selection and Characterization of Green Fluorescent Protein Aptamers

open access: yesAngewandte Chemie, EarlyView.
Protein‐binding aptamers remain poorly understood compared to their small‐molecule counterparts. Using green fluorescent protein (GFP) variants as a tractable model system, we show how subtle changes in protein surface composition and divalent metal ions reshape aptamer selection, specificity, and binding.
Stefen Stangherlin   +8 more
wiley   +2 more sources

Induction of chromosome shattering by ultraviolet light and caffeine: The influence of different distributions of photolesions [PDF]

open access: yes, 1986
Cells of synchonized and of asynchronously growing cultures of a V79 Chinese hamster line were microirradiated with a low poweer laser-UV-microbeam of wavelength 257 nm.
Cremer, Thomas, Cremer, Christoph
core   +1 more source

Effects of chronic caffeine intake and withdrawal on neural activity assessed via resting-state functional magnetic resonance imaging in mice

open access: yesHeliyon, 2022
Caffeine is a psychoactive substance that not only improves wakefulness, but also slows the cognitive decline caused by aging. However, at present, there are no reports about the effects of caffeine withdrawal, including headaches and changes in brain ...
Mitsuki Rikitake   +11 more
doaj   +1 more source

Genome-wide association study of caffeine metabolites provides new insights to caffeine metabolism and dietary caffeine-consumption behavior. [PDF]

open access: yes, 2016
Caffeine is the most widely consumed psychoactive substance in the world and presents with wide interindividual variation in metabolism. This variation may modify potential adverse or beneficial effects of caffeine on health.
Völzke, Henry   +33 more
core   +3 more sources

Caffeine cue-reactivity: The impact of caffeine-related stimuli and expectancies on caffeine craving. [PDF]

open access: yes, 2019
Caffeine is consumed by approximately 90% of adults, yet its potential addictive properties have been understudied. Specifically, this study examined the impact caffeine cue reactivity and expectancy on caffeine craving and withdrawal.
Shephard, Aaron
core   +1 more source

Common questions and misconceptions about caffeine supplementation: what does the scientific evidence really show?

open access: yesJournal of the International Society of Sports Nutrition
Caffeine is a popular ergogenic aid that has a plethora of evidence highlighting its positive effects. A Google Scholar search using the keywords “caffeine” and “exercise” yields over 200,000 results, emphasizing the extensive research on this topic ...
Jose Antonio   +19 more
doaj   +1 more source

Rapid measurement of serum caffeine concentrations in acuteclinical settings

open access: yesToxicology Communications, 2021
The number of acute caffeine poisoning cases have increased in Japan. We can use serum caffeine concentrations to evaluate the severity of caffeine poisoning and determine whether or not we should perform hemodialysis. In this study, we sought to develop
Tomoki Hanazawa   +3 more
doaj   +1 more source

Caffeine and Theobromine

open access: yesJournal of Food Protection, 1990
Two components of cocoa powder, caffeine (1,3,7-trimethylxanthine) and theobromine (3,7-dimethylxanthine), were evaluated for their effect on growth of L. monocytogenes strain V7. Caffeine (0.5%) and theobromine (2.5%) were added singly or in combination to skim milk or a modified tryptose phosphate broth (MTPB), which were sterilized, inoculated to ...
Laura J, Pearson, Elmer H, Marth
openaire   +2 more sources

Microfluidic Droplet Plate Preserving Single Human Induced Pluripotent Stem Cell‐Derived Cardiomyocytes Morphology and Function

open access: yesAdvanced Materials Technologies, EarlyView.
We introduce a novel method combining microfluidics, optogenetics, and human induced pluripotent stem cell (iPSC) technology to encapsulate single iPSC‐derived cardiomyocytes (iPSC‐CMs) in an optimal environment for functional characterization. This method enables direct genotype‐phenotype correlation for genetic studies and high‐throughput screening ...
Xiao‐Ting Wang   +7 more
wiley   +1 more source

Light‐Driven Quadrupedal Walking Biohybrid Robot With Antagonistic Muscle‐Rings and Inclined Joints

open access: yesAdvanced Robotics Research, EarlyView.
This work presents a light‐driven quadrupedal walking biohybrid robot powered by antagonistic muscle‐rings that achieve alternating walking gait. Optical training improved reproducibility of cultured muscle tissues, while caffeine treatment enhanced contractile force.
Shotaro Saito   +5 more
wiley   +1 more source

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