Results 11 to 20 of about 267,134 (305)

Serum caffeine concentrations in preterm infants: a retrospective study

Scientific Reports, 2023
Therapeutic drug monitoring is generally unnecessary in caffeine treatment for apnea of prematurity, as serum caffeine concentrations in preterm infants are normally markedly lower than those at which caffeine intoxication occurs.
Masashiro Sugino, Toru Kuboi, Yuta Noguchi, Katsufumi Nishioka, Yoko Tadatomo, Nana Kawaguchi, Takaaki Sadamura, Akiko Nakano, Yukihiko Konishi, Kosuke Koyano, Shinji Nakamura, Hitoshi Okada, Susumu Itoh, Takashi Kusaka   +13 more
doaj   +1 more source

Caffeine for the Pharmacological Treatment of Apnea of Prematurity in the NICU: Dose Selection Conundrum, Therapeutic Drug Monitoring and Genetic Factors

Frontiers in Pharmacology, 2021
Caffeine citrate is the drug of choice for the pharmacological treatment of apnea of prematurity. Factors such as maturity and genetic variation contribute to the interindividual variability in the clinical response to caffeine therapy in preterm infants,
Jia-Yi Long, Jia-Yi Long, Hong-Li Guo, Xin He, Ya-Hui Hu, Ying Xia, Rui Cheng, Xuan-Sheng Ding, Feng Chen, Jing Xu   +9 more
doaj   +1 more source

Is it the Taste or the Buzz? Alexithymia, Caffeine, and Emotional Eating [PDF]

, 2019
BACKGROUND: Alexithymia, a relatively stable personality trait characterized by difficulties identifying and describing feelings and externally oriented thinking, has been linked to both substance use disorders and eating disorders.
Brown, Tamara, Lyvers, Michael, Thorberg, Fred Arne   +2 more
core   +1 more source

Caffeine affects the biological responses of human hematopoietic cells of myeloid lineage via downregulation of the mTOR pathway and xanthine oxidase activity [PDF]

, 2015
Correction of human myeloid cell function is crucial for the prevention of inflammatory and allergic reactions as well as leukaemia progression. Caffeine, a naturally occurring food component, is known to display anti-inflammatory effects which have ...
Abooali, Maryam, Berger, Steffen M., Casely-Hayford, Maxwell A., Fasler-Kan, Elizaveta, Gibbs, Bernhard F., Gonçalves Silva, Isabel, Prokhorov, Alexandr, Sumbayev, Vadim V., Yasinska, Inna M.   +8 more
core   +3 more sources

Caffeine and Adenosine [PDF]

Journal of Alzheimer's Disease, 2010
Caffeine causes most of its biological effects via antagonizing all types of adenosine receptors (ARs): A1, A2A, A3, and A2B and, as does adenosine, exerts effects on neurons and glial cells of all brain areas. In consequence, caffeine, when acting as an AR antagonist, is doing the opposite of activation of adenosine receptors due to removal of ...
Ribeiro, Joaquim A., Sebastião, Ana M
openaire   +3 more sources

Timing of Caffeine Therapy and Neonatal Outcomes in Preterm Infants: A Retrospective Study

International Journal of Pediatrics, 2016
Background. Caffeine is widely used to treat apnea of prematurity. Here, we evaluated the efficacy of early caffeine (1-2 DOL) in decreasing the incidence of adverse neonatal outcomes. Methods.
Ivan Hand, Nahla Zaghloul, Lily Barash, Rudolph Parris, Ulrika Aden, Hsiu-Ling Li   +5 more
doaj   +1 more source

Caffeine activates HOG-signalling and inhibits pseudohyphal growth in Saccharomyces cerevisiae

BMC Research Notes, 2023
Objective Caffeine has a wide range of effects in humans and other organisms. Caffeine activates p38 MAPK, the human homolog to the Hog1 protein that orchestrates the high-osmolarity glycerol (HOG) response to osmotic stress in the yeast Saccharomyces ...
Tarek Elhasi, Anders Blomberg
doaj   +1 more source

Effects of caffeine on cognitive and autonomic measures in heavy and light caffeine consumers [PDF]

, 2004
Caffeine effects on arousal and cognition were assessed in relation to habitual caffeine intake. After drinking either decaffeinated coffee or decaffeinated coffee plus 300 mg caffeine, 22 heavy caffeine consumers (HCCs) and 26 light caffeine consumers ...
Anderson, Andrews, Arnett, Barone, Beck, Beck, Berman, Bornstein, Boulenger, Bruce, Bruce, Bruce, Bättig, Bättig, Cameron, Charney, D'Amicis, Daly, Daly, Davidson, Deborah Matica, Drewe, Edwards, Erikson, Evans, Eysenck, Feldman, Foreman, Garrett, Gilbert, Hasenfratz, Heaton, Heishman, Henik, Hertz, Hindmarch, Hughes, James, James, Janine Brooks, Julien, Kenemans, Kenemans, Lane, Loke, Loke, Lyvers, Lyvers, Lyvers, Lyvers, Lyvers, Lyvers, Lyvers, MacLeod, Malloy, Maltzman, Mathew, Meyer, Michael Lyvers, Milner, Mountain, Nehlig, Newman, Osman, Patat, Phillips-Bute, Quinlan, Rees, Richardson, Riedel, Robelin, Rogers, Rogers, Rusted, Smith, Smith, Spielberger, SPSS Inc., Stelt, Stewart, Stuss, Till, Warburton, White, Zahn   +84 more
core   +1 more source

Impact of caffeine on myocardial perfusion reserve assessed by semiquantitative adenosine stress perfusion cardiovascular magnetic resonance

Journal of Cardiovascular Magnetic Resonance, 2019
Background Adenosine is used in stress perfusion cardiac imaging to reveal myocardial ischemia by its vasodilator effects. Caffeine is a competitive antagonist of adenosine.
Andreas Seitz, Philipp Kaesemann, Maria Chatzitofi, Stephanie Löbig, Gloria Tauscher, Raffi Bekeredjian, Udo Sechtem, Heiko Mahrholdt, Simon Greulich   +8 more
doaj   +1 more source

Caffeine. cognitive and physical performance enhancer or psychoactive drug? [PDF]

, 2015
Caffeine use is increasing worldwide. The underlying motivations are mainly concentration and memory enhancement and physical performance improvement. Coffee and caffeine-containing products affect the cardiovascular system, with their positive inotropic
Aromatario, Mariarosaria, Cappelletti, Simone, Piacentino, Daria, Sani, Gabriele   +3 more
core   +1 more source