Results 111 to 120 of about 262,566 (370)

Mechanochemical Strategies Applied to the Late‐Stage Modifications of Pharmaceutically Active Compounds

open access: yesAngewandte Chemie International Edition, Accepted Article.
This review explores the potential of mechanochemistry in the late‐stage modification of active pharmaceutical ingredients (APIs), offering a comprehensive analysis of methods designed to transform structurally complex molecular scaffolds. By examining the scope, efficiency, and mechanistic aspects of these approaches, the review highlights protocols ...
Johanna Templ, Lars Borchardt
wiley   +1 more source

Catechins and Caffeine Inhibit Fat Accumulation in Mice through the Improvement of Hepatic Lipid Metabolism

open access: yesJournal of Obesity, 2012
To elucidate the inhibiting mechanisms of fat accumulation by catechins, caffeine, and epigallocatechin gallate (EGCG), ICR mice were fed diets containing either 0.3% catechins or 0.1% EGCG and/or 0.05% caffeine for 4 weeks.
Chikako Sugiura   +5 more
doaj   +1 more source

Photoelectrochemical Iron(III) Catalysis for Late‐Stage C─H Fluoroalkylations

open access: yesAngewandte Chemie International Edition, EarlyView.
Efficient electrophotochemical C─H fluoroalkylation of complex bioactive substrates with abundant fluoroalkyl carboxylic acids employing an inexpensive iron(III) catalyst accompanied by hydrogen evolution reaction has been developed. Abstract Chemo‐ and site‐selective functionalization of complex molecules poses a fundamental challenge.
Vladimir Motornov   +8 more
wiley   +1 more source

Effects of Caffeine on Maximum Bench Press Repetitions [PDF]

open access: yes, 2011
The purpose of this research is to study the effects of caffeine on the maximum amount bench press repetitions performed. Blood pressure and heart rate will also be measured. This research is important because of the popular use of caffeine among college
Soller, Alex
core   +1 more source

Effects of caffeine on sleep quality and daytime functioning

open access: yesRisk Management and Healthcare Policy, 2018
Frances O’Callaghan,1 Olav Muurlink,2,3 Natasha Reid4 1School of Applied Psychology, Griffith Health, Griffith University, Southport, QLD, Australia; 2School of Business and Law, Central Queensland University, Brisbane, QLD, Australia; 3Griffith ...
O'Callaghan F, Muurlink O, Reid N
doaj  

Quantitative Analysis of Caffeine Levels in Local Coffee (Coffea sp) Powder on Dabo Island with UV-Vis Spectrophotometry

open access: yesBorneo Journal of Pharmacy, 2019
Coffee (Coffea sp) is the second-largest beverage consumed by people around the world whose process comes from the processing and extraction of coffee beans. Coffee has a chemical compound, one of which is caffeine. Caffeine is a crystal-shaped compound.
Sri Hainil   +2 more
doaj   +1 more source

Atomic Structures of Riboflavin (Vitamin B2) and its Reduced Form with Bond Lengths Based on Additivity of Atomic Radii [PDF]

open access: yesarXiv, 2008
It has been shown recently that chemical bond lengths, in general, like those in the components of nucleic acids, caffeine related compounds, all essential amino acids, methane, benzene, graphene and fullerene are sums of the radii of adjacent atoms constituting the bond.
arxiv  

Semi-supervised Sequential Generative Models [PDF]

open access: yesarXiv, 2020
We introduce a novel objective for training deep generative time-series models with discrete latent variables for which supervision is only sparsely available. This instance of semi-supervised learning is challenging for existing methods, because the exponential number of possible discrete latent configurations results in high variance gradient ...
arxiv  

Deep Supramolecular Language Processing for Co‐crystal Prediction

open access: yesAngewandte Chemie International Edition, Accepted Article.
Approximately 40% of marketed drugs exhibit suboptimal pharmacokinetic profiles. Co‐crystallization, where pairs of molecules form a multicomponent crystal, constitutes a promising strategy to enhance physicochemical properties without compromising pharmacological activity.
Rebecca Birolo   +5 more
wiley   +1 more source

Induction of chromosome shattering by ultraviolet light and caffeine: The influence of different distributions of photolesions [PDF]

open access: yes, 1986
Cells of synchonized and of asynchronously growing cultures of a V79 Chinese hamster line were microirradiated with a low poweer laser-UV-microbeam of wavelength 257 nm.
Barranco   +42 more
core   +1 more source

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