Caffeine causes most of its biological effects via antagonizing all types of adenosine receptors (ARs): A1, A2A, A3, and A2B and, as does adenosine, exerts effects on neurons and glial cells of all brain areas. In consequence, caffeine, when acting as an AR antagonist, is doing the opposite of activation of adenosine receptors due to removal of ...
Ribeiro, Joaquim A., Sebastião, Ana M
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On the Adsorption Mechanism of Caffeine on MAPbI3 Perovskite Surfaces: A Combined UMC--DFT Study [PDF]
Recently, it was experimentally shown that the performance and thermal stability of the perovskite MAPbI$_3$ were improved upon the adsorption of a molecular layer of caffeine. In this work, we used a hybrid methodology that combines Uncoupled Monte Carlo (UMC) and Density Functional Theory (DFT) simulations to carry out a detailed and comprehensive ...
arxiv +1 more source
International society of sports nutrition position stand: caffeine and exercise performance
Following critical evaluation of the available literature to date, The International Society of Sports Nutrition (ISSN) position regarding caffeine intake is as follows: Supplementation with caffeine has been shown to acutely enhance various aspects of ...
Nanci S. Guest+13 more
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Caffeine consumption within British fencing athletes
The ergogenic effects of caffeine are well documented, yet despite the potential benefits of supplementation, there is a lack of understanding of caffeine habits and supplementation within fencing.
George Bowra Morris+2 more
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Genetics of caffeine consumption and responses to caffeine [PDF]
Caffeine is widely consumed in foods and beverages and is also used for a variety of medical purposes. Despite its widespread use, relatively little is understood regarding how genetics affects consumption, acute response, or the long-term effects of caffeine.This paper reviews the literature on the genetics of caffeine from the following: (1) twin ...
Harriet de Wit+2 more
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Caffeine Inhibits EGF-Stimulated Trophoblast Cell Motility through the Inhibition of mTORC2 and Akt. [PDF]
Impaired trophoblast invasion is associated with pregnancy disorders such as early pregnancy loss and preeclampsia. There is evidence to suggest that the consumption of caffeine during pregnancy may increase the risk of pregnancy loss; however, little is
Alison E. Wallace+46 more
core +1 more source
Excess caffeine exposure impairs eye development during chick embryogenesis [PDF]
Caffeine has been an integral component of our diet and medicines for centuries. It is now known that over consumption of caffeine has detrimental effects on our health, and also disrupts normal foetal development in pregnant mothers.
Cheng, Xin+6 more
core +2 more sources
Caffeine activates HOG-signalling and inhibits pseudohyphal growth in Saccharomyces cerevisiae
Objective Caffeine has a wide range of effects in humans and other organisms. Caffeine activates p38 MAPK, the human homolog to the Hog1 protein that orchestrates the high-osmolarity glycerol (HOG) response to osmotic stress in the yeast Saccharomyces ...
Tarek Elhasi, Anders Blomberg
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Caffeine Modulates the Dynamics of DODAB Membranes: Role of the Physical State of the Bilayer [PDF]
Caffeine (1,3,7-trimethylxanthine), an ingredient of coffee, is used worldwide as a psychostimulant, antioxidant, and adjuvant analgesic. To gain insights into the action mechanism of caffeine, we report on its effects on the phase behaviour and microscopic dynamics of a dioctadecyldimethylammonium bromide (DODAB) lipid membrane, as studied ...
arxiv +1 more source
Serum caffeine concentrations in preterm infants: a retrospective study
Therapeutic drug monitoring is generally unnecessary in caffeine treatment for apnea of prematurity, as serum caffeine concentrations in preterm infants are normally markedly lower than those at which caffeine intoxication occurs.
Masashiro Sugino+13 more
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