Results 191 to 200 of about 60,320 (281)

Menstrual cycle effects on sex differences in motor control during dynamic balance perturbations

Experimental Physiology, EarlyView.
Abstract This study investigated sex differences in neuromuscular responses during dynamic balance perturbations and isometric maximal voluntary contractions (IMVCs) by examining if menstrual cycle (MC) phase and the fluctuations in endogenous hormones influence the observation of sex differences.
Samuli Nevanperä, Ritva S. Mikkonen, Simon Walker, Jarmo M. Piirainen   +3 more
wiley   +1 more source

Microdosing psilocybin for major depressive disorder: study protocol for a phase II double-blind placebo-controlled randomised partial crossover trial. [PDF]

BJPsych Open
Beidas Z, Ragnhildstveit A, Blackman A, Anderson T, Fewster E, Syed OA, Sobolenko V, Kanca IK, Jaglinska M, Son T, Farb N, Petranker R.   +11 more
europepmc   +1 more source

On‐feet isometric bracing maintains cerebral arterial blood velocity during lower body negative pressure via preload augmentation

Experimental Physiology, EarlyView.
Abstract Orthostatic stress reduces venous return and stroke volume (SV), risking cerebral hypoperfusion despite autonomic compensation. Although lower‐limb counterpressure manoeuvres improve cerebral perfusion in upright posture, their effects on cerebral blood velocity (CBV) during lower‐body negative pressure (LBNP) and the associated mechanisms are
Jun Sugawara, Marina Fukuie, Tsubasa Tomoto, Takashi Tarumi, Ai Hirasawa, Shigeki Shibata   +5 more
wiley   +1 more source

Cardiac remodelling in type 2 diabetes: Pathophysiological mechanisms and opportunities for multiscale computational modelling and simulation

The Journal of Physiology, EarlyView.
Abstract figure legend Overview of multiscale cardiac remodelling in type 2 diabetes and how to model and simulate these changes using a human‐based, multiscale computational framework. Cardiac remodelling in type 2 diabetes occurs at ionic channel, protein, cellular, tissue and whole‐organ level, affecting the electrophysiological function, mechanical
Ambre Bertrand, Jakub Tomek, Blanca Rodriguez   +2 more
wiley   +1 more source

Efficacy and safety of intravenously applied caffeine augmentation in electroconvulsive therapy. [PDF]

Neurosci Appl
Ridder MD, Ulrich S, Vettermann R, Liwinski T, Deuring G, Sarlon J, Brühl A, Schneider E.   +7 more
europepmc   +1 more source

Blebbistatin reduces calcium buffering in cardiomyocytes: Consequences for cellular electrophysiology

The Journal of Physiology, EarlyView.
Abstract figure legend Blebbistatin reduces Ca2+ buffering in induced pluripotent stem cell‐derived atrial cardiomyocytes. Blebbistatin, a widely used excitation–contraction uncoupling agent, decreases calcium (Ca2+) buffer affinity (increased buffer dissociation constant), leading to elevated diastolic Ca2+ levels, increased sarcoplasmic reticulum Ca2+
Izzatullo Sobitov, Katharina Ritzenhoff, Marie Gaulrapp, Lea Becker, Aiste Liutkute, Fitzwilliam Seibertz, Funsho E. Fakuade, Fleur E. Mason, Niels Voigt   +8 more
wiley   +1 more source

Coffee intake is associated with telomere length in severe mental disorders. [PDF]

BMJ Ment Health
Mlakar V, Di Forti M, Halff EF, Srivastava DP, Akkouh I, Djurovic S, Martin-Ruiz C, Quintana DS, Birkenæs V, Steen NE, Ormerod MB, Andreassen OA, Aas M.   +12 more
europepmc   +1 more source

Mechanisms underlying local Ca2+ signalling differences between right and left atrial myocytes at normal and increased frequencies

The Journal of Physiology, EarlyView.
Abstract figure legend Left atrial myocytes have TAT‐associated faster Ca2+ release but are more prone to maladaptation at higher frequencies due to weaker peripheral SR Ca2+ uptake and smaller trigger Ca2+ current. Abstract Changes in heart rate affect Ca2+ signalling and contractility in ventricular muscle, but the effects on atrial Ca2+ signalling ...
Joon‐Chul Kim, Hieu Trong Huynh, Phuong Kim Luong, Tran Nguyet Trinh, Yixuan Wu, Eleonora Grandi, Sun‐Hee Woo   +6 more
wiley   +1 more source

The effect of caffeine use in the relationship between gaming and sleep in adolescents: A mediation analysis. [PDF]

J Behav Addict
Park JJ, Han X, Potenza MN, Zhao Y.
europepmc   +1 more source

Acute intermittent hypercapnic hypoxia augments left ventricular contractility

The Journal of Physiology, EarlyView.
Abstract figure legend Twenty‐four healthy adults were studied to determine the effects of an acute session of 40 min of intermittent hypercapnic hypoxia on cardiac performance. Cardiac function was assessed via echocardiography at rest and during graded stages of lower‐body negative pressure before and after the intervention to quantify load ...
Scott F. Thrall, Alex M. Williams, Philip J. Millar, Megan L. Lance, Brooke M. Shafer, Conan L. H. Shing, Jordan D. Bird, Christopher R. West, Glen E. Foster   +8 more
wiley   +1 more source