Results 151 to 160 of about 33,889 (177)
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3 Biotech
Cytotoxic-associated gene A (CagA) is a key virulence factor of Helicobacter pylori, associated with gastric ulcers and stomach cancer. The bacterium employs a Cag-type IV secretion system for translocation of CagA into the host cells. This study investigates the impact of CagA antibodies on CagA translocation into gastric epithelial cells in vitro ...
Swagata Sain +2 more
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Cytotoxic-associated gene A (CagA) is a key virulence factor of Helicobacter pylori, associated with gastric ulcers and stomach cancer. The bacterium employs a Cag-type IV secretion system for translocation of CagA into the host cells. This study investigates the impact of CagA antibodies on CagA translocation into gastric epithelial cells in vitro ...
Swagata Sain +2 more
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Gut, 2002
The prevalence of Helicobacter pylori colonisation in populations in developed country has been declining, as shown by community based serological surveys of adults in Vammala, Finland in 1973 and 1994. In this study, we determined whether the proportion of subjects colonised by cagA(+) or cagA(-) H pylori strains has changed as the overall prevalence ...
G I, Perez-Perez +7 more
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The prevalence of Helicobacter pylori colonisation in populations in developed country has been declining, as shown by community based serological surveys of adults in Vammala, Finland in 1973 and 1994. In this study, we determined whether the proportion of subjects colonised by cagA(+) or cagA(-) H pylori strains has changed as the overall prevalence ...
G I, Perez-Perez +7 more
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SagA of CagA in Helicobacter pylori pathogenesis
Current Opinion in Microbiology, 2008Much attention has recently been given to the role of the Helicobacter pylori CagA protein, the only as yet identified H. pylori protein that is delivered into the host gastric epithelial cells by a type IV secretion system, in the development of H. pylori-associated diseases, including gastric carcinoma.
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Dyspepsia Is Associated With Caga-Positive Helicobacter Pylori
American Journal of Gastroenterology, 2000The role of Helicobacter pylori in nonulcer dyspepsia is controversial. Speculation has arisen that only strains of H. pylori carrying the CagA virulence factor are important in the development of dyspepsia. The objective of this study was to determine whether nonulcer dyspepsia correlated with CagA-positive H.
D B, Nelson +5 more
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Helicobacter pylori CagI is associated with the stability of CagA
Microbial Pathogenesis, 2016The type Ⅳ secretion system (T4SS) of H. pylori encoded by cag pathogenicity island mediates the injection of the toxin CagA, which is considered as a paradigm for bacterial carcinogenesis. T4SS is generally composed of a set of proteins, the majority of which still remain unclear. In this study, we have identified CagI, one of the T4SS proteins, which
Hua, Wang +6 more
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Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences, 2005
To construct a prokaryotic expression system of a fragment from Helicobacter pylori cagA gene and to detect the CagA positive Helicobacter pylori (CagA(+) H. pylori) and its antibody with the recombinant protein cagA 1.H.pylori isolates were obtained from biopsy specimens of 156 patients with gastric diseases. PCR method was used to detect frequency of
Yuan, Wang, Yi-hui, Luo, Jie, Yan
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To construct a prokaryotic expression system of a fragment from Helicobacter pylori cagA gene and to detect the CagA positive Helicobacter pylori (CagA(+) H. pylori) and its antibody with the recombinant protein cagA 1.H.pylori isolates were obtained from biopsy specimens of 156 patients with gastric diseases. PCR method was used to detect frequency of
Yuan, Wang, Yi-hui, Luo, Jie, Yan
openaire +1 more source