Results 1 to 10 of about 21,236 (243)

Helicobacter pylori infection: is there circulating vacuolating cytotoxin A or cytotoxin-associated gene A protein? [PDF]

Gut Pathogens, 2022
Background Helicobacter pylori infection is a well-recognized cause of gastric diseases, including chronic gastritis, peptic ulcer, and gastric cancer.
Ichiro Imoto, Satoko Oka, Masaki Katsurahara, Misaki Nakamura, Taro Yasuma, Junko Akada, Corina N. D’Alessandro-Gabazza, Masaaki Toda, Noriyuki Horiki, Esteban C. Gabazza, Yoshio Yamaoka   +10 more
doaj   +4 more sources

A novel role for Helicobacter pylori cytotoxin-associated gene A in negative regulation of autophagy in human gastric cells [PDF]

BMC Gastroenterology, 2023
Background Autophagy plays an important role in carcinogenesis and tumor progression in many cancers, including gastric cancer. Cytotoxin-associated gene A (CagA) is a well-known virulent factor in Helicobacter pylori (H.
Akihiko Sakatani, Yoshito Hayashi, Hirotsugu Saiki, Minoru Kato, Ryotaro Uema, Takanori Inoue, Keiichi Kimura, Shunsuke Yoshii, Yoshiki Tsujii, Shinichiro Shinzaki, Hideki Iijima, Tetsuo Takehara   +11 more
doaj   +4 more sources

Cytotoxin-associated gene-A-seropositivity and Interleukin-1 polymorphisms influence adverse cardiovascular events [PDF]

International Journal of Cardiology: Heart & Vasculature, 2020
Aims: Although the bacterial virulent factor of cytotoxin-associated gene-A (CagA)-seropositivity and the host genetic factors of interleukin (IL)-1 polymorphisms have been suggested to influence Helicobacter pylori (HP) -related diseases, the underlying
Noriaki Tabata, Daisuke Sueta, Yuichiro Arima, Ken Okamoto, Takashi Shono, Shinsuke Hanatani, Seiji Takashio, Kentaro Oniki, Junji Saruwatari, Kenji Sakamoto, Koichi Kaikita, Jan-Malte Sinning, Nikos Werner, Georg Nickenig, Yutaka Sasaki, Toshihiro Fukui, Kenichi Tsujita   +16 more
doaj   +4 more sources

A cross-sectional study on molecular detection of Helicobacter pylori cytotoxin-associated gene A and 16SrRNA gene from gastric biopsy specimens [PDF]

Journal of Global Infectious Diseases, 2021
Introduction: The aim of the study is relative proportion of cytotoxin-associated gene A (cagA) virulence marker in Helicobacter pylori isolates and gastric biopsy samples by polymerase chain reaction (PCR).
Manjula A Vagarali, Sharada C Metgud, Hema Bannur, Suneel S Dodamani   +3 more
doaj   +4 more sources

Clinical significance of serum Helicobacter pylori antibody cytotoxin-associated gene A levels in patients with unstable angina [PDF]

European Journal of Medical Research
Objectives We investigated the clinical significance of serum Helicobacter pylori cytotoxin-associated gene A (CagA) antibody levels in 768 patients with unstable angina (UA). Methods Serum CagA levels were measured using ELISA.
Haizhen Jia, Huajun Fan, Jinhe Zhao, Jun Peng, Yunhong Pan, Hongyan Peng   +5 more
doaj   +4 more sources

Association of endothelial dysfunction and cytotoxin-associated gene A-positive Helicobacter pylori in patients with cardiac syndrome X [PDF]

Biomedical Journal, 2016
Existence of coronary endothelial dysfunction has been demonstrated in patients with cardiac syndrome X (CSX). In addition, Helicobacter pylorus (H. pylori) has been associated with CSX. We aimed to assess the possible association of endothelial dysfunction and cytotoxin-associated gene A-positive H.
Alireza Shirpoor, Yousef Rasmi, Ehsan Saboory   +2 more
exaly   +5 more sources

Helicobacter Pylori Virulence Factor Cytotoxin-Associated Gene A (CagA) Induces Vascular Calcification in Coronary Artery Smooth Muscle Cells [PDF]

International Journal of Molecular Sciences, 2023
Sven-Christian Pawelzik, Robin Hofmann, Magnus Back   +2 more
exaly   +2 more sources

Research progress in the relationship between EPIYA motif and Helicobacter pylori infection-associated gastropathy [PDF]

Xin yixue, 2023
Helicobacter pylori （Hp） is a major human pathogen. Hp infection will cause a series of gastrointestinal diseases， such as chronic gastritis， peptic ulcer and gastric cancer， etc.
Feng Fujuan, Shao Huijuan, Jiang Jingjing, Yu Xiaohui, Zheng Xiaofeng, Zhang Jiucong
doaj   +1 more source

Campylobacter jejuni Cytolethal Distending Toxin C Exploits Lipid Rafts to Mitigate Helicobacter pylori-Induced Pathogenesis

Frontiers in Cell and Developmental Biology, 2021
Helicobacter pylori infection is associated with several gastrointestinal diseases, including gastritis, peptic ulcer, and gastrointestinal adenocarcinoma.
Jia-Yin Yeh, Hwai-Jeng Lin, Hwai-Jeng Lin, Chia-Jung Kuo, Chia-Jung Kuo, Chun-Lung Feng, Chun-Lung Feng, Chia-Huei Chou, Chia-Huei Chou, Chia-Der Lin, Chia-Der Lin, Hui-Yu Wu, Chen-Yi Li, Cheng-Hsun Chiu, Cheng-Hsun Chiu, Cheng-Hsun Chiu, Chih-Ho Lai, Chih-Ho Lai, Chih-Ho Lai, Chih-Ho Lai   +19 more
doaj   +1 more source

Prevalence of Specific Helicobacter Pylori cagA, vacA, iceA, ureC Genotypes and its Clinical Relevance in the Patients with Acid-Peptic Diseases [PDF]

Journal of Clinical and Diagnostic Research, 2017
Introduction: Virulent markers of H. pylori, the vacuolating cytotoxin (vacA), cytotoxin-associated gene A (cagA), induced by contact with epithelium factor antigen (iceA gene) and the urease C gene (ureC) may plays a major role in determining the ...
Himani Bhardwaj Pandya, Harihar Hardas Agravat, Jagdish Shantilal Patel   +2 more
doaj   +1 more source