Results 11 to 20 of about 21,236 (243)

Cytotoxin-associated gene A increases carcinogenicity of in colorectal adenoma [PDF]

The International Journal of Biological Markers, 2020
Objective: This study aimed to investigate the correlation of Helicobacter pylori (Hp) infection with disease risk and severity of colorectal adenoma, also to explore the association of cytotoxin-associated gene A (CagA) positive (CagA + )- Hp infection ...
Heng Zhang, Yusheng Liao, Hongfeng Zhang, Jie Wu, Dan Zheng, Zhitao Chen   +5 more
doaj   +3 more sources

Cryptotanshinone inhibits cytotoxin-associated gene A-associated development of gastric cancer and mucosal erosions. [PDF]

World J Gastrointest Oncol, 2021
Approximately 90% of new cases of noncardiac gastric cancer (GC) are related to Helicobacter pylori (H. pylori), and cytotoxin-associated gene A (CagA) is one of the main pathogenic factors. Recent studies have shown that the pharmacological effects of cryptotanshinone (CTS) can be used to treat a variety of tumors.
Chen ZM, Hu J, Xu YM, He W, Meng L, Huang T, Ying SC, Jiang Z, Xu AM.   +8 more
europepmc   +3 more sources

The Relationship between Gastroduodenal Pathologies and Helicobacter pylori cagL (Cytotoxin-Associated Gene L) Polymorphism. [PDF]

Turk J Gastroenterol, 2023
Background: The polymorphisms in the region between 58 and 62 amino acids of the 194-amino acid CagL protein (CagL hypervariable motif) affect the binding affinity of CagL to integrin α5β1 (ITGA5B1) receptor in host epithelial cells and have an effect on the development of various gastrointestinal diseases.
Özbey D, Demiryas S, Akkuş S, Kepil N, Dinç HÖ, Gareayaghi N, Demirci M, Kurt EA, Uysal Ö, Sarıbaş S, Tokman HB, Kocazeybek B.   +11 more
europepmc   +4 more sources

Helicobacter pylori Virulence Factor Cytotoxin-Associated Gene A (CagA)-Mediated Gastric Pathogenicity. [PDF]

Int J Mol Sci, 2020
Helicobacter pylori causes persistent infection in the gastric epithelium of more than half of the world’s population, leading to the development of severe complications such as peptic ulcer diseases, gastric cancer, and gastric mucosa-associated lymphoid tissue (MALT) lymphoma.
Ansari S, Yamaoka Y.
europepmc   +4 more sources

The frequency of Anti- Cytotoxin associated Gene A (CagA) antibody in Golestan province of Iran

مجله دانشگاه علوم پزشکی گرگان, 2010
Background and Objective: Helicobacter pylori (H.pylori) with positive Cytotoxin associated Gene A (CagA) have higher potential for pathogenesis. Cytotoxin associated Gene A (CagA) accelerate the pathogenecity of bacteria due to cytotoxin production ...
Bagheri H (MSc), Ghaesemi Kebria F (MSc), Semnani Sh (MD), Livani S (BSc), Rafiei S (MD, MPH), Behnampour N (MSc), Ghaemi E (PhD)   +6 more
doaj   +1 more source

The Cytotoxin-Associated Gene A (CagA) of Helicobacter pylori: the Paradigm of an Oncogenic Virulence Factor [PDF]

Журнал Сибирского федерального университета: Серия Биология, 2017
Helicobacter pylori is a microaerophilic, spiral-shaped and gram-negative microorganism that produces various virulence factors such as CagA, VacA, urease, and host cells adhesins, which in a synchronous concert, allow H.
Alfiia I. Iunusova, Irina S. Litvinova, Polina A. Karpenok, Abolghasem Tohidpour   +3 more
doaj   +8 more sources

The Relation of Cytotoxin-Associated Gene-A Seropositivity with Vitamin B12 Deficiency in Helicobacter pylori-Positive Patients. [PDF]

Biomed Res Int, 2019
Background and Aim. As a worldwide infectious bacterium, H. pylori leads to stomach pathologies such as gastritis, peptic ulcer, gastric cancer, MALToma, and various extragastric manifestations. In our study, we aimed to investigate the association between serum vitamin B12 level and cytotoxin-associated gene-A (CagA) seropositivity, which is one of ...
Ulasoglu C, Temiz HE, Sağlam ZA.
europepmc   +3 more sources

Cytotoxin-Associated Gene-A–Positive Helicobacter pylori Strains Are Associated With Atherosclerotic Stroke [PDF]

Circulation, 2002
Background — It is uncertain whether Helicobacter pylori is associated with ischemic syndromes and whether this association is mediated by the induction of atherosclerosis.
PIETROIUSTI, ANTONIO, DIOMEDI, MARINA, Silvestrini, M, Cupini, LM, Luzzi, I, Gomez Miguel, MJ, Bergamaschi, A, MAGRINI, ANDREA, Carrabs, T, Vellini, M, GALANTE, ALBERTO   +10 more
openaire   +4 more sources

Prevalence of Helicobacter pylori vacA, cagA, cagE1, cagE2, dupA and oipA Genotypes in Patients With Gastrointestinal Diseases

Acta Medica Iranica, 2020
Background Helicobacter pylori (H. pylori) is a bacterium resides in the human stomach which is associated with gastroduodenal diseases. We investigate the prevalence of cagA, vacA, oipA, cagE1, cagE2 and dupA genotypes in H.
Ali badamchi
doaj   +1 more source

Relationship Between Helicobacter pylori IgG Seroprevalence and the Immune Response to Poliovirus Vaccine Among School-Age Children From a Population With Near-Universal Immunity Level

Frontiers in Medicine, 2022
ObjectivesTo examine the association between Helicobacter pylori seroprevalence and serum pepsinogens (PGs) as markers of gastric inflammation), with high neutralizing antibody titers to poliovirus type 1 and 3 vaccine strains among children age 3–4 ...
Layaly Badran Abu Zher, Merav Weil, Eias Kassem, Nael Elias, Myron M. Levine, Khitam Muhsen   +5 more
doaj   +1 more source