Results 41 to 50 of about 21,236 (243)
Saudi Medical Journal, 2012 OBJECTIVE: To detect the presence of virulence markers cytotoxin-associated (cagA) and vacuolating cytotoxin-associated (vacA) genes in gastric biopsy specimens of patients with gastroduodenal disorders. METHODS: This study was conducted at the Department of Pathology, King Khalid University Hospital, Riyadh, Kingdom of Saudi Arabia between March 2008 ...
openaire +2 more sources
Effect and mechanism of CagA on miR-142-3p expression regulation in gastric cancer cells
Zhongguo gonggong weisheng, 2022 Objective Cytotoxin associated protein A (CagA), the main virulence factor of Helicobacter pylori (Hp), plays an important role in the occurrence and development of gastric cancer.
Lei-lei WU, Fei JIANG, Xiao-wei CHEN
doaj +1 more source
Prevalence of the Helicobacter pylori in the tonsils and adenoids
Brazilian Journal of Otorhinolaryngology, 2015 INTRODUCTION: There is an ongoing debate about the existence and effects of Helicobacter pylori (Hp) in adenotonsillar tissue. OBJECTIVE: A clinical study was conducted to assess the existence of Hp in the adenoid and/or adenotonsillar tissues, which ...
Tuba Bayindir +5 more
doaj +1 more source
PLoS ONE, 2012 Helicobacter pylori (HP) is a bacterium that colonizes the human stomach and can establish a long-term infection of the gastric mucosa. Persistent Hp infection often induces gastritis and is associated with the development of peptic ulcer disease, atrophic gastritis, and gastric adenocarcinoma.
Cosmeri Rizzato +8 more
openaire +4 more sources
Zdorovʹe Rebenka, 2012 The article deal with study of lymphocyte-macrophage link of the gastric mucosa local immunity in Hр-associated chronic gastritis, taking into account the presence of the cytotoxin-associated gene A (CagA) Hр through a standard morphological examination ...
O.Ye. Abaturov +3 more
doaj +1 more source
NUST Journal of Natural Sciences, 2021 Helicobacter pylori (H. pylori) has evolved significant regulatory mechanisms in order to acclimatize in extreme gastric environment of human beings. The virulence machinery of H.
Gul Sanober +7 more
doaj +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Primary cutaneous anaplastic large cell lymphoma (pcALCL) is a rare pediatric CD30‐positive T‐cell lymphoproliferative disorder with an excellent prognosis, but its genomic drivers are poorly defined. We report three children with skin‐limited disease demonstrating striking molecular heterogeneity, including NPM::ALK, NUP214::FRK, and a novel ...
Shoshana Greenberger +7 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Background Fertility preservation (FP) is increasingly integrated into the care of pediatric patients exposed to gonadotoxic therapy or conditioning for hematopoietic stem cell transplantation (HSCT), yet perioperative data in infants and toddlers remain scarce.
Kerstin Saalabian +13 more
wiley +1 more source
Pediatric Blood &Cancer, EarlyView.ABSTRACT Objectives The association between exposure to dinutuximab beta (DB) and event‐free survival (EFS) or overall survival (OS) of neuroblastoma patients was assessed using data collected during three clinical trials (five cohorts). Methods A systematic review (March 2026) was conducted to identify relevant studies (prospective; registered DB ...
Przemysław Holko +19 more
wiley +1 more source
Natural Killer Cells in Paediatric Soft Tissue Sarcomas: A Systematic Review
Pediatric Blood &Cancer, EarlyView.ABSTRACT Paediatric soft tissue sarcomas (pSTS) are a rare and heterogeneous group of malignant tumours arising in tissues of mesenchymal origin. The role of natural killer (NK) cells in pSTS remains poorly understood, with evidence fragmented across small preclinical studies and early‐phase clinical trials.
Raya Dean +7 more
wiley +1 more source