Results 31 to 40 of about 21,236 (243)

Syzygium aromaticum L.: Traditional herbal medicine against cagA and vacA toxin genes-producing drug resistant Helicobacter pylori

Journal of Traditional and Complementary Medicine, 2020
The Pan-Drug Resistant (PDR), Helicobacter pylori remains an intractable challenge in public health worldwide and this pathogenicity is mainly due to the presence of a cytotoxin-associated gene A (CagA) and vacuolating cytotoxin A (VacA).
Wagih A. El-Shouny, Sameh S. Ali, Hegazy M. Hegazy, Manar K. Abd Elnabi, Asmaa Ali, Jianzhong Sun   +5 more
doaj   +1 more source

Mutation of cytotoxin-associated gene A affects expressions of antioxidant proteins of Helicobacter pylori

World Journal of Gastroenterology, 2009
To determine if disruption of the cagA gene of Helicobacter pylori (H pylori) has an effect on the expression of other proteins at proteome level.Construction of a cagA knock out mutant Hp27_Delta cagA (cagA(-)) via homologous recombination with the wild-type strain Hp27 (cagA(+)) as a recipient was performed.
Zhi-Gang, Huang, Guang-Cai, Duan, Qing-Tang, Fan, Wei-Dong, Zhang, Chun-Hua, Song, Xue-Yong, Huang, Rong-Guang, Zhang   +6 more
openaire   +2 more sources

Serum 8 Hydroxydeoxyguanosine and Cytotoxin Associated Gene A as Markers for Helicobacter pylori Infection

Asian Pacific Journal of Cancer Prevention, 2015
Helicobacter pylori (H.pylori) is associated with chronic gastritis, peptic ulcers, gastric adenocarcinomas and mucosa associated tissue lymphomas. Cytotoxin associated gene A (CagA) is one of the virulence factors of H.pylori. It is hypothesized that reactive oxygen species (ROS) play roles in H.pylori associated disease especially in development of ...
Abdullah Ozgur, Yeniova, Metin, Uzman, Ayse, Kefeli, Sebahat, Basyigit, Naim, Ata, Kursat, Dal, Servet, Guresci, Yasar, Nazligul   +7 more
openaire   +3 more sources

Association Between Cerebral Ischemia and Cytotoxin-Associated Gene-A–Bearing Strains of Helicobacter pylori [PDF]

Stroke, 2004
Background and Purpose— Studies on Helicobacter pylori infection and risk of ischemic stroke yielded variable results. Infection with more virulent H. pylori strains, such as cytotoxin-associated gene-A (CagA)–bearing strains, may be of particular ...
Michael R, Preusch, Armin J, Grau, Florian, Buggle, Christoph, Lichy, Jan, Bartel, Carmen, Black, Jochen, Rudi   +6 more
openaire   +2 more sources

Helicobacter pylori and Its Role in Gastric Cancer

Microorganisms, 2023
Gastric cancer is a challenging public health concern worldwide and remains a leading cause of cancer-related mortality. The primary risk factor implicated in gastric cancer development is infection with Helicobacter pylori. H.
Victor E. Reyes
doaj   +1 more source

Mutation of the cytotoxin-associated cagA gene does not affect the vacuolating cytotoxin activity of Helicobacter pylori [PDF]

Infection and Immunity, 1994
Helicobacter pylori now is recognized as an etiological agent in chronic superficial gastritis and peptic ulcer disease. Although only about 60% of H. pylori isolates produce an immunodominant 128-kDa antigen (CagA; cytotoxin-associated gene product), virtually all H. pylori-infected patients with duodenal ulceration develop a serologic response to the
M K, Tummuru, T L, Cover, M J, Blaser
openaire   +2 more sources

Modulation of Host Cell Signal Transduction Pathways by Helicobacter Pylori Infection

Canadian Journal of Gastroenterology, 2005
Bacterial pathogens modulate host cell signal transduction responses to establish infection and cause disease. The purpose of the present summary, first presented at the Canadian Helicobacter Study Group meeting, is to discuss current knowledge of ...
Peter JM Ceponis, Nicola L Jones
doaj   +1 more source

Cytotoxin Associated Gene A+ Helicobacter pylori Infection is Related with Endothelial Dysfunction in Normotensive Individuals

Kosuyolu Kalp Dergisi, 2014
Giriş: Sitotoksin ilişkili A genli Helicobacter pylori (SİAGHP), en çok virülansı olan H. pylori tipidir ve halen endotelyal disfonksiyon ile ilişkisi belirsizdir. Bu nedenle biz SİAGHP’nin endotelyal bağımlı dilatasyon üzerine etkilerini ve C-reaktif protein (CRP) düzeyleri ile ilişkisini normotansif bireylerde araştırdık.
AKYÜZ, Aydın, METE, Rafet, ORAN, Mustafa, ALPSOY, Şeref, AKKOYUN, Dursun Çayan, DEĞİRMENCİ, Pelin Osanmaz, AVCI, Okan   +6 more
openaire   +4 more sources

Genotyping of Helicobacter pylori Virulence Genes cagA and vacA: Regional and National Study

International Journal of Microbiology, 2021
Helicobacter pylori (H. pylori) plays a crucial role in the pathogenesis of gastritis, peptic ulcer, and gastric cancer. The presence of pathogenicity islands (PAI) genes contributes to the pathogenesis of many gastrointestinal disorders.
Rania M. Kishk, Nashaat M. Soliman, Maha M. Anani, Nader Nemr, Ayman Salem, Fawzy Attia, Amal Nooredeen Ahmed Allithy, Marwa Fouad   +7 more
doaj   +1 more source

CagA and VacA Helicobacter Pylori Antibodies in Gastric Cancer

Canadian Journal of Gastroenterology, 2008
BACKGROUND: Infection with different genotypes of virulent Helicobacter pylori strains (cytotoxin-associated gene A [CagA]-and/or vacuolating cytotoxin A [VacA]-positive) can play a role in the development of atrophic gastritis, duodenal ulcer (DU) and ...
Renzo Suriani, Maurilio Colozza, Enrico Cardesi, Dario Mazzucco, Maria Marino, Silvia Grosso, Sabina Sanseverinati, Ivo Venturini, Athos Borghi, Maria Luisa Zeneroli   +9 more
doaj   +1 more source