Results 21 to 30 of about 21,236 (243)

Helicobacter pylori cytotoxin-associated gene A virulence and its association with the epithelial-mesenchymal transition in gastric cancer

Journal of Education, Health and Sport, 2022
Gastric cancer is currently one of the most prevalent malignancies worldwide with a high mortality rate. Helicobacter pylori (H. pylori) infection significantly contributes to the onset and progression of gastric cancer mainly due to the induction of ...
Iga Dudek, Alicja Forma, Justyna Hamerska, Michał Flieger, Jacek Januszewski, Tomasz Cywka, Joanna Kozak, Jacek Baj   +7 more
doaj   +1 more source

The Interrelationship between Cytotoxin-Associated Gene A, Vacuolating Cytotoxin, and Helicobacter pylori-Related Diseases [PDF]

Journal of Infectious Diseases, 1996
The interrelationship between cytotoxin-associated gene A (CagA), vacuolating cytotoxin (VacA), and Helicobacter pylori-related diseases was investigated in 155 H. pylori-infected patients. Four (7%) of 60 subjects had mixed cagA+ and cagA- H. pylori infections. The H. pylori isolates from 98.3% of 121 patients with anti-CagA antibodies were cagA+. The
Weel, J. F., van der Hulst, R. W., Gerrits, Y., Roorda, P., Feller, M., Dankert, J., Tytgat, G. N., van der Ende, A.   +7 more
openaire   +2 more sources

Helicobacter pylori infection is associated with elevated galactose-deficient IgA1 in IgA nephropathy

Renal Failure, 2020
Background Mucosal immunity plays an important role in the pathogenesis of IgA nephropathy (IgAN). This study aimed to investigate if infection of Helicobacter pylori (H.
Xing-Zi Liu, Yue-Miao Zhang, Ni-Ya Jia, Hong Zhang   +3 more
doaj   +1 more source

Frequency of Helicobacter pylori and cytotoxine associated gene A antibodies in patients with cardiac syndrome X [PDF]

Journal of Cardiovascular Disease Research, 2012
Cardiac syndrome X (CSX) is a condition in which patients have the pain of angina despite normal coronary angiogram. Recently, Helicobacter pylori (H. pylori) bacteria has been associated with CSX. However, there is no obvious data about the frequency of its virulent strain (cytotoxine associated gene A: CagA) in patients with CSX.
Rasmi, Yousef, Seyyed-Mohammadzad, Mir-Hossein   +1 more
openaire   +2 more sources

Helicobacter pylori Cytotoxin-Associated Gene A (cagA) and Vacuolating Cytotoxin Gene A (vacA) Genotypes in Gastrointestinal Patients From Central Thailand. [PDF]

Cureus
Introduction The development of diseases associated with Helicobacter pylori (H. pylori) infection is closely linked to its virulence genes, which vary by geographic region. This study aimed to determine the prevalence of H. pylori cytotoxin-associated gene A (cagA) and vacuolating cytotoxin gene A (vacA) genes and their genotypes in patients with ...
Sukthaworn S, Moungthard H, Sirisai C, Anuponganan W, Peerathippayamongkol C, Mus-U-Dee M, Taengchaiyaphum S.   +6 more
europepmc   +3 more sources

Polymorphism in autophagy-related genes LRP1 and CAPZA1 may promote gastric mucosal atrophy

Genes and Environment, 2023
Background Helicobacter pylori secretes cytotoxin-associated gene A (CagA) into the gastric epithelium, causing gastric mucosal atrophy (GMA) and gastric cancer. In contrast, host cells degrade CagA via autophagy.
Naoyuki Yamaguchi, Takuki Sakaguchi, Hajime Isomoto, Tatsuo Inamine, Ryoya Tsukamoto, Daisuke Fukuda, Ken Ohnita, Tsutomu Kanda, Kayoko Matsushima, Tatsuro Hirayama, Kazuo Yashima, Kazuhiro Tsukamoto   +11 more
doaj   +1 more source

The effect of CagA status on response to Helicobacter pylori eradication therapy in Western Turkey

Brazilian Journal of Medical and Biological Research, 2001
If cytotoxin-associated gene A (CagA) status affects the response rates of therapy, then it may be possible to predict Helicobacter pylori eradication rates. We aimed to evaluate the response to eradication treatment of H.
M. Saruç, G. Goksel, S. Ozkaya, F. Guclu, B. Ozbakkaloglu, H. Yuceyar   +5 more
doaj   +1 more source

Helicobacter Pylori Cytotoxin-Associated Gene A (CagA) and Gastric Carcinoma [PDF]

Suez Canal University Medical Journal, 2019
Gastric cancer is a highly lethal disease. Establishment of H. pylori infection as a risk factor for this malignancy help identifying persons at increased risk. Studying the association between the genotypes of H pylori virulence factors and gastric carcinoma would have clinical implications in selecting patients who would benefit from H.
openaire   +1 more source

Differential Expression of α-Enolase in Clinical Gastric Tissues and Cultured Normal/Cancer Cells in Response to Helicobacter pylori Infection and cagA Transfection

Medicina, 2022
Background and Objectives: The role of α-enolase (ENO1) in Helicobacter pylori-related gastric lesions might be a critical factor in the pathogenesis, but remains undefined.
Feiyan Yu, Mengya He, Jian Li, Haiyan Wang, Shuaiyin Chen, Xiaojuan Zhang, Huijuan Zhang, Guangcai Duan, Rongguang Zhang   +8 more
doaj   +1 more source

Helicobacter pylori Infection Maybe a Risk Factor for Cardiac Syndrome X

Frontiers in Cardiovascular Medicine, 2022
PurposeCardiac syndrome X (CSX) is a condition with normal coronary angiography but angina pectoris. Chronic inflammation caused by Helicobacter pylori (H. pylori) infection may play a pathogenic role in CSX.
Dong-Hong Zhang, Chen Yuan, Bei-Bei Wang, Xin-Jiang Dong, Shu-Ping Lv, Fei-Hong Li, Zhen-Xiu Hou, Xiao-Li Liu, Kang Chen   +8 more
doaj   +1 more source