Results 71 to 80 of about 33,889 (177)

Clinical significance of serum Helicobacter pylori antibody cytotoxin-associated gene A levels in patients with unstable angina

European Journal of Medical Research
Objectives We investigated the clinical significance of serum Helicobacter pylori cytotoxin-associated gene A (CagA) antibody levels in 768 patients with unstable angina (UA). Methods Serum CagA levels were measured using ELISA.
Haizhen Jia, Huajun Fan, Jinhe Zhao, Jun Peng, Yunhong Pan, Hongyan Peng   +5 more
doaj   +1 more source

Complement activation lectin pathway (mannose-binding lectin and ficolin) genes polymorphism as the risk factor of CagA positive chronic Helicobacter pylori infection in adolescents

Инфекция и иммунитет, 2020
Currently, features of the host immune response against Helicobacter pylori (Hp) both regarding establishment of chronic carriage after primary infection as well as a role of impaired immune and inflammatory response in the mechanisms of developing ...
Sergey Yu. Tereshchenko, Marina V. Smolnikova, S. N. Zobova   +2 more
doaj  

Early‐Life Nutritional Supplements, Household Environments, and Air Pollution Associated With Children's Helicobacter pylori Infection: A Chinese Multicenter Mother‐Child Study

Safety Science and Technology, Volume 1, Issue 2, June 2026.
Early‐life intake of nutritional additives, particularly during pregnancy and the early postnatal period, reduces the risk of Helicobacter pylori infection (HPI) in children by enhancing immune function and preventing gastrointestinal infections through proper nutrition, supporting the “(Pre‐)Fetal origins of HPI” hypothesis through the “gut–uterine ...
Chan Lu, Yufang Shan, Yuanqi Li, Wen Deng, Yuqing Chen, Yao Chen   +5 more
wiley   +1 more source

A specific A/T polymorphism in Western tyrosine phosphorylation B-motifs regulates Helicobacter pylori CagA epithelial cell interactions.

PLoS Pathogens, 2015
Helicobacter pylori persistently colonizes the human stomach, with mixed roles in human health. The CagA protein, a key host-interaction factor, is translocated by a type IV secretion system into host epithelial cells, where its EPIYA tyrosine ...
Xue-Song Zhang, Nicole Tegtmeyer, Leah Traube, Shawn Jindal, Guillermo Perez-Perez, Heinrich Sticht, Steffen Backert, Martin J Blaser   +7 more
doaj   +1 more source

Malassezia restricta‐Derived Extracellular Vesicles Drive Ovarian Cancer Progression Through JAK2/STAT3‐Mediated M2 Macrophage Polarisation

Microbial Biotechnology, Volume 19, Issue 6, June 2026.
Schematic diagram of the potential mechanism by which Malassezia restricta promote ovarian cancer progression. Malassezia restricta‐derived extracellular vesicles promoted epithelial ovarian cancer progression by inducing M2 macrophage polarisation via activation of the JAK2/STAT3 signalling pathway.
Ying Jiang, Fen Wei, Qingling Yang, Xue Wu, Qifa Huang, Ang Dai, Qi Chen, Tingtao Chen   +7 more
wiley   +1 more source

Helicobacter pylori cagA and vacA genes in dyspeptic Ghanaian patients

BMC Research Notes, 2017
Background Helicobacter pylori infection is prevalent in Ghana. The development of gastro-duodenal disease is dependent on virulence of the infecting strain, host susceptibility and environmental factors.
Timothy N. Archampong, Richard H. Asmah, Ebenezer K. Aidoo, Edwin K. Wiredu, Richard K. Gyasi, David N. Adjei, Sandra Beleza, Christopher D. Bayliss, Karen Krogfelt   +8 more
doaj   +1 more source

Helicobacter pylori CagA and IL-1β Promote the Epithelial-to-Mesenchymal Transition in a Nontransformed Epithelial Cell Model

Gastroenterology Research and Practice, 2016
Gastric cancer is the third cause of cancer death worldwide and infection by Helicobacter pylori (H. pylori) is considered the most important risk factor, mainly by the activity of its virulence factor CagA. H.
Haruki Arévalo-Romero, Isaura Meza, Gabriela Vallejo-Flores, Ezequiel M. Fuentes-Pananá   +3 more
doaj   +1 more source

Relationship of CagA/VacA genotypes of Helicobacter pylori with precursor lesions of gastric cancer

Revista Cubana de Medicina Militar, 2021
Introduction: Helicobacter pylori predisposes to gastric cancer. Individuals with CagA and VacA s1m1 strains develop more severe mucosal lesions. The Operative Link on Gastritis Assessment system allows determining the risk of cancer and defines atrophy ...
Ludmila Martínez Leyva, Teresita de Jesús Montero González, Felipe Neri Piñol Jiménez, Amada Palomino Besada, Osvaldo Miranda Gómez, Danay Días Morejón   +5 more
doaj  

Gastroduodenal pathology in the light of Helicobacter pylori genotype in Egyptian patients

The Egyptian Journal of Internal Medicine, 2019
Context Infection with Helicobacter pylori is associated with gastroduodenal diseases such as gastritis, gastric ulcer, duodenal ulcer, gastric cancer, and mucosa-associated lymphoid tissue lymphoma.
Eman Azzam, Ezzat Ali, Shwikar Ahmed, Ahmed Talha   +3 more
doaj   +1 more source

Interactions between CagA and smoking in gastric cancer

World Journal of Gastroenterology, 2011
To examine the interactions between cytotoxin-associated gene (CagA) positive Helicobacter pylori infection and smoking in non-cardiac gastric cancer.A case-control study (257 cases and 514 frequency-matched controls) was conducted from September 2008 to July 2010 in Xi'an, China. Cases were newly diagnosed, histologically confirmed non-cardiac cancer.
Xiao-Qin, Wang, Hong, Yan, Paul D, Terry, Jian-Sheng, Wang, Li, Cheng, Wen-An, Wu, Sen-Ke, Hu   +6 more
openaire   +2 more sources