Results 191 to 200 of about 4,390,669 (264)

Understanding the tradeoffs between quality and morality: Insights from consumer response to animal welfare eggs in China. [PDF]

Poult Sci
Zhang J, Liu Y, Wang J, Tan X.
europepmc   +1 more source

Astrocytic Ketogenesis Protects Central Nervous System Injury via CPT1A Stabilization and Epigenetic Regulation

Advanced Science, EarlyView.
A distinct astrocyte subpopulation, enriched at the lesion border, drives CNS repair through enhanced ketone body metabolism. This process promotes neuronal survival and axonal sparing via CPT1A stabilization and H3K9bhb‐dependent epigenetic reprogramming, positioning astrocytic ketogenesis as a promising therapeutic target for tissue regeneration ...
Dishui Pan, Haoming Shu, Rui Gao, Yilong Ren, Wu Ye, Xuhui Ge, Yao Gu, Yufeng Zhu, Xiaokun Wang, Honglin Teng, Xuhui Zhou, Wei Liu, Yang Gao, Jianquan Zhao, Weihua Cai   +14 more
wiley   +1 more source

The effects of adolescent social isolation and group housing on adolescent binge drinking in mice. [PDF]

PLoS One
Lodha J, Morgan A, Balguri R, Purcell V, Wolstenholme JT.   +4 more
europepmc   +1 more source

A Programmable Braided Silk‐Glass Fiber Ligament Promoting Rapid Motoric Recovery

Advanced Science, EarlyView.
A scalable three‐dimensional braiding strategy integrates silk and glass fibers into customizable artificial ligaments with programmable “J‐shaped” nonlinear mechanics. The silk‐rich architecture supports osseoligamentous integration, while glass fibers provide mechanical reinforcement and biomimetic mineralization cues, enabling strain‐adaptive load ...
Changbo Lu, Daming Liu, Haoxin Zhang, Zhiwei Qiao, Qiuming Gao, Jia Meng, Hongyin Yue, Songkai Li, Shuo Zhang, Tao Yuan, Yun Xue, Hui Jiang, Zhenguo Liu, Yibo Wang, Nirong Bao, Yuli Chen, Xiaojiang Yang   +16 more
wiley   +1 more source

Implementing cage-free egg commitments in China: An explorative qualitative interview study of corporate and certification perspectives on cage-free egg procurement. [PDF]

Anim Welf
Yang Q, Dwyer CM, Langford FM, Zhao R, Vigors B.   +4 more
europepmc   +1 more source

Fuyuan Huoxue Decoction Promotes Lumbar Interbody Fusion in Rats: Role of Macrophage‐Driven Inflammation and the TLR9/NF‐κB Pathway

Advanced Science, EarlyView.
Fuyuan Huoxue decoction improves lumbar interbody fusion in rats while reducing inflammatory macrophage activity and supporting bone‐forming stem cells. Experiments implicate extracellular DNA and TLR9/NF‐κB signaling in early responses. These findings point to coordinated control of inflammation and osteogenesis as a potential route to stronger spinal
Hongwei Gao, Han Wu, Shaorong Li, Weijian Wang, Yijian Guo, Shuai Cheng, Jiayi Sun, Jilong An, Wei Zhang   +8 more
wiley   +1 more source

Airflow constraints govern natural airborne transmission of tuberculosis. [PDF]

mSphere
Naqvi KF, Guo Y, Kulkarni Y, Sapkota D, Lu P, Wang S, Dias BRS, Ektnitphong VA, Martin AE, Evers BM, Lu LL, Ouyang H, Bourouiba L, Shiloh MU.   +13 more
europepmc   +1 more source

Lactate Drives Pathological Browning of White Adipose Tissue to Aggravate Sepsis‐Associated Metabolic Disorders in a GPR81‐Dependent Manner

Advanced Science, EarlyView.
Sepsis‐triggered lactate accumulation induces pathological white adipose tissue browning. Lactate activates adipocyte GPR81 to sequentially upregulate CTRP6‐p38 signalling and UCP1 expression. This cascade exacerbates sepsis‐associated metabolic disorders.
Chunliang Zheng, Xiaohua Li, Shuo Li, Chungen Xing, Chun Cao   +4 more
wiley   +1 more source

Non‐Canonical Function of DDX21 in Fetal Hematopoiesis Antagonizes KDM5A‐Mediated Repression of Ribosomal and Hematopoietic Genes

Advanced Science, EarlyView.
This study demonstrates a mechanism by which RNA helicase DDX21 coordinates the transcription of hematopoietic and ribosomal genes by interacting with the H3K4me3 demethylase KDM5A. The DDX21‐KDM5A complex co‐occupies active genes in hematopoietic progenitors, thereby ensuring their rapid proliferation during fetal hematopoiesis.
Adrian On‐Wah Leung, Chang Li, Xianyin Huang, Zhuming Fan, Yuning Chen, Jiaxing Liu, Hong Man Lin, Xiaoming Cui, Fujia Zhang, Ruoxi Niu, Kam Tong Leung, Boxian Huang, Hoi‐Hung Cheung   +12 more
wiley   +1 more source

Environment shapes gut microbiome and determines susceptibility to DSS-colitis in <i>Adamdec1^-/-</i> mice. [PDF]

Front Immunol
Kumagai T, Rath S, Fan S, Rahman FZ, Smith AM.   +4 more
europepmc   +1 more source