Results 71 to 80 of about 3,904 (202)

Serum 25‐hydroxyvitamin D, vitamin D receptor, and vitamin D binding protein concentrations in dogs with acute pancreatitis compared to healthy control dogs

Journal of Veterinary Internal Medicine, 2023
Background Previous studies have documented vitamin D imbalance in dogs with acute pancreatitis (AP), but no studies have investigated serum vitamin D receptor (VDR) and vitamin D‐binding protein (VDBP) concentrations.
Dohee Lee, Yoonhoi Koo, Yeon Chae, Yeongeun Choi, Taesik Yun, Byeong‐Teck Kang, Mhan‐Pyo Yang, Hakhyun Kim   +7 more
doaj   +1 more source

Vitamin D supplementation is effective for olanzapine-induced dyslipidemia

Frontiers in Pharmacology, 2023
Olanzapine is an atypical antipsychotic drug that is clinically applied in patients with schizophrenia. It increases the risk of dyslipidemia, a disturbance of lipid metabolic homeostasis, usually characterized by increased low-density lipoprotein (LDL ...
Zijian Zhou, Takuya Nagashima, Takuya Nagashima, Chihiro Toda, Mone Kobayashi, Takahide Suzuki, Kazuki Nagayasu, Hisashi Shirakawa, Satoshi Asai, Shuji Kaneko   +9 more
doaj   +1 more source

Adjunctive Active Vitamin D Decreases Kidney Function during Treatment of Secondary Hyperparathyroidism with Extended-Release Calcifediol in Non-Dialysis Chronic Kidney Disease in a Randomized Trial.

Am J Nephrol
Introduction: Sustained 30% reductions of intact parathyroid hormone (iPTH) with extended-release calcifediol (ERC) are associated with slower decline in estimated glomerular filtration rate (eGFR) in non-dialysis chronic kidney disease (ND-CKD) patients
Ashfaq A, Choe J, Strugnell SA, Patel N, Sprague SM, Norris KC, Lerma E, Petkovich PM, Bishop CW, Ashfaq A.   +9 more
europepmc   +2 more sources

Synergistic Tuning of Conformational Dynamics, Electron Tunneling, and Substrate Positioning Enhances Electron Transfer in a P450 Chimera for Calcifediol Biosynthesis (Adv. Sci. 22/2026)

Advanced Science, Volume 13, Issue 22, 17 April 2026.
Electron Transfer Optimization Strategy Enables Efficient P450‐Mediated Calcifediol Synthesis This cover illustrates a holistic optimization strategy integrating conformational modulation, electron transfer (ET) pathway engineering, and substrate positioning, applied to enhance the ET efficiency of chimeric P450 L21 for calcifediol synthesis.
Ziqi Liang, Xitong Song, Shuming Cheng, Yiwen Shen, Jie Zhang, Yaru Wang, Huiying Luo, Bin Yao, Binju Wang, Tao Tu   +9 more
wiley   +1 more source

Effect of calcifediol supplementation on renin‐angiotensin‐aldosterone system mediators in dogs with chronic kidney disease

Journal of Veterinary Internal Medicine, 2022
Background Chronic kidney disease (CKD) leads to low serum concentrations of vitamin D metabolites. Thus, hypovitaminosis D associated with CKD might contribute to disease progression via increased concentration of renin angiotensin aldosterone system ...
Matthew Miller, Jessica Quimby, Catherine Langston, Marisa Ames, Valerie J. Parker   +4 more
doaj   +1 more source

Asthma and vitamin D in Brazilian adolescents: Study of Cardiovascular Risks in Adolescents (ERICA)

Jornal Brasileiro de Pneumologia, 2021
Objective: To evaluate the association between asthma prevalence and serum levels of vitamin D in Brazilian adolescents. Methods: This was a cross-sectional, school-based study involving adolescents between 12-17 years of age from four large Brazilian ...
Cláudia Soïdo Falcão do Amaral, Érica Azevedo de Oliveira Costa Jordão, Cecília Lacroix de Oliveira, Mara Morelo Rocha Felix, Maria Cristina Caetano Kuschnir, Fábio Chigres Kuschnir   +5 more
doaj   +2 more sources

Steroid Recognition in Adhesion GPCRs: A Structural and Pharmacological Perspective

Pharmacology Research &Perspectives, Volume 14, Issue 2, April 2026.
ABSTRACT Emerging evidence suggests steroids may act as generalizable ligands for adhesion GPCRs, a receptor class with considerable pharmacological potential. While most studies have focused on the ADGR‘G' subfamily, recent cryo‐EM structures of the androgens 5α‐dihydrotestosterone (5α‐DHT) and methenolone bound to ADGRD1 revealed a putative steroid ...
Bethany Fleming, Abdul‐Akim Guseinov, Irina G. Tikhonova, Graeme Milligan, Nicole A. Perry‐Hauser   +4 more
wiley   +1 more source

Optimizing Muscle Health in Sarcopenia With Dietary Supplements: A Narrative Review

JCSM Communications, Volume 9, Issue 1, January/June 2026.
ABSTRACT Aims Sarcopenia, the age‐related decline in skeletal muscle mass, strength and functionality, significantly contributes to frailty, falls and disability among older adults, resulting in increased morbidity, mortality and healthcare expenditures.
McKenna W. Box, Troy B. Puga, Nathan R. McKenzie, Joseph J. Ruff, Humza Razaq, Lachlan F. Anderson, John T. Riehl   +6 more
wiley   +1 more source

Evaluation of Therapies for Secondary Hyperparathyroidism Associated with Vitamin D Insufficiency in Chronic Kidney Disease

Kidney Diseases, 2023
Introduction: Parathyroid hormone-lowering responses after administration of three different therapies capable of raising serum total 25-hydroxyvitamin D (25OHD) were evaluated in patients with secondary hyperparathyroidism (SHPT), vitamin D ...
Stephen A. Strugnell, Philipp Csomor, Akhtar Ashfaq, Charles W. Bishop   +3 more
doaj   +1 more source

Intersections of vitamin D deficiency, HIV and chronic liver diseases

HIV Medicine, Volume 27, Issue 1, Page 4-17, January 2026.
Abstract Objectives Despite effective antiretroviral therapy (ART), chronic liver diseases remain a leading cause of morbidity and mortality among people with HIV, with metabolic dysfunction–associated steatotic liver disease (MASLD) now the predominant etiology. Vitamin D deficiency is also highly prevalent in this population.
Francesca Farina, Aurgho Datta, Suzanne N. Morin, Sahar Saeed, Bertrand Lebouche, Giovanni Guaraldi, Salvatore Petta, Giada Sebastiani   +7 more
wiley   +1 more source