Results 71 to 80 of about 4,051 (202)
Background Vitamin D has shown to play a role in multiple diseases due to its skeletal and extraskeletal actions (such as immunomodulation). In this sense, vitamin D deficiency has become a worldwide health issue.
Chinchilla Gallo, Sandra Pamela +5 more
core +1 more source
Context Secondary hyperparathyroidism (SHPT) is a complication of chronic kidney disease (CKD) affecting mineral and bone metabolism and characterized by excessive parathyroid hormone (PTH) production and parathyroid hyperplasia.
M. Franchi +5 more
semanticscholar +1 more source
Steroid Recognition in Adhesion GPCRs: A Structural and Pharmacological Perspective
ABSTRACT Emerging evidence suggests steroids may act as generalizable ligands for adhesion GPCRs, a receptor class with considerable pharmacological potential. While most studies have focused on the ADGR‘G' subfamily, recent cryo‐EM structures of the androgens 5α‐dihydrotestosterone (5α‐DHT) and methenolone bound to ADGRD1 revealed a putative steroid ...
Bethany Fleming +4 more
wiley +1 more source
Optimizing Muscle Health in Sarcopenia With Dietary Supplements: A Narrative Review
ABSTRACT Aims Sarcopenia, the age‐related decline in skeletal muscle mass, strength and functionality, significantly contributes to frailty, falls and disability among older adults, resulting in increased morbidity, mortality and healthcare expenditures.
McKenna W. Box +6 more
wiley +1 more source
Physiological Basis for Using Vitamin D to Improve Health
Vitamin D is essential for life—its sufficiency improves metabolism, hormonal release, immune functions, and maintaining health. Vitamin D deficiency increases the vulnerability and severity of type 2 diabetes, metabolic syndrome, cancer, obesity, and ...
Sunil J. Wimalawansa
doaj +1 more source
Intersections of vitamin D deficiency, HIV and chronic liver diseases
Abstract Objectives Despite effective antiretroviral therapy (ART), chronic liver diseases remain a leading cause of morbidity and mortality among people with HIV, with metabolic dysfunction–associated steatotic liver disease (MASLD) now the predominant etiology. Vitamin D deficiency is also highly prevalent in this population.
Francesca Farina +7 more
wiley +1 more source
BackgroundObesity (OB) is a chronic metabolic disease with important associated comorbidities and mortality. Vitamin D supplementation is frequently administered after bariatric surgery (BS), so as to reduce OB-related complications, maybe including ...
Aura D. Herrera-Martínez +32 more
doaj +1 more source
Disclosure: H.C. Chan: None. S. Bhoora: None. E. Zhou: None. S. Marais: None. T. Pillay: None. R. Punchoo: None. The Vitamin D metabolome shows anti-neoplastic activity in many pre-clinical studies.
Hoi Ching Cherry Chan +5 more
semanticscholar +1 more source
The Concise Guide to PHARMACOLOGY 2025/26: Enzymes
The Concise Guide to Pharmacology 2025/26 marks the seventh edition in this series of biennial publications in the British Journal of Pharmacology. Presented in landscape format, the guide provides a comparative overview of the pharmacology of drug target families. The concise nature of the Concise Guide refers to the style of presentation, being clear,
Stephen P. H. Alexander +31 more
wiley +1 more source
ABSTRACT Bariatric surgery is the most clinically‐ and cost‐effective intervention for severe obesity. However, without adequate follow‐up, it can lead to nutritional deficiencies. Patients require life‐long nutritional supplements and follow‐up to prevent nutritional deficiencies from developing.
Sophie Haughton +2 more
wiley +1 more source

