Results 71 to 80 of about 19,695 (283)

Eficácia do AlCl3 e etanol na prevenção da calcificação de fragmentos da parede aórtica porcina fixados em GDA Efficacy of AlCl3 and ethanol in the prevention of calcification of fragments of porcine aortic wall fixed in GDA

Brazilian Journal of Cardiovascular Surgery, 2006
OBJETIVO: Avaliar a eficácia do cloreto de alumínio, isoladamente ou em associação com o etanol, na prevenção da calcificação e da resposta inflamatória de fragmentos de parede aórtica porcina fixada em glutaraldeído (GDA), implantados no tecido ...
Evandro Antonio Sardeto, Francisco Diniz Affonso da Costa, Iseu do Santo Elias Affonso da Costa, João Gabriel Roderjan, Eduardo Discher, Ricardo Alexandre Schneider, Carlos Henrique Gori Gomes, Claudinei Colattusso, Daniel Précoma, Andrea Dumsch, Sergio Veiga Lopes, Jairo Leal   +11 more
doaj   +1 more source

Long‐term culture of skin biopsies: maintenance of fibroblast production and competency of reprogramming

FEBS Open Bio, EarlyView.
Skin biopsies taken from a patient with an ultra‐rare disorder as well as controls were cultured for up to 473 days. The chunks of skin were serially transferred to a new culture plate when confluent with fibroblasts. Different generations of fibroblasts were analyzed for cell and molecular properties, proliferation, and competence for reprogramming to
Sudiksha Rathan‐Kumar, Michael A. Ripperger, Grant M. Westlake, Kevin C. Ess   +3 more
wiley   +1 more source

The photoswitchable cannabinoid azo‐HU308 enables optical control of Ca2+ dynamics in INS‐1 β‐cells via off‐target effects on TRPC channels

FEBS Open Bio, EarlyView.
Light activation of the photoswitchable cannabinoid ligand azo‐HU308 triggers Ca2+ influx in pancreatic β‐cells through TRPC channels, independent of CB2 cannabinoid receptors. This reveals a non‐GPCR pathway for cannabinoid modulation of β‐cell Ca2+ dynamics and establishes azo‐HU308 as an optical tool to study cannabinoid signaling through TRP ...
Alexander E. G. Viray, James A. Frank
wiley   +1 more source

Exploring associations between breast tumor inflammatory gene expression and mammographic calcifications and masses in a community-based population

Scientific Reports
Mammography is important for breast cancer detection, and calcifications and masses are the most common mammographic features. In this exploratory study, we evaluated the association between these findings and immune gene expression to determine the role
Nathan C. Shaul, Melissa A. Troester, Alina M. Hamilton, Sheila S. Lee, Louise M. Henderson, Sarah J. Nyante   +5 more
doaj   +1 more source

Naked cuticle is essential for Drosophila wing development beyond Wingless signaling

FEBS Open Bio, EarlyView.
Naked cuticle (Nkd), a Wnt signaling inhibitor, assumes extensive roles in Drosophila wing development. Overexpressing Nkd causes smaller, crumpled wings, while also perturbing multiple signaling pathways and developmental genes. A specific region (R1S) is critical for Nkd's function as a signaling integrator, offering new insights for studying its ...
Rui Wang, Ping Wang
wiley   +1 more source

The effect of salubrinal on the endoplasmic reticulum stress pathway in heat‐stressed spermatogonial cells in vitro

FEBS Open Bio, EarlyView.
This study investigates the protective role of salubrinal against heat‐induced endoplasmic reticulum (ER) stress in mouse spermatogenic cells (GC1 and GC2). By modulating the ER stress pathway, salubrinal alleviates cellular stress and supports spermatogenic cell survival, suggesting its potential as a therapeutic candidate for heat‐related infertility.
Suna Karadeniz Saygili, Mustafa Oztatlici, Mahmut Kemal Ozbilgin   +2 more
wiley   +1 more source

Physiological controls on seawater uptake and calcification in the benthic foraminifer Ammonia tepida [PDF]

Biogeosciences, 2009
Abstract. During the last decades conceptual models describing the calcification pathway of foraminifera and its physiological controls have been developed. These models are derived by combining data of tracer experiments and microscopic observations obtained from different species.
de Nooijer, Lennart Jan, Langer, Gerald, Nehrke, Gernot, Bijma, Jelle   +3 more
openaire   +7 more sources

The living aortic valve: From molecules to function. [PDF]

, 2014
The aortic valve lies in a unique hemodynamic environment, one characterized by a range of stresses (shear stress, bending forces, loading forces and strain) that vary in intensity and direction throughout the cardiac cycle.
Bertazzo, S, Butcher, JT, Chester, AH, El-Hamamsy, I, Latif, N, Yacoub, MH   +5 more
core   +1 more source

Polarization‐resolved femtosecond Vis/IR spectroscopy tailored for resolving weak signals in biological samples using minimal sample volume

FEBS Open Bio, EarlyView.
Unique biological samples, such as site‐specific mutant proteins, are available only in limited quantities. Here, we present a polarization‐resolved transient infrared spectroscopy setup with referencing to improve signal‐to‐noise tailored towards tracing small signals. We provide an overview of characterizing the excitation conditions for polarization‐
Clark Zahn, Karsten Heyne
wiley   +1 more source

Diagnostic reproducibility of the elongated styloid process Reprodutibilidade diagnóstica do alongamento do processo estilóide

Journal of Applied Oral Science, 2003
The aim of this study was to estimate the reproducibility related to the presence and to the measurements of elongated styloid process (ESP), based on panoramic radiographs and the prevalence of ESP.
Gulnara Scaf, Deborah Queiroz de Freitas, Leonor de Castro Monteiro Loffredo   +2 more
doaj   +1 more source