Results 11 to 20 of about 508,286 (387)

HDAC9 is implicated in atherosclerotic aortic calcification and affects vascular smooth muscle cell phenotype. [PDF]

Nature Genetics, 2019
Aortic calcification is an important independent predictor of future cardiovascular events. We performed a genome-wide association meta-analysis to determine SNPs associated with the extent of abdominal aortic calcification (n = 9,417) or descending ...
Bagchi, Aranya, Barnes, Hanna J, Bloch, Donald B, Bowden, Donald W, Budoff, Matthew, Buswell, Mary D, Buys, Emmanuel S, Campbell, Catherine Y, Criqui, Michael H, Debette, Stephanie, Erbel, Raimund, Feitosa, Mary F, Franceschini, Nora, Freedman, Barry I, Gudnason, Vilmundur, Guo, Xiuqing, Harris, Tamara, Hoffmann, Udo, Hwang, Shih-Jen, Johnson, Andrew D, Jöckel, Karl-Heinz, Kälsch, Hagen, Lindsay, Mark E, Lino Cardenas, Christian L, Lu, Lingyi, Malhotra, Rajeev, Mauer, Andreas C, Moebus, Susanne, Nicholson, Christopher J, Nigwekar, Sagar U, Nöthen, Markus M, O'Donnell, Christopher J, Pechlivanis, Sonali, Post, Wendy S, Rhee, David K, Rotter, Jerome I, Rourke, Caitlin O', Shelton, Georgia, Sigurdsson, Sigurdur, Sigurslid, Haakon H, Slocum, Charles, Smith, Albert V, Song, Ci, Thanassoulis, George, Wang, Judy, Wong, Quenna, Wunderer, Florian, Yao, Jie, Zapol, Warren M, Zhang, Xiaoling   +49 more
core   +2 more sources

Endogenous Calcification Inhibitors in the Prevention of Vascular Calcification: A Consensus Statement From the COST Action EuroSoftCalcNet

Frontiers in Cardiovascular Medicine, 2019
The physicochemical deposition of calcium-phosphate in the arterial wall is prevented by calcification inhibitors. Studies in cohorts of patients with rare genetic diseases have shed light on the consequences of loss-of-function mutations for different ...
Magnus Bäck, Tamas Aranyi, M. Leonor Cancela, Miguel Carracedo, Natércia Conceição, Georges Leftheriotis, Vicky Macrae, Ludovic Martin, Yvonne Nitschke, Andreas Pasch, Daniela Quaglino, Frank Rutsch, Catherine Shanahan, Victor Sorribas, Flora Szeri, Flora Szeri, Pedro Valdivielso, Olivier Vanakker, Hervé Kempf   +18 more
doaj   +2 more sources

Aged bone matrix-derived extracellular vesicles as a messenger for calcification paradox

Nature Communications, 2022
Adipocyte differentiation of bone marrow mesenchymal stem/stromal cells (BMSCs) instead of osteoblast formation contributes to age- and menopause-related marrow adiposity and osteoporosis.
Zhenxing Wang, Zhong-Wei Luo, Fu-Xing-Zi Li, Jia Cao, Shan-shan Rao, Yi-Wei Liu, Yiyi Wang, Guoling Zhu, Jiang-Shan Gong, Jing-Tao Zou, Qiang Wang, Yijuan Tan, Yan Zhang, Yin Hu, You‐You Li, Hao Yin, Xiao-Kai Wang, Zehui He, Lu Ren, Zheng-Zhao Liu, Xiong‐Ke Hu, Ling-Qing Yuan, Ran Xu, Chun-Yuan Chen, Hui Xie   +24 more
semanticscholar   +1 more source

Vascular Calcification: Key Roles of Phosphate and Pyrophosphate

International Journal of Molecular Sciences, 2021
Cardiovascular complications due to accelerated arterial stiffening and atherosclerosis are the leading cause of morbimortality in Western society. Both pathologies are frequently associated with vascular calcification.
R. Villa-Bellosta
semanticscholar   +1 more source

Arterial calcifications [PDF]

Journal of Cellular and Molecular Medicine, 2010
Abstract Introduction Arterial calcification in specific patient populations at high risk for cardiovascular disease Summary Arterial calcifications as found with various imaging techniques, like plain X‐ray, computed tomography or ultrasound are associated with increased cardiovascular risk.
Abraham A. Kroon, Coen D.A. Stehouwer, Roger J M W Rennenberg, Leon J. Schurgers   +3 more
openaire   +4 more sources

Aortic Calcification [PDF]

European Journal of Vascular and Endovascular Surgery, 2005
Vascular calcification is a complicating factor observed in advanced atherosclerosis. This review summarises the present knowledge regarding abdominal aortic calcification.Literature review.A literature review was carried using MEDLINE and PUBMED with the search terms 'abdominal', 'aortic' and 'calcification'.
Jayalath, R. W., Mangan, S. H., Golledge, J.   +2 more
openaire   +3 more sources

Vascular Calcification—New Insights into Its Mechanism

International Journal of Molecular Sciences, 2020
Vascular calcification (VC), which is categorized by intimal and medial calcification, depending on the site(s) involved within the vessel, is closely related to cardiovascular disease.
S. Lee, In-kyu Lee, Jae-Han Jeon
semanticscholar   +1 more source

Trimethylamine-N-Oxide Promotes Vascular Calcification Through Activation of NLRP3 (Nucleotide-Binding Domain, Leucine-Rich-Containing Family, Pyrin Domain-Containing-3) Inflammasome and NF-κB (Nuclear Factor κB) Signals

Arteriosclerosis, Thrombosis and Vascular Biology, 2020
Supplemental Digital Content is available in the text. Objectives: Vascular calcification is highly prevalent in patients with chronic kidney disease. Increased plasma trimethylamine N-oxide (TMAO), a gut microbiota-dependent product, concentrations are ...
Xiuli Zhang, Yining Li, Pingzhen Yang, Xiaoyu Liu, Lihe Lu, Yantin Chen, Xinglong Zhong, Zehua Li, Hailin Liu, Caiwen Ou, Jianyun Yan, Minsheng Chen   +11 more
semanticscholar   +1 more source

Calcification in Atherosclerotic Plaque Vulnerability: Friend or Foe?

Frontiers in Physiology, 2020
Calcification is a clinical marker of atherosclerosis. This review focuses on recent findings on the association between calcification and plaque vulnerability.
Xuan-YAN Shi, Jie Gao, Qiushi Lv, Haodi Cai, F. Wang, Ruidong Ye, Xinfeng Liu   +6 more
semanticscholar   +1 more source

Coronary-artery calcification in young adults with end-stage renal disease who are undergoing dialysis.

New England Journal of Medicine, 2000
BACKGROUND Cardiovascular disease is common in older adults with end-stage renal disease who are undergoing regular dialysis, but little is known about the prevalence and extent of cardiovascular disease in children and young adults with end-stage renal ...
W. Goodman, J. Goldin, B. Kuizon, Chun Yoon, B. Gales, Donna M. Sider, Yan Wang, Joanie Chung, Aletha M Emerick, L. Greaser, R. Elashoff, I. Salusky   +11 more
semanticscholar   +1 more source