Results 121 to 130 of about 2,749 (172)

S100a4 secreted by alternatively activated alveolar macrophages promotes activation of lung fibroblasts in pulmonary fibrosis [PDF]

, 2016
Zhang, Wei
core  

Correction for Metaferia et al., Phenotypic screening of the ReFRAME drug repurposing library to discover new drugs for treating sickle cell disease. [PDF]

Proc Natl Acad Sci U S A
europepmc   +1 more source

Rac1 Temporarily Suppresses Fertilization Envelope Formation Immediately After 1-Methyladenine Stimulation. [PDF]

Cells
Aida S, Matsumoto T, Yamazaki Y, Limatola N, Santella L, Chiba K.   +5 more
europepmc   +1 more source

High throughput screening assay for the identification of ATF4 and TFEB activating compounds. [PDF]

Autophagy Rep
Pfau DJ, Bryk R.
europepmc   +1 more source

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A total synthesis of polyether antibiotic (−)-A23187 (calcimycin)

Tetrahedron Letters, 1987
Abstract A total synthesis of (−)-A23187 (calcimycin) was accomplished by a convergent approach. The key step of synthesis was the stereospecific cyclization of the β-hydroxy ketone into the spiroketal under basic conditions.
Yoshito Kishi
exaly   +2 more sources

Stereocontrolled total synthesis of Antibiotic A-23187 (calcimycin)

Journal of the American Chemical Society, 1982
Der ausgehend vom Keton (I) zugangliche Alkohol (Va) wird durch Oxidation und Grignardreaktion zu einem trennbaren Gemisch der Vinylderivate (Vb) + (Vc) umgesetzt, die sich beide in mehreren Stufen in den Ester (VIa) bzw. dessen Folgeprodukt (VIb) uberfuh; ren lassen.
Gregory R. Martinez, Paul A. Grieco, Eric Williams, Kenichi Kanai, C. V. Srinivasan   +4 more
exaly   +2 more sources

Semi-synthesis of A23187 (calcimycin) analogs

Experientia, 1983
The cleavage of A23187 to give a synthon (4) and the semi-synthesis from (4) of 2 Des-N-methylamino A23187 isomers (7a,b) are described. The antibiotic activities of the acids analogous to A23187(1), (2), (7a), (7b) are compared.
M. Prudhomme, G. Jeminet
exaly   +2 more sources

Calcimycin potentiates responses of rat hippocampal neurons to N-methyl-d-aspartate

Brain Research, 1991
We examined the effect of elevating intracellular calcium ([Ca2+]i) on responses to iontophoretically applied N-methyl-D-aspartate (NMDA), and quisqualate in CA1 neurons of the hippocampal slice. Topical application of calcimycin (A23187), a calcium ionophore, potentiated responses to NMDA but not to quisqualate.
H, Markram, M, Segal
exaly   +3 more sources

Mutasynthesis of pyrrole spiroketal compound using calcimycin 3-hydroxy anthranilic acid biosynthetic mutant

Applied Microbiology and Biotechnology, 2013
The five-membered aromatic nitrogen heterocyclic pyrrole ring is a building block for a wide variety of natural products. Aiming at generating new pyrrole-containing derivatives as well as to identify new candidates that may be of value in designing new anticancer, antiviral, and/or antimicrobial agents, we employed a strategy on pyrrole-containing ...
Jingdan Liang, Zhijun Wang
exaly   +3 more sources