Bile acids activate ryanodine receptors in pancreatic acinar cells via a direct allosteric mechanism [PDF]
, 2015 The earliest critical event of pancreatitis is a long lasting high amplitude rise of intracellular Ca(2+) concentration of the acinar cell, which can be triggered by high concentration of bile acids.
Almássy, János +4 more
core +1 more source
N-cinnamoylanthranilates as human TRPA1 modulators: Structure-activity relationships and channel binding sites [PDF]
, 2019 The transient receptor potential ankyrin 1 (TRPA1) channel is a non-selective cation channel, which detects noxious stimuli leading to pain, itch and cough. However, the mechanism(s) of channel modulation by many of the known, non-reactive modulators has
Boa, AN +4 more
core +2 more sources
Interventions to improve antibiotic prescribing practices for hospital inpatients [PDF]
, 2017 Background Antibiotic resistance is a major public health problem. Infections caused by multidrug-resistant bacteria are associated with prolonged hospital stay and death compared with infections caused by susceptible bacteria. Appropriate antibiotic use
Brown, Erwin +8 more
core +3 more sources
System for measurement of concentration of intracellular calcium in LabVIEW [PDF]
, 2014 Diplomová práce se zabývá osvojením metod pro měření koncentrace intracelulárního vápníku, a takže odpovídajícím zařízením v prostředí LabVIEW. Práce se skládá ze dvou částí.
Kormanovskaya, Elena
core
Characteristics of the Sarcoplasmic Reticulum Ca 2+ -dependent ATPase from Masticatory Muscles [PDF]
, 2004 We compared the sarcoplasmic reticulum (SR) Ca-ATPase from masseter (M) and medial pterygoid (MP) muscles with that from fast muscles (FM) to examine whether its calcium transport capability and enzymatic activity are different.
Alonso, Guillermo Luis +3 more
core +1 more source
Effect of PMA on Autophagy in Human Monocyte Cell-Line, THP-1 [PDF]
, 2015 THP-1 cells are human monocyte like cell line that is blocked at certain steps of the differentiation process and its differentiation into macrophages can be induced by addition of PMA.
Behura, Assirbad
core
DIANNEXIN DOWN-MODULATES TNF-INDUCED ENDOTHELIAL MICROPARTICLE RELEASE BY BLOCKING MEMBRANE BUDDING PROCESS. [PDF]
, 2016 BACKGROUND: Microparticles are now recognised as true biological effectors with a role in immunopathology through their ability to disseminate functional properties. Diannexin, a homodimer of annexin V, binds to PS with a higher affinity and longer blood
Allison, AC +4 more
core +1 more source
Discrimination of Dormant and Active Hematopoietic Stem Cells by G0 Marker Reveals Dormancy Regulation by Cytoplasmic Calcium [PDF]
, 2019 Quiescent hematopoietic stem cells (HSCs) are typically dormant, and only a few quiescent HSCs are active. The relationship between “dormant” and “active” HSCs remains unresolved.
Asada, Shuhei +19 more
core +1 more source
Surfactant Assemblies and their Various Possible Roles for the Origin(S) of Life [PDF]
, 2018 A large number of surfactants (surface active molecules) are chemically simple compounds that can be obtained by simple chemical reactions, in some cases even under presumably prebiotic conditions.
Walde, Peter
core
Live birth following an innovative artificial oocyte activation protocol using double calcium stimulators. [PDF]
Chin Med J (Engl), 2023 Gao Y, Yang D, Fang Y, Wang X, Li D.
europepmc +1 more source