Results 41 to 50 of about 2,232 (157)

Monocyte‐derived extracellular vesicles, stimulated by Trypanosoma cruzi, enhance cellular invasion in vitro via activated TGF‐β1

Journal of Extracellular Vesicles, Volume 13, Issue 11, November 2024.
Abstract During cell invasion, large Extracellular Vesicle (lEV) release from host cells was dose‐dependently triggered by Trypanosoma cruzi metacyclic trypomastigotes (Mtr). This lEV release was inhibited when IP3‐mediated Ca2+ exit from the ER and further Ca2+ entry from plasma membrane channels was blocked, but whilst any store‐independent Ca2 ...
Ephraim A. Ansa‐Addo, Paras Pathak, Maria V. McCrossan, Izadora Volpato Rossi, Mahamed Abdullahi, Dan Stratton, Sigrun Lange, Marcel I. Ramirez, Jameel M. Inal   +8 more
wiley   +1 more source

Calcium additional to that bound to the transport sites is required for full activation of the sarcoplasmic reticulum Ca-ATPase from skeletal muscle [PDF]

, 1998
The sarcoplasmic reticulum Ca-ATPase is fully activated when ≃1 μM [Ca2+] saturates the two transport sites; higher [Ca] inhibits the ATPase by competition of Ca-ATP with Mg-ATP as substrates.
Takara, Delia, González, Débora A., Ostuni, Mariano A., Sánchez, Gabriel A., Alonso, Guillermo L.   +4 more
core   +1 more source

Mitochondrial plasticity and synaptic plasticity crosstalk; in health and Alzheimer's disease

CNS Neuroscience &Therapeutics, Volume 30, Issue 8, August 2024.
The mechanism of mitochondrial transport within the neuron is mediated on the cytoskeleton. The retrograde (−) motion deployed the movement of mitochondria toward the cell body with the help of dynein, TRAK1/2, and Mrio1/2 protein. While anterograde (+) motion causes the movement toward the axon with the assistance of kinesin, TRAK1/2, and Miro1/2 ...
Fatemeh Sayehmiri, Fereshteh Motamedi, Zehra Batool, Nima Naderi, Fatima Shaerzadeh, Anahita Zoghi, Omidvar Rezaei, Fariba Khodagholi, Hamid Gholami Pourbadie   +8 more
wiley   +1 more source

The Biological Activities of Polyether Ionophore Antibiotic Routiennocin is Independent of Absolute Stereochemistry

ChemBioChem, Volume 25, Issue 7, April 2, 2024.
A convergent synthesis was used to access both enantiomers of the polyether antibiotic routiennocin, and a diastereomeric variant, to probe the biological consequences of altering the naturally configured stereochemistry. Testing these compounds against a broad panel of bacteria and mammalian cells revealed independence of absolute stereochemistry in ...
Søren Lau Borcher Møller, Michelle H. Rasmussen, Jun Li, Esben B. Svenningsen, Gustav J. Wørmer, Thomas Tørring, Thomas B. Poulsen   +6 more
wiley   +1 more source

in bone marrow-derived mast cells [PDF]

, 2012
Cinnamomum cambodianum has been used as a traditional medicine in Cambodia. Its effect on the bone marrow-derived mast cells (BMMCs) mediated allergic response remains unknown. In this study, a chloroform-soluble extract of C.
Hyeong-Kyu Lee, P Khiev, Y W Chin, Sei-Ryang Oh, Hee Sung Chae, Piseth Khiev, Hee-Sung Chae, Sei Ryang Oh, Hyeong Kyu Lee, Young-Won Chin   +9 more
core   +1 more source

Diversity and Screening of Cellulolytic Microorganisms from Mangrove Forests, Natural Parks, Paddy Field, and Sugarcane Plantation in Panay Island, Philippines

International Journal of Microbiology, Volume 2024, Issue 1, 2024.
Cellulolytic microorganisms secrete cellulase, which plays a crucial role in the conversion of lignocellulosic biomass into value‐added products with diverse applications in industries, such as biofuel, healthcare, and agriculture. As the world transitions to a bioenergy future, cellulase demand is likely to expand.
Isabel Grace T. Gatpatan, Rhudith B. Cabulong, Resurreccion B. Sadaba, Diriba Muleta   +3 more
wiley   +1 more source

Selective Complexation and Transport of Calcium by Carboxylic Ionophores [PDF]

, 1989
International audienceIn the growing class of carboxylic polyether ionophores isolated from bacterial strains, calcimycin(A-23187) occupies an unusual place for divalent cation, especially calcium.
Jeminet, Georges, Albrecht-Gary, Anne-Marie, Blanc, Sylvie   +2 more
core   +2 more sources

A23187 (Calcimycin): Structure and Interaction in Relation to its Transmembrane Calcium-ion Transport [PDF]

, 1992
Studies using IR, UV, CD, fluorescence, and NMR techniques on the calcium ionophore A23187 (calcimycin) under various conditions clearly showed that the mol. exists as a stable dimer in nonpolar solvents and aggregates further into a stacked dimeric pore

core  

Alterations in voltage-sensing of the mitochondrial permeability transition pore in ANT1-deficient cells [PDF]

, 2017
The probability of mitochondrial permeability transition (mPT) pore opening is inversely related to the magnitude of the proton electrochemical gradient. The module conferring sensitivity of the pore to this gradient has not been identified.
Chinopoulos, Christos, Manfredi G, Starkov A, Törőcsik, Beáta, Dóczi, Judit, Ádám, Veronika, Molnár, Mária Judit, Gál, Anikó, Mousson de Camaret B, Starkova N, Echaniz-Laguna A, Kawamata H   +11 more
core   +1 more source

Anti-allergic effect of lambertianic acid fromThuja orientalisin mouse bone marrow-derived mast cells [PDF]

, 2011
Lambertianic acid is a bioactive diterpene found in the leaves of Thuja orientalis. Its effect on the bone marrow-derived mast cell (BMMC) mediated allergy and inflammation mechanism remains unknown. In this study, lambertianic acid was evaluated for its
Young Won Chin, Hee Sung Chae, Hee-Sung Chae, Young-Won Chin   +3 more
core   +1 more source