Results 41 to 50 of about 2,749 (172)

Role of Calcimycin in Regulation of Autophagy in THP-1 Cells [PDF]

, 2015
Mycobacterium tuberculosis (M. tb), is the known pathogen for causing tuberculosis. It infects approximately one­ third of the world’s population. According to the global tuberculosis report 2013 by WHO, Tuberculosis remains a major global health problem.
Muni, Uttam Chetan
core  

Effect of Calcimycin Regulated Autophagy on Nuclear Receptor HNF-4a Expression in THP-1 Cells [PDF]

, 2015
Nuclear receptors (NRs) include 49 members and belong to family that function as ligand-inducible transcription factors. The basic structure of nuclear receptors involves the n - terminal transactivation domain and c - terminal ligand binding domain ...
Kumari, Pratibha
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Discovery and In Vitro Reconstitution of Closoxazole Biosynthesis from Pyxidicoccus fallax

ChemBioChem, Volume 26, Issue 10, May 27, 2025.
The myxobacterium Pyxidicoccus fallax is found to be a producer of benzoxazole‐containing natural products named closoxazoles. In vitro studies with the biosynthetic enzymes reveal new insights into the reaction mechanism for closoxazole formation.
Lucia Lernoud, Rimonda Jakob, Lars Warnick, Marie Luisa Marx, Lea Winand   +4 more
wiley   +1 more source

Production, Fate and Pathogenicity of Plasma Microparticles in Murine Cerebral Malaria [PDF]

, 2014
In patients with cerebral malaria (CM), higher levels of cell-specific microparticles (MP) correlate with the presence of neurological symptoms.
Combes, V, El-Assaad, F, Grau, GER, Hunt, NH, Wheway, J   +4 more
core   +4 more sources

Photodynamic Inactivation of the Sarcoplasmic Reticulum Ca2+‐ATPase by a Ruthenium Polypyridyl Complex Featuring π‐Expansive Ligands

Bioinorganic Chemistry and Applications, Volume 2025, Issue 1, 2025.
Sarcoplasmic reticulum Ca2+‐ATPase (SERCA) is a key protein involved in calcium homeostasis and the pivotal role of Ca2+ in a plethora of biological activities makes SERCA a powerful biological target. The intertwining between Ca2+ signalling and reactive oxygen species (ROS) has drawn much attention to investigate the photodynamic effect that ...
Gina Elena Giacomazzo, Gloria Mulas, Ilaria Palchetti, Luca Conti, Francesco Tadini-Buoninsegni, Barbara Valtancoli, Francesca Cencetti, Claudia Giorgi, Demetrio Milea   +8 more
wiley   +1 more source

Nuclear patterns of human breast cancer cells during apoptosis: characterisation by fractal dimension and co-occurrence matrix statistics [PDF]

, 2018
An analytical strategy combining fractal geometry and grey-level co-occurrence matrix (GLCM) statistics was devised to investigate ultrastructural changes in oestrogen-insensitive SK-BR3 human breast cancer cells undergoing apoptosis in vitro.
Castelli, Christian, Losa, Gabriele
core  

Identification of Pharmacological Modulators of HMGB1-Induced Inflammatory Response by Cell-Based Screening [PDF]

, 2013
High mobility group box 1 (HMGB1), a highly conserved, ubiquitous protein, is released into the circulation during sterile inflammation (e.g. arthritis, trauma) and circulatory shock.
A Lahat, AJ Ghio, AM Colangelo, B Cai, B Lu, C Lagathu, C Szabo, Csaba Szabo, D Ditsworth, D Gero, D Gero, Domokos Gerö, E Venereau, EA Park, GY Chen, H Schierbeck, H Selye, H Wang, H Yang, H Yang, H Yang, HE Harris, Huan Yang, J Evankovich, J Szelenyi, John P. Pribis, JR Klune, Katalin Módis, Kevin J. Tracey, KJ Tracey, L Ulloa, ME Bianchi, O Hori, Petra Szoleczky, PJ Barnes, R Bertini, Robert W. Sobol, Sangeeta Chevan, Timothy R. Billiar, U Andersson, Yousef Al-Abed   +40 more
core   +4 more sources

Monocyte‐derived extracellular vesicles, stimulated by Trypanosoma cruzi, enhance cellular invasion in vitro via activated TGF‐β1

Journal of Extracellular Vesicles, Volume 13, Issue 11, November 2024.
Abstract During cell invasion, large Extracellular Vesicle (lEV) release from host cells was dose‐dependently triggered by Trypanosoma cruzi metacyclic trypomastigotes (Mtr). This lEV release was inhibited when IP3‐mediated Ca2+ exit from the ER and further Ca2+ entry from plasma membrane channels was blocked, but whilst any store‐independent Ca2 ...
Ephraim A. Ansa‐Addo, Paras Pathak, Maria V. McCrossan, Izadora Volpato Rossi, Mahamed Abdullahi, Dan Stratton, Sigrun Lange, Marcel I. Ramirez, Jameel M. Inal   +8 more
wiley   +1 more source

Regulation of patterned dynamics of local exocytosis in growth cones by netrin-1 [PDF]

, 2015
Axonal guidance and synaptic specification depends on specific signaling mechanisms that occur in growth cones. While several signaling pathways implicated in cone navigation have been identified, membrane dynamics in growth cones remains largely unknown.
Cotrufo, Tiziana, Martínez Mármol, Ramón, Ros i Torres, Oriol, Soriano García, Eduardo   +3 more
core   +2 more sources

Mitochondrial plasticity and synaptic plasticity crosstalk; in health and Alzheimer's disease

CNS Neuroscience &Therapeutics, Volume 30, Issue 8, August 2024.
The mechanism of mitochondrial transport within the neuron is mediated on the cytoskeleton. The retrograde (−) motion deployed the movement of mitochondria toward the cell body with the help of dynein, TRAK1/2, and Mrio1/2 protein. While anterograde (+) motion causes the movement toward the axon with the assistance of kinesin, TRAK1/2, and Miro1/2 ...
Fatemeh Sayehmiri, Fereshteh Motamedi, Zehra Batool, Nima Naderi, Fatima Shaerzadeh, Anahita Zoghi, Omidvar Rezaei, Fariba Khodagholi, Hamid Gholami Pourbadie   +8 more
wiley   +1 more source