Results 21 to 30 of about 2,749 (172)
Myosin light chain kinase is not a regulator of synaptic vesicle trafficking during repetitive exocytosis in cultured hippocampal neurons [PDF]
, 2006 The mechanism by which synaptic vesicles (SVs) are recruited to the release site is poorly understood. One candidate mechanism for trafficking of SVs is the myosin-actin motor system.
Goda, Y, Tokuoka, H
core +1 more source
Total Synthesis of Tetranormethyl-calcimycin
Agricultural and Biological Chemistry, 1987 The title compound 2 was synthesized. Asymmetric epoxidation of 9 followed by reductive cleavage of the epoxide 10 and acidification gave a symmetrical spiroketal (3), to which pyrrole and benzoxazole moieties were introduced in an efficient manner by the previously developed method.
Yoshiaki NAKAHARA +2 more
openaire +2 more sources
Identification of New Drug Candidates Against \u3cem\u3eBorrelia burgdorferi\u3c/em\u3e Using High-Throughput Screening [PDF]
, 2016 Lyme disease is the most common zoonotic bacterial disease in North America. It is estimated that .300,000 cases per annum are reported in USA alone. A total of 10%–20% of patients who have been treated with antibiotic therapy report the recrudescence of
Babar, Mustafeez Mujtaba +9 more
core +3 more sources
Stimulation of Ca2+‐ATPase Transport Activity by a Small‐Molecule Drug
ChemMedChem, Volume 16, Issue 21, Page 3293-3299, November 5, 2021., 2021 Electric insight: The interaction between the small‐molecule drug CDN1163 and sarcoplasmic reticulum Ca2+−ATPase was investigated by electrical current measurements. It was shown that CDN1163 reversibly binds to the ATPase protein and significantly enhances ATP‐dependent calcium translocation.
Giacomo Sordi +4 more
wiley +1 more source
The FASEB Journal, Volume 35, Issue 2, February 2021., 2021 Abstract Panton‐Valentine Leukocidin (PVL) is a bicomponent leukotoxin produced by 3%‐10% of clinical Staphylococcus aureus (SA) strains involved in the severity of hospital and community‐acquired infections. Although PVL was long known as a pore‐forming toxin, recent studies have challenged the formation of a pore at the plasma membrane, while its ...
Viola Mazzoleni +4 more
wiley +1 more source
International Journal of Electrochemical Science, 2013 The transport of cadmium and of copper ions across the artificially prepared model phospholipid (PL) membranes on the polycarbonate supports was studied in the present manuscript.
Martina Parisová +4 more
doaj +1 more source
The effects of immune challenge on phenoloxidase activity in locust salivary glands in vitro [PDF]
, 2008 Homogenates of salivary glands from Locusta migratoria possess phenoloxidase (PO) activity. This study investigates the activation of prophenoloxidase (PPO) in these glands in vitro. When freshly dissected salivary glands from L. migratoria are incubated
Ashida +14 more
core +1 more source
Synthesis and antimicrobial evaluation of some novel sulfonylamido-benzoxazoles [PDF]
, 2016 A series of 2-(p-substituted phenyl)-5-[(4-substituted phenyl) sulfonylamido]-benzoxazoles were synthesized and tested for their antimicrobial activities. The structures of the new derivatives were elucidated by spectral techniques.
Doğanc, Fatma +5 more
core +1 more source
Calcimycin-induced lens epithelial cell apoptosis contributes to cataract formation
Experimental Eye Research, 1995 Previous studies have shown that calcimycin induces cataract in organ culture. To investigate the mechanism of this induction, the viability of lens epithelial cells in calcimycin (calcium ionophore, A23187)-treated rat lenses were examined. During incubation of lenses with 5 microM calcimycin, apoptotic epithelial cells were found after a 2-hr ...
W C, Li +4 more
openaire +2 more sources
Calcium Ionophore, Calcimycin, KillsLeishmaniaPromastigotes by Activating Parasite Nitric Oxide Synthase [PDF]
BioMed Research International, 2017 Leishmaniasis is an infectious disease caused by protozoan parasites of the genusLeishmania. There is no vaccine against human leishmaniasis and the treatment of the disease would benefit from a broader spectrum and a higher efficacy of leishmanicidal compounds.
Igor Grekov +4 more
openaire +3 more sources