Results 1 to 10 of about 2,064 (114)
Polyether Ionophore Antibiotics Target Drug-Resistant Clinical Isolates, Persister Cells, and Biofilms [PDF]
Microbiology Spectrum, 2023 Polyether ionophores are complex natural products known to transport various cations across biological membranes. While several members of this family are used in agriculture (e.g., as anti-coccidiostats) and have potent antibacterial activity, they are ...
Malene Wollesen +8 more
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Synthesis and crystal structure of the bis-calcimycin anion–Ni2+ complex [PDF]
ARKIVOC, 2008 La structure aux rayons X du complexe [Ni(calcimycine) 2 ] montre deux conformations essentiellement identiques des deux ligands de la calcimycine dans l'association dimérique, dans cette famille d'ionophores. Dans le complexe du titre, le cation nickel (II) a un environnement de coordination octaédrique O 4 N 2 déformé.
M. Akkurt +5 more
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Calcium ionophore improves embryonic development and pregnancy outcomes in patients with previous developmental problems in ICSI cycles [PDF]
BMC Pregnancy and Childbirth, 2022 Background Calcium (Ca2+) ionophores are now mainly considered as efficient treatments for fertilization failure. Recently, its application for rescuing poor embryo development was proposed but still non-routine.
Xiaolei Chen +8 more
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Frontiers in Microbiology, 2017 Calcimycin is a unique ionophoric antibiotic that is widely used in biochemical and pharmaceutical applications, but the genetic basis underlying the regulatory mechanisms of calcimycin biosynthesis are unclear.
Tiesheng Han, Xiaoxia Wang, Fen Hu
exaly +3 more sources
Influence of Amino Acid Feeding on Production of Calcimycin and Analogs in Streptomyces chartreusis. [PDF]
Int J Environ Res Public Health, 2021 Streptomyces chartreusis NRRL 3882 produces the polyether ionophore calcimycin and a variety of analogs, which originate from the same biosynthetic gene cluster. The role of calcimycin and its analogs for the producer is unknown, but calcimycin has strong antibacterial activity.
Arend KI, Bandow JE.
europepmc +4 more sources
Jurnal Veteriner, 2016 The aim of study was to find out the best concentration and exposure time of calcimycin andionomycin in order to produce parthenogenetic embryos. Female Swiss Webster mice were fisrtlyprimed with Pregnant Mare’s Serum Gonadotropin (PMSG) and Human ...
Wilmientje Marlene Nalley +1 more
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Frontiers in Plant Science, 2021 MicroRNAs (miRNAs) are critical components of the multidimensional regulatory networks in eukaryotic systems. Given their diverse spectrum of function, it is apparent that the transcription, processing, and activity of the miRNAs themselves, is very ...
Shivani Kansal +3 more
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In vitro Activation of mouse oocytes through intracellular Ca2+ regulation
Journal of Human Reproductive Sciences, 2020 Background: Ca2+ signaling pathway is suggested to play an essential role in mediating oocyte maturation. Aims: The aim of this study was to evaluate intracellular Ca2+ of resistant immature oocytes that failed to resume meiosis following subsequent in ...
Nining Handayani +3 more
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Journal of Pharmaceutical Analysis, 2020 Nitric oxide (NO) is a second messenger playing crucial roles in the signaling of a variety of cellular functions. Due to its pathophysiological significance, various NO modulators have been developed to explore NO pathways and some have been used as ...
Ying Dong +4 more
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Total Synthesis of Tetranormethyl-calcimycin
Agricultural and Biological Chemistry, 1987 The title compound 2 was synthesized. Asymmetric epoxidation of 9 followed by reductive cleavage of the epoxide 10 and acidification gave a symmetrical spiroketal (3), to which pyrrole and benzoxazole moieties were introduced in an efficient manner by the previously developed method.
NAKAHARA, Yoshiaki +2 more
openaire +2 more sources