Results 1 to 10 of about 155,757 (387)
Amylin and Calcitonin: Potential Therapeutic Strategies to Reduce Body Weight and Liver Fat
Frontiers in Endocrinology, 2021 The hormones amylin and calcitonin interact with receptors within the same family to exert their effects on the human organism. Calcitonin, derived from thyroid C cells, is known for its inhibitory effect on osteoclasts.
David S. Mathiesen +10 more
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Pain, 2017 Calcitonin gene–related peptide (CGRP) is a 37-amino acid peptide found primarily in the C and Aδ sensory fibers arising from the dorsal root and trigeminal ganglia, as well as the central nervous system. Calcitonin gene–related peptide was found to play
S. Iyengar, M. Ossipov, Kirk W. Johnson
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Annals of Neurology, 2020 Calcitonin gene–related peptide (CGRP) pathway inhibitors are emerging treatments for migraine. CGRP‐mediated vasodilation is, however, a critical rescue mechanism in ischemia.
Inge A Mulder +2 more
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The Journal of Poultry Science, 2010 The present study was performed to demonstrate the presence of receptors for avian calcitonin (cCT) in ovarian granulosa cells of the largest follicle of laying hens and to determine the effect of cCT on LH-stimulated P4 production.
Kaori Nakagawa-Mizuyachi +4 more
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Calcitonin and Bone Physiology: In Vitro, In Vivo, and Clinical Investigations
International Journal of Endocrinology, 2020 Calcitonin was discovered as a peptide hormone that was known to reduce the calcium levels in the systemic circulation. This hypocalcemic effect is produced due to multiple reasons such as inhibition of bone resorption or suppression of calcium release ...
Jingbo Xie +9 more
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Rimegepant, an Oral Calcitonin Gene–Related Peptide Receptor Antagonist, for Migraine
New England Journal of Medicine, 2019 BACKGROUND Calcitonin gene-related peptide receptor has been implicated in the pathogenesis of migraine. Rimegepant is an orally administered, small-molecule, calcitonin gene-related peptide receptor antagonist that may be effective in acute migraine ...
Richard B Lipton +2 more
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Frontiers in Endocrinology, 2020 Calcitonin is a small peptide hormone secreted from the parafollicular cells of the thyroid gland in response to an increase in serum calcium. The inhibition of osteoclastic resorption is the main mechanism by which calcitonin quickly decreases ...
Chen-Yuan Hsiao +11 more
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Frontiers in Physiology, 2018 Calcitonin gene-related peptide (CGRP) is a highly potent vasoactive peptide released from sensory nerves, which is now proposed to have protective effects in several cardiovascular diseases.
Zizheng Kee, Susan D Brain
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The safety and efficacy of long-term use of calcitonin analogs in the treatment of osteoporosis in the elderly: a pharmacovigilance and RCT meta-analysis [PDF]
Frontiers in PharmacologyBackgroundOsteoporosis is a common metabolic bone disease in the elderly, and its incidence continues to rise with the global aging population. Calcitonin analogs (including synthetic salmon, human, and porcine calcitonin preparations) are a classic ...
Lingjie Tan, Bin Sheng, Sui Deng
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Amylin Receptor 1 Mutagenesis Revealed a Potential Role of Calcitonin Serine 29 in Receptor Interaction [PDF]
BiomedicinesBackground: The amylin receptor is a receptor for the peptide hormone amylin, and its activation is known to reduce body weight. The amylin receptor functions as a heterodimer complex that consists of the calcitonin receptor for peptide hormone ...
Hyeseon Song +5 more
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