Results 41 to 50 of about 101,964 (348)
The inhibitory effect of salmon calcitonin on tri-iodothyronine induction of early hypertrophy in articular cartilage. [PDF]
PLoS ONE, 2012 Salmon calcitonin has chondroprotective effect both in vitro and in vivo, and is therefore being tested as a candidate drug for cartilage degenerative diseases.
Pingping Chen-An +5 more
doaj +1 more source
Thermo-Sensitive mPEG-PA-PLL Hydrogel for Drug Release of Calcitonin
Gels, 2022 The oral route is the most popular way of drug administration because of good patient compliance and ease of use. However, the oral delivery of peptides and proteins is difficult, mainly due to poor oral bioavailability. In past decades, researchers have
Yu-En Cheng +3 more
doaj +1 more source
Radioimmunoassay for calcitonin.
Clinical Chemistry, 1982 Calcitonin (CT) is one of the most recently discovered calcium-regulating hormones; the first brief allusion to its existence appeared in 1961.1 The first assays for CT were based on its hypocalcemic property upon injection into rats.2,3 Radioimmunoassays for animal calcitonins soon followed, but the availability of sensitive radioimmunoassays for ...
Hunter Heath, Glen W. Sizemore
openaire +3 more sources
Surgical Case Reports, 2022 Background Calcitonin-producing pancreatic neuroendocrine neoplasms (PanNENs) are extremely rare. There have been no reports of a patient in whom liver metastases were the presenting finding, and a calcitonin-producing PanNEN was subsequently detected ...
Ryusei Yamamoto +6 more
doaj +1 more source
Mesoporous Bioactive Glasses: A Powerful Tool in Tissue Engineering and Drug Delivery
Advanced Healthcare Materials, EarlyView.This work is a comprehensive revision of bioactive glasses (BGs), pioneered by Prof. L.L. Hench, which are key in bone repair and regenerative medicine. Sol–gel methods and mesoporous designs enhanced their bioactivity, ions, and drug delivery. BGs now support gene therapy and 3D‐printed scaffolds, enabling personalized, multifunctional treatments in ...
Natividad Gómez‐Cerezo +3 more
wiley +1 more source
Strategies to Improve the Lipophilicity of Hydrophilic Macromolecular Drugs
Advanced Healthcare Materials, EarlyView.Hydrophilic macromolecular drugs can be successfully lipidized by covalent attachment of lipids, by hydrophobic ion pairing with negatively or positively charged surfactants, and by dry or wet reverse micelle formation. Lipophilicity enhancement of hydrophilic macromolecules has several benefits including stability and bioavailability improvement ...
Sera Lindner +8 more
wiley +1 more source
Calcitonin-gene related peptide and disease activity in cluster headache
Cephalalgia, 2019 Objective To investigate the role of calcitonin gene-related peptide, pituitary adenylate cyclase-activating polypeptide-38 (PACAP38) and vasoactive intestinal polypeptide in cluster headache, we measured these vasoactive peptides interictally and during
A. Snoer +9 more
semanticscholar +1 more source
Advanced Science, EarlyView.This study shows that diabetes damages sensory nerve fibers, especially CGRP‐positive ones, in the periodontium and disrupts autophagy in trigeminal ganglion neurons, affecting bone homeostasis by inhibiting type H vessel formation. To address this, CGRP@PVA/tsPBA hydrogels are developed to release CGRP in response to ROS, which binds to endothelial ...
Chaoning Zhan +7 more
wiley +1 more source
Advanced Science, EarlyView.Recent research has shown that biodegradable metals based on zinc (Zn) may be used as guided bone regeneration (GBR) membrane materials. This study examines their viability from the standpoints of material science and biology, reports on the state of research on Zn‐based GBR membranes, and suggests specific development plans based on the potential and ...
Kai Chen +12 more
wiley +1 more source
ERBB1- and ERBB2-Positive Medullary Thyroid Carcinoma: A Case Report
Diseases, 2018 Medullary thyroid carcinomas (MTCs) are rare thyroid tumors occurring in both sporadic and hereditary forms, whose pathogenesis is related to RET proto-oncogene alterations.
Michele Minuto +5 more
doaj +1 more source